Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christopher G. Knight"'
Autor:
Paul M. Campbell, Thomas Willmott, Angela Summers, Christopher G. Knight, Gavin J. Humphreys, Joanne E. Konkel, Titus Augustine, Andrew J. McBain
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT The oral microbiome is influenced by environmental factors in chronic kidney disease and following kidney transplantation affecting microbial composition, which may have implications for health and recovery. A major driver of oral microbiome
Externí odkaz:
https://doaj.org/article/5db8c0a01af04d1cb91a74a5e187a12d
Autor:
Paul M. Campbell, Thomas Willmott, Gavin J. Humphreys, Oana Piscoran, Houda Chea, Angela M. Summers, Joanne E. Konkel, Christopher G. Knight, Titus Augustine, Andrew J. McBain
Publikováno v:
Frontiers in Microbiomes, Vol 2 (2023)
IntroductionChronic kidney disease (CKD) may affect the human microbiome via increased concentrations of uremic toxins such as urea and creatinine. MethodsWe have profiled the oral microbiota in patients with CKD before and one week after kidney tran
Externí odkaz:
https://doaj.org/article/8b7c3b3f41fa4d68a2c8bd18d4ea69bb
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Clark et al. comprehensively explore the primary structural features underlying the activity of a complete set of antimicrobial peptides (AMPs). They find that the shortest active peptides were 4 or 5 residues in length, with activity being associate
Externí odkaz:
https://doaj.org/article/07077bdf64fe48439afbfe1eab85d91f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Findings from gut microbiome studies are strongly influenced by both experimental and analytical factors that can unintentionally bias their interpretation. Environment is also critical. Both co-housing and maternal effects are expected to a
Externí odkaz:
https://doaj.org/article/dd2e2f3314e44cd681b20f0ea2334bf2
Autor:
Paul M. Campbell, Gavin J. Humphreys, Angela M. Summers, Joanne E. Konkel, Christopher G. Knight, Titus Augustine, Andrew J. McBain
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The role of the human microbiome in health and disease is becoming increasingly apparent. Emerging evidence suggests that the microbiome is affected by solid organ transplantation. Kidney transplantation is the gold standard treatment for End-Stage R
Externí odkaz:
https://doaj.org/article/fbb3ff3012514e5fb840bf55568f26b3
Autor:
Rok Krašovec, Roman V. Belavkin, John A.D. Aston, Alastair Channon, Elizabeth Aston, Bharat M. Rash, Manikandan Kadirvel, Sarah Forbes, Christopher G. Knight
Publikováno v:
Microbial Cell, Vol 1, Iss 7, Pp 250-252 (2014)
We do not need to rehearse the grim story of the global rise of antibiotic resistant microbes. But what if it were possible to control the rate with which antibiotic resistance evolves by de novo mutation? It seems that some bacteria may already do e
Externí odkaz:
https://doaj.org/article/a2914fa396a4493e8794be5d25869947
Environmental and genetic influence on rate and spectrum of spontaneous mutations inEscherichia coli
Autor:
Danna R. Gifford, Anish Bhattacharyya, Alexandra Geim, Eleanor Marshall, Rok Krašovec, Christopher G. Knight
Spontaneous mutations are the ultimate source of novel genetic variation on which evolution operates. While mutation rate is commonly described as a single parameter in evolutionary models, it is increasingly evident that mutation rates vary due to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fe934b24a1dc7fcf0a767552924791
https://doi.org/10.1101/2023.04.06.535897
https://doi.org/10.1101/2023.04.06.535897
Autor:
Paul M Campbell, Verena Toedtling, Gavin J Humphreys, Christopher G Knight, Hugh Devlin, Andrew J McBain
Publikováno v:
Journal of Applied Microbiology. 134
AimsLong-term retention of impacted third molars (wisdom teeth) is associated with plaque stagnation and the development of caries on the adjacent surface of the neighboring second molar. While caries and tooth loss are common outcomes of impaction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688435845ac654c224b6aceaec7d4c70
https://doi.org/10.1093/jambio/lxac054
https://doi.org/10.1093/jambio/lxac054
Autor:
Katharine Z. Coyte, Cagla Stevenson, Christopher G. Knight, Ellie Harrison, James P. J. Hall, Michael A. Brockhurst
Publikováno v:
Coyte, K Z, Stevenson, C, Knight, C G, Harrison, E, Hall, J P J & Brockhurst, M A 2022, ' Horizontal gene transfer and ecological interactions jointly control microbiome stability ', PLoS Biology, vol. 20, no. 11, e3001847 . https://doi.org/10.1371/journal.pbio.3001847
Genes encoding resistance to stressors, such as antibiotics or environmental pollutants, are widespread across microbiomes, often encoded on mobile genetic elements. Yet, despite their prevalence, the impact of resistance genes and their mobility upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216aadad7adc4917934aaab02ae0af17
https://doi.org/10.1371/journal.pbio.3001847
https://doi.org/10.1371/journal.pbio.3001847
Autor:
Danna R. Gifford, Ernesto Berríos-Caro, Christine Joerres, Marc Suñé, Jessica H. Forsyth, Anish Bhattacharyya, Tobias Galla, Christopher G. Knight
Antibiotic combination therapies are an approach used to counter the evolution of resistance; their purported benefit is they can stop the successive emergence of independent resistance mutations in the same genome. Here, we show that bacterial popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f3c4184912a9b6231226c0f6368fe0
https://doi.org/10.1101/643585
https://doi.org/10.1101/643585