Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Christopher G, Ellis"'
Autor:
Laura Mawdsley, Rasa Eskandari, Farah Kamar, Ajay Rajaram, Lawrence C. M. Yip, Naomi Abayomi, Stephanie Milkovich, Jeffrey J. L. Carson, Keith St. Lawrence, Christopher G. Ellis, Mamadou Diop
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 9, Pp 390-399 (2024)
Abstract This study aimed to investigate the simultaneous response of the cerebral and skeletal muscle microvasculature to the same phenylephrine (PE) boluses. A hybrid optical system that combines hyperspectral near‐infrared spectroscopy (hs‐NIR
Externí odkaz:
https://doaj.org/article/ab9e4c9885084c7d9d7f394de29c8246
Autor:
Paulina M. Kowalewska, Justin E. Piazza, Stephanie L. Milkovich, Richard J. Sové, Lin Wang, Shawn N. Whitehead, Christopher G. Ellis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Sepsis is a dysregulated host inflammatory response to infection potentially leading to life-threatening organ dysfunction. The objectives of this study were to determine whether early microvascular dysfunction (MVD) in skeletal muscle can b
Externí odkaz:
https://doaj.org/article/2882ed0426464ea382735ea599cf8c8a
Autor:
Asher A. Mendelson, Casey Lansdell, Alison E. Fox-Robichaud, Patricia Liaw, Jaskirat Arora, Jean-François Cailhier, Gediminas Cepinskas, Emmanuel Charbonney, Claudia dos Santos, Dhruva Dwivedi, Christopher G. Ellis, Dean Fergusson, Kirsten Fiest, Sean E. Gill, Kathryn Hendrick, Victoria T. Hunniford, Paulina M. Kowalewska, Karla Krewulak, Christian Lehmann, Kimberly Macala, John C. Marshall, Laura Mawdsley, Braedon McDonald, Ellen McDonald, Sarah K. Medeiros, Valdirene S. Muniz, Marcin Osuchowski, Justin Presseau, Neha Sharma, Sahar Sohrabipour, Janet Sunohara-Neilson, Gloria Vázquez-Grande, Ruud A. W. Veldhuizen, Donald Welsh, Brent W. Winston, Ryan Zarychanski, Haibo Zhang, Juan Zhou, Manoj M. Lalu, Sepsis Canada’s National Preclinical Sepsis Platform
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Despite decades of preclinical research, no experimentally derived therapies for sepsis have been successfully adopted into routine clinical practice. Factors that contribute to this crisis of translation include poor representation by precl
Externí odkaz:
https://doaj.org/article/9aeed005c2d54e4888a280f7bf96c4a3
Autor:
Richard J. Sové, Stephanie Milkovich, Hristo N. Nikolov, David W. Holdsworth, Christopher G. Ellis, Graham M. Fraser
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Intravital microscopy has proven to be a powerful tool for studying microvascular physiology. In this study, we propose a gas exchange system compatible with intravital microscopy that can be used to impose gas perturbations to small localized region
Externí odkaz:
https://doaj.org/article/70ecfcf1926a4c18ad857b6c0f1ff4b9
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Background: Ischemic and hyperemic injury have emerged as biologic mechanisms that contribute to cognitive impairment in critically ill patients. Spontaneous deviations in cerebral blood flow (CBF) beyond ischemic and hyperemic thresholds may represe
Externí odkaz:
https://doaj.org/article/dea20e748710497998fbe12177ca4336
Role and Molecular Mechanisms of Pericytes in Regulation of Leukocyte Diapedesis in Inflamed Tissues
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Leukocyte recruitment is a hallmark of the inflammatory response. Migrating leukocytes breach the endothelium along with the vascular basement membrane and associated pericytes. While much is known about leukocyte-endothelial cell interactions, the m
Externí odkaz:
https://doaj.org/article/b32b6cea9a7442b08a9b31e33074ab57
Autor:
Asher A. Mendelson, Edward Ho, Shayla Scott, Raashi Vijay, Timothy Hunter, Stephanie Milkovich, Christopher G. Ellis, Daniel Goldman
Publikováno v:
The Journal of Physiology. 600:1867-1888
The capillary module (CM), consisting of parallel capillaries from terminal arteriole to post-capillary venule, is classically considered to be the building block of complex capillary networks. In skeletal muscle, CMs form interconnected columns span
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6446b0f96ad62057bc7d962b1235dce
https://doi.org/10.1113/jp282342
https://doi.org/10.1113/jp282342
Autor:
Sean E. Gill, Ellen McDonald, Christian Lehmann, Victoria T. Hunniford, Marcin F. Osuchowski, Karla D. Krewulak, Asher A. Mendelson, Janet Sunohara-Neilson, Manoj M. Lalu, Gloria Vazquez-Grande, Kathryn Hendrick, Christopher G. Ellis, John Marshall, Sarah K. Medeiros, Sahar Sohrabipour, Dean Fergusson, Dhruva J. Dwivedi, Neha Sharma, Haibo Zhang, Kirsten M. Fiest, Claudia C. dos Santos, Laura Mawdsley, Jaskirat Arora, Gediminas Cepinskas, Alison Fox-Robichaud, Jean-François Cailhier, Patricia C. Liaw, Ryan Zarychanski, Kimberly F. Macala, Brent W. Winston, Valdirene S Muniz, Ruud A. W. Veldhuizen, Justin Presseau, Emmanuel Charbonney, Casey Lansdell, Donald G. Welsh, Juan Zhou, Paulina M. Kowalewska, Braedon McDonald
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-19 (2021)
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental
Despite decades of preclinical research, no experimentally derived therapies for sepsis have been successfully adopted into routine clinical practice. Factors that contribute to this crisis of translation include poor representation by preclinical mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ea41fbe1b9f37c1a9f896f76a095d9
https://doaj.org/article/9aeed005c2d54e4888a280f7bf96c4a3
https://doaj.org/article/9aeed005c2d54e4888a280f7bf96c4a3
Autor:
Mohammed A. El‐Lakany, Paulina M. Kowalewska, Shaun L. Sandow, Christopher G. Ellis, Donald G. Welsh
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f240db8cad5bd6448f5d3796adadfd
https://doi.org/10.1096/fasebj.2022.36.s1.r3060
https://doi.org/10.1096/fasebj.2022.36.s1.r3060
Autor:
Paulina M. Kowalewska, Stephanie L. Milkovich, Daniel Goldman, Shaun L. Sandow, Christopher G. Ellis, Donald G. Welsh
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663a78342fcbaff6948e7ddf59e97654
https://doi.org/10.1096/fasebj.2022.36.s1.r5038
https://doi.org/10.1096/fasebj.2022.36.s1.r5038