Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher Fife"'
Autor:
Vichithranie W. Madurasinghe, Peter Knapp, Sandra Eldridge, David Collier, Shaun Treweek, Jo Rick, Jonathan Graffy, Adwoa Parker, Chris Salisbury, David Torgerson, Kate Jolly, Manbinder S. Sidhu, Christopher Fife-Schaw, Mark A. Hull, Kirsty Sprange, Elizabeth Brettell, Sunil Bhandari, Alan Montgomery, Peter Bower
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background People need high-quality information to make decisions about research participation. Providing information in written format alone is conventional but may not be the most effective and acceptable approach. We developed a structure
Externí odkaz:
https://doaj.org/article/fd634550dd654aca86a6535cb020f0e6
Autor:
Ashley Sunderland, Jennifer Williams, Tereza Andreou, Nora Rippaus, Christopher Fife, Fiona James, Yolanda Dyah Kartika, Valerie Speirs, Ian Carr, Alastair Droop, Mihaela Lorger
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Exit of quiescent disseminated cancer cells from dormancy is thought to be responsible for metastatic relapse and a better understanding of dormancy could pave the way for novel therapeutic approaches. We used an in vivo model of triple negative brea
Externí odkaz:
https://doaj.org/article/edd0e15041a74a878fd5719f0821bcfc
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Immune checkpoints restrain the immune system following its activation and their inhibition unleashes anti-tumor immune responses. Immune checkpoint inhibitors revolutionized the treatment of several cancer types, including melanoma, and immune check
Externí odkaz:
https://doaj.org/article/011e7833f36e4efb9fbab3a7c1a8c0f1
Autor:
Anita Ayer, Sina Fellermeier, Christopher Fife, Simone S Li, Gertien Smits, Andreas J Meyer, Ian W Dawes, Gabriel G Perrone
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44278 (2012)
Maintenance of an optimal redox environment is critical for appropriate functioning of cellular processes and cell survival. Despite the importance of maintaining redox homeostasis, it is not clear how the optimal redox potential is sensed and set, a
Externí odkaz:
https://doaj.org/article/2f771b4bb11548bd873bc2ad942011d1
Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters
Autor:
Ryan K. Mathew, Ashley Sunderland, Alastair Droop, Christopher Fife, Jennifer Williams, Nora Rippaus, Stephanie Cherqui, Tereza Andreou, Teklu Egnuni, Yolanda D Kartika, David Taggart, Sheri L. Holmen, Krzysztof Wronski, Mihaela Lorger, Rebecca J Brownlie
Publikováno v:
Journal of the National Cancer Institute, vol 112, iss 6
JNCI Journal of the National Cancer Institute
JNCI Journal of the National Cancer Institute
Background Brain metastases (BrM) develop in 20–40% of cancer patients and represent an unmet clinical need. Limited access of drugs into the brain because of the blood-brain barrier is at least partially responsible for therapeutic failure, necess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178f78babaaa5617b246e0933bdf62fa
https://doi.org/10.1093/jnci/djz181
https://doi.org/10.1093/jnci/djz181
Autor:
Robert J Salmond, Rebecca J Brownlie, Mihaela Lorger, Tereza Andreou, Christopher Fife, S R Gregory, F James, H Carrasco Hope, J Newton-Bishop, Jennifer Williams
Publikováno v:
Neuro Oncol
BACKGROUND Up to 60% of melanoma patients develop brain metastases (BrM). These patients have a poor prognosis and limited treatment options. Immune checkpoint inhibitors (ICI) targeting Cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) and Progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067c5dd6b7dcb2f1b300c3896832d665
https://doi.org/10.1093/neuonc/noab180.089
https://doi.org/10.1093/neuonc/noab180.089
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Immune checkpoints restrain the immune system following its activation and their inhibition unleashes anti-tumor immune responses. Immune checkpoint inhibitors revolutionized the treatment of several cancer types, including melanoma, and immune check
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5443895a8c64fcd447f3807bc88f47da
https://eprints.whiterose.ac.uk/153271/1/fnmol-12-00282.pdf
https://eprints.whiterose.ac.uk/153271/1/fnmol-12-00282.pdf
Autor:
Jennifer Williams, Mihaela Lorger, Robert J Salmond, A Sunderland, C McKimmie, Christopher Fife, Tereza Andreou, Rebecca J Brownlie
Publikováno v:
Ashley Sunderland
Neuro Oncol
Neuro Oncol
BACKGROUND Brain metastases (BrM) are an unmet clinical need with poor prognosis. 60% of melanoma patients develop BrM. BrM are strongly understudied due to frequent exclusion from clinical trials, and hence treatment options commonly lag behind. Ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b739ab5224d8d0c5052dcc0c529a81
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427398/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427398/?tool=EBI