Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Christopher G, Rylander"'
Autor:
Josefa Karina Garcia Mora, John Robertson, Fang‐Chi Hsu, Richard Levon Shinn, Martha M. Larson, Christopher G. Rylander, Christopher T. Whitlow, Waldemar Debinski, Rafael V. Davalos, Gregory B.Daniel, John H. Rossmeisl
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 1066-1074 (2022)
Abstract Background Brain tumor therapeutic responses can be quantified from magnetic resonance images (MRI) using 1‐ (1D) and 2‐dimensional (2D) linear and volumetric methods, but few studies in dogs compare these techniques. Hypotheses Linear m
Externí odkaz:
https://doaj.org/article/f4d652b4971a4d93886f9099f6e9b26f
Autor:
Brittanie Partridge, Allison Eardley, Brianna E. Morales, Sabrina N. Campelo, Melvin F. Lorenzo, Jason N. Mehta, Yukitaka Kani, Josefa K. Garcia Mora, Etse-Oghena Y. Campbell, Christopher B. Arena, Simon Platt, Akiva Mintz, Richard L. Shinn, Christopher G. Rylander, Waldemar Debinski, Rafael V. Davalos, John H. Rossmeisl
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The blood-brain barrier (BBB) presents a formidable obstacle to the effective delivery of systemically administered pharmacological agents to the brain, with ~5% of candidate drugs capable of effectively penetrating the BBB. A variety of biomaterials
Externí odkaz:
https://doaj.org/article/4dd41ae5e6864af2948892771284a5a7
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 753 (2020)
The standard of care for treatment of glioblastoma results in a mean survival of only 12 to 15 months. Convection-enhanced delivery (CED) is an investigational therapy to treat glioblastoma that utilizes locoregional drug delivery via a small-caliber
Externí odkaz:
https://doaj.org/article/e6718d75aa0745f989bd0977925a7638
Publikováno v:
Engineering, Vol 1, Iss 3, Pp 344-350 (2015)
Convection-enhanced delivery (CED) is a promising technique leveraging pressure-driven flow to increase penetration of infused drugs into interstitial spaces. We have developed a fiberoptic microneedle device for inducing local sub-lethal hyperthermi
Externí odkaz:
https://doaj.org/article/1c199888a67f4f69a8e33bdffa4e2808
Autor:
Jason N, Mehta, Brianna E, Morales, John H, Rossmeisl, Waldemar, Debinski, Christopher G, Rylander
Publikováno v:
Journal of Medical Devices. 16
Convection-enhanced delivery (CED) is a drug delivery technique used to deliver therapeutics directly to the brain and is a continually evolving technique to treat glioblastoma. Early versions of CED have proven to result in inadequate drug volume di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd3c9376685066b481a5c6b23facf69
https://doi.org/10.1115/1.4055607
https://doi.org/10.1115/1.4055607
Convection-enhanced delivery with controlled catheter movement: A parametric finite element analysis
Publikováno v:
International journal for numerical methods in biomedical engineering. 38(9)
Convection-enhanced delivery (CED) is an investigational method for delivering therapeutics directly to the brain for the treatment of glioblastoma. However, it has not become a common clinical therapy due to an inability of CED treatments to deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed313db729c10bad72326d84256c4646
https://pubmed.ncbi.nlm.nih.gov/35763587
https://pubmed.ncbi.nlm.nih.gov/35763587
Publikováno v:
2022 Design of Medical Devices Conference.
The Convection-Enhanced Thermo-Therapy Catheter System (CETCS) was developed by our group at The University of Texas at Austin for the treatment of glioblastoma. This arborizing catheter is remotely operated and provides the ability to position and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e68c413dc9ab98d17f916916a884dc
https://doi.org/10.1115/dmd2022-1067
https://doi.org/10.1115/dmd2022-1067
Publikováno v:
2022 Design of Medical Devices Conference.
Convection-enhanced delivery (CED) is an emerging method for treating highly aggressive and infiltrative forms of brain cancer, like glioblastomas. However, drawbacks of utilizing CED include limited availability of tools capable of bypassing the blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec8e91658cee6fd6151bfd6ffbfb38a
https://doi.org/10.1115/dmd2022-1057
https://doi.org/10.1115/dmd2022-1057
Autor:
Iman Salafian, Christopher G. Rylander
Publikováno v:
2022 Design of Medical Devices Conference.
Convection-enhanced delivery (CED) through an arborizing microneedle catheter system is an experimental drug delivery technique used to treat glioblastoma by providing a higher drug volume dispersed (Vd) of therapeutics directly to larger regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91df6e306d7e4f8d443cf6268e187d6a
https://doi.org/10.1115/dmd2022-1060
https://doi.org/10.1115/dmd2022-1060
Publikováno v:
Journal of biomechanical engineering. 144(11)
Convection-enhanced delivery (CED) has been extensively studied for drug delivery to the brain due to its inherent ability to bypass the blood-brain barrier. Unfortunately, CED has also been shown to inadequately distribute therapeutic agents over a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc571165dc64a5ebd0ca31aa07737a1b
https://pubmed.ncbi.nlm.nih.gov/35656789
https://pubmed.ncbi.nlm.nih.gov/35656789