Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Christopher G England"'
Autor:
Christopher G England, Justin S Huang, Kurtis T James, Guandong Zhang, André M Gobin, Hermann B Frieboes
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129172 (2015)
Nanoparticle uptake and distribution to solid tumors are limited by reticuloendothelial system systemic filtering and transport limitations induced by irregular intra-tumoral vascularization. Although vascular enhanced permeability and retention can
Externí odkaz:
https://doaj.org/article/632c3dd6d5694709a6aa3a7a59f2899c
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003231 (2013)
A clear contradiction exists between cytotoxic in-vitro studies demonstrating effectiveness of Gemcitabine to curtail pancreatic cancer and in-vivo studies failing to show Gemcitabine as an effective treatment. The outcome of chemotherapy in metastat
Externí odkaz:
https://doaj.org/article/f7cf1236a17e4ce5b4e9dccba496877c
Autor:
Weibo Cai, Robert J. Nickles, Hing C. Wong, Charles P. Theuer, Bai Liu, Reinier Hernandez, Stephen A. Graves, Sixiang Shi, Christopher G. England, Haiming Luo
Supplementary Figure 1. Purification of heterodimer after click chemistry conjugation of ALT-836-Fab and TRC105-Fab Supplementary Figure 2. MALDI-TOF mass spectra of ALT-836-Fab: [M+H]+ = 47266.0, TRC105-Fab: [M+H]+ = 47454.7, and heterodimer: exact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aeaf1a03ca3e3aa1fc0c7fba1c47be
https://doi.org/10.1158/1078-0432.22457511
https://doi.org/10.1158/1078-0432.22457511
Autor:
Weibo Cai, Robert J. Nickles, Hing C. Wong, Charles P. Theuer, Bai Liu, Reinier Hernandez, Stephen A. Graves, Sixiang Shi, Christopher G. England, Haiming Luo
Movie S3 from Dual Targeting of Tissue Factor and CD105 for Preclinical PET Imaging of Pancreatic Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2c396bffc21ab00d2219ac18c6d29f
https://doi.org/10.1158/1078-0432.22457514
https://doi.org/10.1158/1078-0432.22457514
Autor:
Weibo Cai, Robert J. Nickles, Hing C. Wong, Charles P. Theuer, Bai Liu, Reinier Hernandez, Stephen A. Graves, Sixiang Shi, Christopher G. England, Haiming Luo
Determination of NOTA to Fab Fragment Ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9e2b597f00e46e64162d667747e2a1
https://doi.org/10.1158/1078-0432.22457508.v1
https://doi.org/10.1158/1078-0432.22457508.v1
Data from Dual Targeting of Tissue Factor and CD105 for Preclinical PET Imaging of Pancreatic Cancer
Autor:
Weibo Cai, Robert J. Nickles, Hing C. Wong, Charles P. Theuer, Bai Liu, Reinier Hernandez, Stephen A. Graves, Sixiang Shi, Christopher G. England, Haiming Luo
Purpose: Pancreatic adenocarcinoma is a highly aggressive cancer, currently treated with limited success and dismal outcomes. New diagnostic and treatment strategies offer the potential to reduce cancer mortality. Developing highly specific noninvasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066fc9ff527929c8d08cbb8079bf586c
https://doi.org/10.1158/1078-0432.c.6523599.v1
https://doi.org/10.1158/1078-0432.c.6523599.v1
Autor:
Christopher G England
Publikováno v:
Physiology. 37:54-54
Autor:
Christopher G. England, Dawei Jiang, Hyung Jun Im, Xiaoli Lan, Dalong Ni, Peng Huang, Lei Kang, Weibo Cai, Jonathan W. Engle, Madeline E Boleyn
Publikováno v:
Nano Research. 12:637-642
DNA tetrahedron nanostructure (DTN) is one of the simplest DNA nanostructures and has been successfully applied for biosensing, imaging, and treatment of cancer. To facilitate its biomedical applications and potential clinical translation, fundamenta
Autor:
Christopher G. England, Hao Yan, Zhilei Ge, Dawei Jiang, Christopher J. Kutyreff, Yan Liu, Steve Y. Cho, Peng Huang, Chunhai Fan, Junjun Hou, Hyung Jun Im, Jiye Shi, Dalong Ni, Weibo Cai, Jonathan W. Engle, Luhao Zhang, Yongjun Yan
Publikováno v:
Nature Biomedical Engineering. 2:865-877
Patients with acute kidney injury (AKI) frequently require kidney transplantation and supportive therapies, such as rehydration and dialysis. Here, we show that radiolabelled DNA origami nanostructures (DONs) with rectangular, triangular and tubular
Autor:
Emily K. Jeng, Terra Noel, Sarah Alter, Bai Liu, Lin Kong, Jeffrey S. Miller, Weibo Cai, Sixiang Shi, Christopher G. England, Peter R. Rhode, Hing C. Wong, Monica Brown Jones
Publikováno v:
Cytokine. 107:105-112
ALT-803 is a fusion protein complex consisting of an interleukin (IL)-15 superagonist and a dimeric IL-15 receptor alpha sushi domain IgG1 Fc fusion protein. When administered to mice, ALT-803 is capable of inducing natural killer (NK) and CD8(+) T c