Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christopher F. Theriau"'
Autor:
Christopher F Theriau, O'Llenecia S Sauvé, Marie-Soleil Beaudoin, David C Wright, Michael K Connor
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183897 (2017)
Obesity is clearly associated with an increased risk of breast cancer in postmenopausal women. The purpose was to determine if obesity alters the adipocyte adipokine secretion profile, thereby altering the adipose-dependent paracrine/endocrine growth
Externí odkaz:
https://doaj.org/article/6da199f459da43fca84241f5826776e0
Autor:
Christopher F. Theriau, Jamie Feng, Lawson Eng, Frances A. Shepherd, Mary DeCarolis, Vivian Glenns, Swati Kulkarni, Rachel VanderMeer, Urszula Zurawska-Fortin, Desiree Hao, Lisa Le, Isabel Wozniczka, Aida Al-Kindy, Danny Xie, Tong Zhang, Vasanth Subramanian, Tracy Stockley, Penelope A. Bradbury, Geoffrey Liu, Natasha B. Leighl
Publikováno v:
Cancer Research. 83:CT206-CT206
Introduction: MEK inhibition combined with PD-1 axis inhibition may achieve a greater clinical response than either inhibitor alone due to increased T-cell infiltration of tumours. We combined binimetinib with pembrolizumab in patients with stage IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6e205008903237b169db30b682f51f7
https://doi.org/10.1158/1538-7445.am2023-ct206
https://doi.org/10.1158/1538-7445.am2023-ct206
Autor:
Ali C. Dehghani, Christopher G. R. Perry, Christopher F. Theriau, Patrick C. Turnbull, Michael K. Connor
Publikováno v:
Am J Physiol Cell Physiol
Fatty acid stress can have divergent effects in various cancers. We explored how metabolic and redox flexibility in HepG2 hepatocarcinoma cells mediates protection from palmitoylcarnitine. HepG2 cells, along with HCT 116 and HT29 colorectal cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687313aa32b6691d67e88881f2a03a77
https://pubmed.ncbi.nlm.nih.gov/31618075
https://pubmed.ncbi.nlm.nih.gov/31618075
Publikováno v:
Journal of Applied Physiology. 121:139-153
The molecular mechanisms behind the obesity-breast cancer association may be regulated via adipokine secretion by white adipose tissue. Specifically, adiponectin and leptin are altered with adiposity and exert antagonistic effects on cancer cell prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746fc9886bf5db538a9337ada49ec8ff
https://doi.org/10.1152/japplphysiol.00862.2015
https://doi.org/10.1152/japplphysiol.00862.2015
Publikováno v:
Physiological Reports
The adipokine secretion profile created from adipose tissue may represent the molecular mechanism behind the obesity‐breast cancer association. Two adipokines, adiponectin (ADIPO), and leptin (LEP), are altered with obesity and exert antagonistic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d2efb31eea25df24ae011e85677651
http://europepmc.org/articles/PMC5506521
http://europepmc.org/articles/PMC5506521
Autor:
Michael K. Connor, O’Llenecia S. Sauvé, David C. Wright, Marie-Soleil Beaudoin, Christopher F. Theriau
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0183897 (2017)
PLoS ONE, Vol 12, Iss 9, p e0183897 (2017)
Obesity is clearly associated with an increased risk of breast cancer in postmenopausal women. The purpose was to determine if obesity alters the adipocyte adipokine secretion profile, thereby altering the adipose-dependent paracrine/endocrine growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e0113231681aa06e6b738761c7f54
https://doi.org/10.1371/journal.pone.0183897
https://doi.org/10.1371/journal.pone.0183897
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c66abd4c8e28c8ba01f868ea6f51f7
https://doi.org/10.1096/fasebj.27.1_supplement.1027.6
https://doi.org/10.1096/fasebj.27.1_supplement.1027.6