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pro vyhledávání: '"Christopher Grimaldi"'
Autor:
Christopher C. Goodnow, J. Christopher Grimaldi, Frances E. Lund, Andrew W. Heath, R. M. E. Parkhouse, Nanette Solvason, Michael P. Cooke, Maureen Howard
Publikováno v:
European Journal of Immunology. 25:1338-1345
CD38 is a 42-kDa membrane associated enzyme which converts NAD into cyclic ADP-ribose (cADPR), a Ca(2+)-mobilizing second messenger, and ADP-ribose (ADPR). Agonistic antibodies to murine CD38 deliver a potent growth co-stimulus to mature splenic B ly
Autor:
Timothy C. Meeker, Bruce Shiramizu, Lawrence Kaplan, Brian Herndier, Henry Sanchez, J. Christopher Grimaldi, James Baumgartner, Jacob Rachlin, Ellen Feigal, Mark Rosenblum, Michael S. McGrath
Publikováno v:
AIDS. 5:669-674
The pathogenesis of the HIV-associated lymphomas is not well understood. In order to begin characterizing this class of lymphoma, we initiated a molecular genetic study of DNA extracted from 31 diagnostic biopsy specimens from patients diagnosed with
Autor:
Ming-Hong Xie, Bernard Chow, James Lee, Audrey Goddard, Daryl T. Baldwin, Yisheng Jin, Kevin P. Baker, Sherry Heldens, Guoying Yu, Paul J. Godowski, Jean Yuan, Christopher Grimaldi, Jennifer Singh, Alicia Vagts, Clarissa Chui, Dongzhou Liao, Bethanne Deuel, Austin L. Gurney, Min Zhang, Daniel G. Yansura, David Wieand, Patrick Dowd, William I. Wood, Qimin Gu, Lhney Lewis, Somasekar Seshagiri, Jill Schoenfeld, Kathryn Woods, Richard Vandlen, Laura Klimowski, Evangeline Abaya, Zemin Zhang, Melanie R. Mark, Jeremy Stinson, Edward P. Robbie, Hok Seon Kim, Victoria Smith, Craig Crowley, Jessica Foster, Laura Simmons, Bridget Currell, Stephanie Johnson, Colin K. Watanabe, Dan L. Eaton, Jennifer Brush, Jian Chen, Hilary Clark, Sothy Yi, Philip E. Hass, Celina Sanchez, Arthur J Huang
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bfd6259edc7f041ff31d6f8b811d17
https://europepmc.org/articles/PMC403697/
https://europepmc.org/articles/PMC403697/
Publikováno v:
Hybridoma. 18(2)
CD38 is expressed on a variety of hematopoietic cells and has a unique enzymatic activity that converts nicotinamide adenine dinucleotide (NAD) into cyclic ADP-ribose (cADPR) and then into ADPR. CD38 is expressed at increasingly higher levels on B ce
Autor:
R. Michael, Frances E. Lund, Maureen Howard, Nanette Solvason, J. Christopher Grimaldi, E. Parkhouse
Publikováno v:
Immunology today. 16(10)
CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lun
Autor:
Randolph N. Mohr, David A. Largaespada, Satoshi Tsukada, Lucie Cohen, Douglas C. Saffran, Maureen C. Howard, J. Fernando Bazan, Owen N. Witte, Nancy A. Jenkins, David J. Rawlings, J. Christopher Grimaldi, Neal G. Copeland
Publikováno v:
Science (New York, N.Y.). 261(5119)
The cytoplasmic tyrosine kinase, Bruton's tyrosine kinase (Btk, formerly bpk or atk), is crucial for B cell development. Loss of kinase activity results in the human immunodeficiency, X-linked agammaglobulinemia, characterized by a failure to produce
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