Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christopher G. Horton"'
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Toll-like receptors (TLRs) are important innate immune receptors for the identification and clearance of invading pathogens. Twelve TLRs that recognize various conserved components of microorganisms are currently known. Among these, the endosomal TLR
Externí odkaz:
https://doaj.org/article/88dfa4310ff3477689bc83b4a15738d6
Autor:
Jacen S. Maier-Moore, A. Darise Farris, Zijian Pan, Christopher G. Horton, Christina Lawrence, Anthony W. Confer, K. Mark Coggeshall, Shirley A. Mathews
Publikováno v:
Arthritis & Rheumatology. 66:2521-2531
Objective To assess disease features in Sle1.Yaa mice with genetic interleukin-6 (IL-6) deficiency. Methods Sera and tissues were collected from C57BL/6 (B6), Sle1.Yaa, and Sle1.Yaa.IL-6−/− mice and analyzed for various features of disease. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb75f7ca93a2bc4657db24f768ae86f
https://doi.org/10.1002/art.38716
https://doi.org/10.1002/art.38716
Publikováno v:
The Journal of Immunology. 198:150.15-150.15
CD4+ T helper cells are a diverse group of cells promoting target cell death and production of antibodies. These cells acquire one of several fates following signals through the T cell receptor, co-receptors, and cytokines. The cytokine requirements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e5a53bd0b213d6cd599c4efc12b4779
https://doi.org/10.4049/jimmunol.198.supp.150.15
https://doi.org/10.4049/jimmunol.198.supp.150.15
Autor:
Ashna Dhoonmoon, Christopher G Horton
Publikováno v:
The Journal of Immunology. 198:152.18-152.18
T lymphocytes require two signals for appropriate activation – signal one is obtained via antigen presentation to the T cell receptor and signal two is provided by a co-receptor. In the absence of signal two, T cells remain unresponsive, thus these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc6a04a4b7ff0d7b99a5b669d9e78c73
https://doi.org/10.4049/jimmunol.198.supp.152.18
https://doi.org/10.4049/jimmunol.198.supp.152.18
Publikováno v:
Current allergy and asthma reports. 12(1)
Toll-like receptors have attracted increased attention in recent years, not only for their role in sensing conserved microbial components, but also in the realm of autoimmunity. Though TLRs are most widely known for their capacity to detect conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9aad783d66cb021c4d1e6971c85ce48
https://pubmed.ncbi.nlm.nih.gov/22086298
https://pubmed.ncbi.nlm.nih.gov/22086298
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2010 (2010)
Mediators of Inflammation, Vol 2010 (2010)
Toll-like receptors (TLRs) are important innate immune receptors for the identification and clearance of invading pathogens. Twelve TLRs that recognize various conserved components of microorganisms are currently known. Among these, the endosomal TLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe09646f4e103d511204412295a3985
https://pubmed.ncbi.nlm.nih.gov/20886024
https://pubmed.ncbi.nlm.nih.gov/20886024