Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christopher G Rowe"'
Autor:
Puthupparampil V Scaria, Beth Chen, Christopher G Rowe, David S Jones, Emma Barnafo, Elizabeth R Fischer, Charles Anderson, Nicholas J MacDonald, Lynn Lambert, Kelly M Rausch, David L Narum, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in
Externí odkaz:
https://doaj.org/article/2a694a1e2ca147cf9e3a3357db15e749
Autor:
David S Jones, Christopher G Rowe, Beth Chen, Karine Reiter, Kelly M Rausch, David L Narum, Yimin Wu, Patrick E Duffy
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0138761 (2016)
A practical method is described for synthesizing conjugated protein nanoparticles using thioether (thiol-maleimide) cross-linking chemistry. This method fills the need for a reliable and reproducible synthesis of protein conjugate vaccines for precli
Externí odkaz:
https://doaj.org/article/7ae623226dd943ff8db6cde05f050114
Autor:
Puthupparampil V. Scaria, Nicole Roth, Kim Schwendt, Olga V. Muratova, Nada Alani, Lynn E. Lambert, Emma K. Barnafo, Christopher G. Rowe, Irfan U. Zaidi, Kelly M. Rausch, David L. Narum, Benjamin Petsch, Patrick E. Duffy
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Malaria transmission-blocking vaccines (TBV) are designed to inhibit the sexual stage development of the parasite in the mosquito host and can play a significant role in achieving the goal of malaria elimination. Preclinical and clinical stu
Externí odkaz:
https://doaj.org/article/c1b01465fd85446dbc27c45b0c566753
Autor:
Puthupparampil V. Scaria, Olga Muratova, Emma Barnafo, Elizabeth R. Fischer, Debbie D. Nahas, Lynn Lambert, Bob J. Lucas, Beth Chen, Christopher G. Rowe, David L. Narum, Patrick E. Duffy, Irfan Zaidi, Charles Anderson
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 4, Iss 1, Pp 1-10 (2019)
npj Vaccines, Vol 4, Iss 1, Pp 1-10 (2019)
Malaria transmission blocking vaccines (TBV) target the mosquito stage of parasite development by passive immunization of mosquitoes feeding on a vaccinated human. Through uptake of vaccine-induced antibodies in a blood meal, mosquito infection is ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1725b9fe0fa48b334da50bd7441443f9
https://doi.org/10.1038/s41541-019-0121-9
https://doi.org/10.1038/s41541-019-0121-9
Autor:
David L. Narum, Elizabeth R. Fischer, Emma Barnafo, Kelly M. Rausch, David S. Jones, Lynn Lambert, Christopher G. Rowe, Beth Chen, Charles Anderson, Patrick E. Duffy, Nicholas J. MacDonald, Puthupparampil V. Scaria
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
PLoS ONE, Vol 12, Iss 12, p e0190312 (2017)
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc09cb29f7789f2d457e48425e037a3c
http://europepmc.org/articles/PMC5744994
http://europepmc.org/articles/PMC5744994
Publikováno v:
Antiviral Research. 85:525-531
Infectious pancreatic necrosis virus (IPNV) is a major viral pathogen of salmonid fish and causes serious economic losses to salmonid aquaculture. Previously, we demonstrated that the IPNV capsid protein, VP2, expressed in yeast self-assembles into s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd23e7f9672cdd3cc74b116212088e6
https://doi.org/10.1016/j.antiviral.2009.12.009
https://doi.org/10.1016/j.antiviral.2009.12.009
Autor:
Michal Fried, Christopher G. Rowe, Marion Avril, Severin Gose, David L. Narum, Bridget R. Kulasekara, Madeleine Dahlbäck, Patrick E. Duffy, Ali Salanti, Lynda Misher, Joseph D. Smith
Publikováno v:
Infection and Immunity. 76:1791-1800
Pregnancy-associated malaria (PAM) is characterized by the placental sequestration of Plasmodium falciparum -infected erythrocytes (IEs) with the ability to bind to chondroitin sulfate A (CSA). VAR2CSA is a leading candidate for a pregnancy malaria v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b97cfec9d35f9e1ce3c449a8731e198
https://doi.org/10.1128/iai.01470-07
https://doi.org/10.1128/iai.01470-07
Autor:
Karine Reiter, Vu Nguyen, Yimin Wu, Albert J. Jin, Beth Chen, Krishan Kumar, Kelly M. Rausch, Christopher G. Rowe, David L. Narum, Joan Aebig, Richard L. Shimp, David S. Jones
Successful efforts to control infectious diseases have often required the use of effective vaccines. The current global strategy for control of malaria, including elimination and eradication will also benefit from the development of an effective vacc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f67515500597d3014d4a516f3f45db7
https://europepmc.org/articles/PMC3683851/
https://europepmc.org/articles/PMC3683851/
Autor:
Karine Reiter, David S. Jones, David L. Narum, Beth Chen, Yimin Wu, Patrick E. Duffy, Kelly M. Rausch, Christopher G. Rowe
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0138761 (2016)
PLoS ONE, Vol 11, Iss 3, p e0138761 (2016)
A practical method is described for synthesizing conjugated protein nanoparticles using thioether (thiol-maleimide) cross-linking chemistry. This method fills the need for a reliable and reproducible synthesis of protein conjugate vaccines for precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d0e70915bcc7e671a7a4a4df05c958
https://doi.org/10.1371/journal.pone.0138761
https://doi.org/10.1371/journal.pone.0138761
Autor:
Louis H. Miller, David S. Jones, Feng Qian, Daming Zhu, Allan Saul, Yimin Wu, Patrick E. Duffy, Christopher G. Rowe, David L. Narum
The present study reports a method to determine the total protein concentration or concentration of a protein of interest in a protein-protein conjugate using ultraviolet absorption, after determining the molar ratio of proteins in the conjugates, fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffe7214d1e327b112b588390e659eb2
https://europepmc.org/articles/PMC3529773/
https://europepmc.org/articles/PMC3529773/