Proverbios y desarrollo humano

Autor: Christopher Gallardo-Cerón, Sandro Rodríguez-Suárez

Publikováno v: Ciencia y Deporte, Vol 6, Iss 1, Pp 110-115 (2021)

Aunque hay muchos jugadores, pocos conocen la mayoría de los proverbios, los cuales son cruciales para avanzar de nivel, esto es igual de importante que comprender que el shogi va más allá de ser solo el juego, la filosofía que lo envuelve, sus e

Externí odkaz: https://doaj.org/article/e9c378291d8648ca995754efe878c0c0

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

Autor: Peter J. Teravskis, Michael K. Lee, Carmen Nanclares, Balvindar Singh, Alfonso Araque, Emmanuel Okematti, Héctor A. Martell-Martínez, Joyce Meints, Mathew A. Sherman, Sylvain Lesné, Michael A. Benneyworth, Alena Savonenko, Christopher Gallardo, Dezhi Liao, Ana Covelo

Publikováno v: Acta Neuropathologica

Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are clinically and neuropathologically highly related α-synucleinopathies that collectively constitute the second leading cause of neurodegenerative dementias. Genetic and neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7782aededc54d3caa9d04e48ca50e0a
http://europepmc.org/articles/PMC6778173

Conditional Deletion ofPrnpRescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease

Autor: Sophie A. Robinson, Christopher Gallardo, Charlotte Herber, Jean Manson, Laura T. Haas, Stephen M. Strittmatter, Santiago V. Salazar, Adam C. Kaufman, Michael K. Lee

Publikováno v: Salazar, S, Gallardo, C, Kaufman, A, Herber, C, Haas, L, Robinson, S, Manson, J, Lee, M & Strittmatter, S 2017, ' Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease ', Journal of Neuroscience, vol. 37, no. 38, pp. 9207-9221 . https://doi.org/10.1523/JNEUROSCI.0722-17.2017

Biochemical and genetic evidence implicate soluble oligomeric amyloid-β (Aβo) in triggering Alzheimer's disease (AD) pathophysiology. Moreover, constitutive deletion of the Aβo-binding cellular prion protein (PrPC) prevents development of memory d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ddfaaa0f18a72be240ae244611a4ca
https://doi.org/10.1523/jneurosci.0722-17.2017

Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration

Autor: Christopher Gallardo, Rebecca J. Kapphahn, Deborah A. Ferrington, Marcia R. Terluk, Hwee Gong, Sandra R. Montezuma, Lauren M. Soukup

Publikováno v: The Journal of Neuroscience. 35:7304-7311

Age-related macular degeneration (AMD) is the leading cause of blindness among older adults in the developed world. Although the pathological mechanisms have not been definitively elucidated, evidence suggests a key role for mitochondrial (mt) dysfun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ba6063d5e1a1db22ad0196445b653c
https://doi.org/10.1523/jneurosci.0190-15.2015

HDAC Inhibitors Restore the Capacity of Aged Mice to Respond to Haloperidol through Modulation of Histone Acetylation

Autor: Nicolas Gerst, Mitsuyuki Matsumoto, Jack Keegan, Deyu Fang, Chris Tucker, Christopher Gallardo, Kazuhiro Tetsuka, John G. Csernansky, Janitza L. Montalvo-Ortiz, Hongxin Dong

Publikováno v: Neuropsychopharmacology. 39:1469-1478

Antipsychotic drugs are widely prescribed to elderly patients for the treatment of a variety of psychopathological conditions, including psychosis and the behavioral disturbances associated with dementia. However, clinical experience suggests that th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401ebc74c81e2e0b14ba53776e069fda
https://doi.org/10.1038/npp.2013.346