Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher Guerin"'
Autor:
Frédéric Vendeuvre, Christopher Guerin
Les entreprises vivent aujourd'hui dans une atmosphère volatile, incertaine et complexe. Pour les forces commerciales, cela se traduit par de grandes difficultés. Ainsi, beaucoup d'entreprises doivent opérer une transformation commerciale pour se
Publikováno v:
Biochemical and Biophysical Research Communications. 273:287-293
Strategies that antagonize growth factor signaling are attractive candidates for the biological therapy of brain tumors. HGF/NK2 is a secreted truncated splicing variant and potential antagonist of scatter factor/hepatocyte growth factor (SF/HGF), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b9f9885f04cc0b6847e9ba3f2730ac
https://doi.org/10.1006/bbrc.2000.2935
https://doi.org/10.1006/bbrc.2000.2935
Publikováno v:
Brain Research. 640:98-104
Blood-brain barrier (BBB) properties of endothelial cells have on impact on brain tumor behavior, diagnosis, and response to therapy. Biochemical BBB properties are expressed by endothelial cells within intracerebral (IC) gliomas but little is known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dcfc9cc8338ea1da330d259ead3526
https://doi.org/10.1016/0006-8993(94)91861-9
https://doi.org/10.1016/0006-8993(94)91861-9
Autor:
Henry Brem, Lester R. Drewes, Christopher Guerin, Johannes E. A. Wolff, John Laterra, Gary W. Goldstein
Publikováno v:
Annals of Neurology. 31:481-487
The GLUT1 isoform of the glucose transporter is normally expressed at high levels in differentiated brain vessels that also express a permeability barrier. In contrast, malignant brain neoplasms have relatively undifferentiated vessels that are highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82dc08804a4b26ee24e48c5ce6fd995
https://doi.org/10.1002/ana.410310504
https://doi.org/10.1002/ana.410310504
Autor:
Christopher Guerin, Lester R. Drewes, Henry Brem, Ralph H. Hruban, John Laterra, Gary W. Goldstein
Publikováno v:
Annals of Neurology. 28:758-765
The glucose transporter of the human brain has been localized to endothelial cells expressing the blood-brain barrier, but little is known regarding its mechanism of induction or whether its expression is exclusively linked with restricted vascular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5504251f3c68acbaa6598b04a01cbc3e
https://doi.org/10.1002/ana.410280606
https://doi.org/10.1002/ana.410280606
Publikováno v:
Investigational new drugs. 22(1)
New approaches to malignant glioma are being actively investigated. Local drug delivery directly to the site of the tumor is one novel approach that has been approved by the US FDA and other regulatory agencies worldwide. This agent, Gliadel®, deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ef9bf48fcf0cb39060618b867f722f
https://pubmed.ncbi.nlm.nih.gov/14707492
https://pubmed.ncbi.nlm.nih.gov/14707492
Autor:
Christopher Guerin, Ravi R. Indurti, John Laterra, Henry Brem, Gary W. Goldstein, Joseph Bressler, Johannes E.A. Wolff
Publikováno v:
Brain research. 604(1-2)
Angiogenesis, a process dependent upon perivascular proteolysis, is required for solid tumor growth and is inhibited by certain steroids including glucocorticoids. We examined the relationship between tumor growth and vessel density in experimental r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd75a0181e6ed2747b9f9806b10d956d
https://pubmed.ncbi.nlm.nih.gov/7681348
https://pubmed.ncbi.nlm.nih.gov/7681348
Publikováno v:
Biochemical and biophysical research communications. 188(2)
The potential of angiogenesis inhibitors as therapy for human diseases is limited by a lack of clinically available agents. We investigated the mechanism of the anti-angiogenesis effects of minocycline, a commonly used drug, and several derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c35e36d450fc9e7a9c8281141ed162
https://pubmed.ncbi.nlm.nih.gov/1445318
https://pubmed.ncbi.nlm.nih.gov/1445318
Publikováno v:
Angiogenesis in Health and Disease ISBN: 9781461364818
Despite enormous advances in clinical medicine, the prognosis of primary malignant brain neoplasms remains dismal. Currently, the most effective therapies result in a median survival of less than one year, with the majority of patients dying within t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c02160e4748278f00cf5b44122a2d2e0
https://doi.org/10.1007/978-1-4615-3358-0_24
https://doi.org/10.1007/978-1-4615-3358-0_24