Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christopher F Mugler"'
Autor:
Ruchika Sachdev, Maria Hondele, Miriam Linsenmeier, Pascal Vallotton, Christopher F Mugler, Paolo Arosio, Karsten Weis
Publikováno v:
eLife, Vol 8 (2019)
Processing bodies (PBs) are cytoplasmic mRNP granules that assemble via liquid–liquid phase separation and are implicated in the decay or storage of mRNAs. How PB assembly is regulated in cells remains unclear. Previously, we identified the ATPase
Externí odkaz:
https://doaj.org/article/b257437cc5c34c31bc3e75eac4b85c39
Publikováno v:
eLife, Vol 7 (2018)
The cytoplasmic abundance of mRNAs is strictly controlled through a balance of production and degradation. Whereas the control of mRNA synthesis through transcription has been well characterized, less is known about the regulation of mRNA turnover, a
Externí odkaz:
https://doaj.org/article/0592d1f03bd34bcf86d26738ce4b5c7f
Autor:
Pascal Vallotton, Maria Hondele, Ruchika Sachdev, Miriam Linsenmeier, Paolo Arosio, Karsten Weis, Christopher F Mugler
Publikováno v:
eLife, Vol 8 (2019)
eLife, 8
eLife
eLife, 8
eLife
Processing bodies (PBs) are cytoplasmic mRNP granules that assemble via liquid–liquid phase separation and are implicated in the decay or storage of mRNAs. How PB assembly is regulated in cells remains unclear. Previously, we identified the ATPase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8298d970f7c428c7b824bd10edb301e2
https://elifesciences.org/articles/41415
https://elifesciences.org/articles/41415
Autor:
Leon Y. Chan, Pascal Vallotton, Annemarie Kralt, Carina Patrizia Derrer, Thomas U. Schwartz, Karsten Weis, Jeffrey H Tang, Evgeny Onischenko, Christopher F Mugler, Kevin E. Knockenhauer, Kasper R. Andersen
Publikováno v:
Cell, 171 (4)
Onischenko, E, Tang, J H, Andersen, K R, Knockenhauer, K E, Vallotton, P, Derrer, C P, Kralt, A, Mugler, C F, Chan, L Y, Schwartz, T U & Weis, K 2017, ' Natively Unfolded FG Repeats Stabilize the Structure of the Nuclear Pore Complex ', Cell, vol. 171, no. 4, pp. 904-917 . https://doi.org/10.1016/j.cell.2017.09.033
PMC
Onischenko, E, Tang, J H, Andersen, K R, Knockenhauer, K E, Vallotton, P, Derrer, C P, Kralt, A, Mugler, C F, Chan, L Y, Schwartz, T U & Weis, K 2017, ' Natively Unfolded FG Repeats Stabilize the Structure of the Nuclear Pore Complex ', Cell, vol. 171, no. 4, pp. 904-917 . https://doi.org/10.1016/j.cell.2017.09.033
PMC
Nuclear pore complexes (NPCs) are ∼100 MDa transport channels assembled from multiple copies of ∼30 nucleoporins (Nups). One-third of these Nups contain phenylalanine-glycine (FG)-rich repeats, forming a diffusion barrier, which is selectively pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b50f94b80f579f0632e86fff1a8ad
https://hdl.handle.net/20.500.11850/207204
https://hdl.handle.net/20.500.11850/207204
Autor:
Leon Y. Chan, Pascal Vallotton, Adriana Y Koek, Christopher F Mugler, Karsten Weis, Maria Hondele, Stephanie Heinrich, Ruchika Sachdev
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife, 5
eLife
eLife, 5
Translational repression and mRNA degradation are critical mechanisms of posttranscriptional gene regulation that help cells respond to internal and external cues. In response to certain stress conditions, many mRNA decay factors are enriched in proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0d6f44698706e5f3bd0dfc43aca42d
https://elifesciences.org/articles/18746
https://elifesciences.org/articles/18746
Autor:
Christopher F Mugler, Karsten Weis, Adriana Y Koek, Maria Hondele, Pascal Vallotton, Leon Y. Chan, Ruchika Sachdev, Stephanie Heinrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbdca5c37d30a0ee0d5e126a79a74218
https://doi.org/10.7554/elife.18746.030
https://doi.org/10.7554/elife.18746.030
Autor:
Karsten Weis, Philipp Mertins, Marko Jovanovic, Aviv Regev, Leon Y. Chan, Ze Cheng, Gloria A. Brar, Abdurrahman Keskin, Stefanie Hodapp, Christopher F Mugler
Publikováno v:
Molecular Cell, 73 (1)
PMC
Molecular cell, vol 73, iss 1
PMC
Molecular cell, vol 73, iss 1
In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cbdfe631971f03ead27b8f9a2a84014
https://doi.org/10.1016/j.molcel.2018.10.032
https://doi.org/10.1016/j.molcel.2018.10.032
Autor:
Dezhi Mu, Brian Matsumoto, Qiang Gong, Christopher F Mugler, Marc Zimmermann, Dzwokai Ma, Benjamin Groves, Matthew N.J. Seaman, Bin Xia, Zhuojin Xu
Publikováno v:
The Journal of Cell Biology
Histone lysine methyltransferase complexes are essential for chromatin organization and gene regulation. Whether any of this machinery functions in membrane traffic is unknown. In this study, we report that mammal Dpy-30 (mDpy-30), a subunit of sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b6ca5d65c1cbff730871300181e72d
https://doi.org/10.1083/jcb.200902146
https://doi.org/10.1083/jcb.200902146