Výsledky vyhledávání - "Christopher Finan"

Akademický článek

Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)

Isolated populations often have special genetic compositions that can be leveraged for genetic association studies. Here, Xue and colleagues generate and analyse 3,059 low-depth whole-genome sequences from eight European isolated populations and two

Externí odkaz: https://doaj.org/article/09e63dea89244cb9bf890f07177b88d2

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Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney

Autor: Ingrid Wise, Bradley Godfrey, Raymond T. O'Keefe, Mikael Ekholm, Wojciech Wystrychowski, Pasquale Maffia, Matthias Kretzler, Sushant Saluja, James Eales, Artur Akbarov, Christopher Finan, Maciej Tomaszewski, Monika Szulińska, Gosia Trynka, Matthew Denniff, Sanjeev Pramanik, Ewa Zukowska-Szczechowska, Bernard Keavney, Andrew P. Morris, Yusif Shakanti, Sandesh Chopade, John Bowes, Eddie Cano-Gamez, Huw B. Thomas, Matthew G. Sampson, Xiaoguang Xu, Evangelos Evangelou, Paweł Bogdański, Priscilla R. Prestes, Stephen Eyre, Xiao Jiang, David Talavera, Fadi J. Charchar, Hui Guo, Andrzej Antczak, Joanna Zywiec, Nilesh J. Samani, Alicja Nazgiewicz, Michelle T. McNulty, Adrian S. Woolf, Robert Król, Tomasz J. Guzik, Jason Brown, Carlo Berzuini, Mahan Salehi, Maciej Glyda, Aroon D. Hingorani, Felix Eichinger, Mark J. Caulfield

Publikováno v: Nature Genetics
Eales, J, Jiang, X, Xu, X, Saluja, S, Akbarov, A, Cano-Gomez, E, McNulty, M T, Finan, C, Guo, H, Wystrychowski, W, Szulinska, M, Thomas, H, Pramanik, S, Chopade, S, Prestes, P R, Wise, I, Evangelou, E, Salehi, M, Shakanti, Y, Ekholm, M, Denniff, M, Nazgiewicz, A, Eichinger, F, Godfrey, B, Antczak, A, Glyda, M, Król, R, Eyre, S, Brown, J, Berzuini, C, Bowes, J, Caulfield, M, Zukowska-Szczechowska, E, Zywiec, J, Bogdanski, P, Kretzler, M, Woolf, A S, Talavera, D, Keavney, B, Maffia, P, Guzik, T J, O'Keefe, R, Trynka, G, Samani, N J, Hingorani, A D, Sampson, M G, Morris, A P, Charchar, F J, Tomaszewski, M & Morris, A 2021, ' Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney ', Nature Genetics, vol. 53, no. 5, pp. 630–637 . https://doi.org/10.1038/s41588-021-00835-w

The kidney is an organ of key relevance to blood pressure (BP) regulation, hypertension and antihypertensive treatment. However, genetically mediated renal mechanisms underlying susceptibility to hypertension remain poorly understood. We integrated g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2155ee0f1aed73a8a73ac6151d01c4a

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Elektronická kniha

Drunks : An American History

Autor: Christopher Finan

BOOZE AND ITS DISCONTENTS: Explore the history of the United States'struggle with alcoholism—and the emergence of a search for sobriety as old as our nation. “An interesting read for fans of American history.” —Library Journal Christopher Fin

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Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

Publikováno v: Xue, Y, Mezzavilla, M, Haber, M, McCarthy, S, Chen, Y, Narasimhan, V, Gilly, A, Ayub, Q, Colonna, V, Southam, L, Finan, C, Massaia, A, Chheda, H, Palta, P, Ritchie, G, Asimit, J, Dedoussis, G, Gasparini, P, Palotie, A, Ripatti, S, Soranzo, N, Daniela, T, Wilson, J, Durbin, R, Tyler-Smith, C & Zeggini, E 2017, ' Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations ', Nature Communications . https://doi.org/10.1038/ncomms15927
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications
Nature communications 8 (2017). doi:10.1038/ncomms15927
info:cnr-pdr/source/autori:Xue, Yali; Mezzavilla, Massimo; Haber, Marc; McCarthy, Shane; Chen, Yuan; Narasimhan, Vagheesh; Gilly, Arthur; Ayub, Qasim; Colonna, Vincenza; Southam, Lorraine; Finan, Christopher; Massaia, Andrea; Chheda, Himanshu; Palta, Priit; Ritchie, Graham; Asimit, Jennifer; Dedoussis, George; Gasparini, Paolo; Palotie, Aarno; Ripatti, Samuli; Soranzo, Nicole; Toniolo, Daniela; Wilson, James F.; Durbin, Richard; Tyler-Smith, Chris; Zeggini, Eleftheria/titolo:Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations/doi:10.1038%2Fncomms15927/rivista:Nature communications/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:8

The genetic features of isolated populations can boost power in complex-trait association studies, and an in-depth understanding of how their genetic variation has been shaped by their demographic history can help leverage these advantageous characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214290936e31d075b8a2a28055ceefca
https://hdl.handle.net/20.500.11820/68cb1dde-2ab9-4bef-897f-9f80de0be2ca

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Adaptive evolution of nontransgenic Escherichia coli KC01 for improved ethanol tolerance and homoethanol fermentation from xylose

Autor: Jinhua Wang, Shengde Zhou, Christopher Finan, Ryan Manow, Yongze Wang, Erin Garza

Publikováno v: Journal of Industrial Microbiology & Biotechnology. 38:1371-1377

Due to its excellent capability to ferment five-carbon sugars, Escherichia coli has been considered one of the platform organisms to be engineered for production of cellulosic ethanol. Nevertheless, genetically engineered ethanologenic E. coli lacks

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af1da7969d94a40fd4725de10f83216
https://doi.org/10.1007/s10295-010-0920-5

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