Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Christopher F, Thompson"'
Autor:
Prasanthi Geda, Mark A. McCoy, Liping Yang, Chaomin Li, Armetta D. Hill, Xavier Fradera, Marianne L. Spatz, Matthew Ernst Voss, Carolyn Michele Cammarano, Pierre Daublain, Xiao Wang, Christopher F. Thompson, B. Wesley Trotter, C. Gary Marshall, Michael H. Reutershan, Peter Goldenblatt, Latha G. Nair, Manami Shizuka, Tammie C. Yeh, John G. Cryan, Isabelle Dussault, Michelle Martinez, Mingmei Cai, Raymond A. Kemper, Binyuan Sun, Michelle R. Machacek, Dietrich Steinhuebel, Giovanna Scapin, Michael D. Altman, Stephane L. Bogen, Matthew Christopher, Dapeng Chen, Victoria Kutilek, Weidong Pan
Publikováno v:
Journal of Medicinal Chemistry. 64:16213-16241
Identification of low-dose, low-molecular-weight, drug-like inhibitors of protein-protein interactions (PPIs) is a challenging area of research. Despite the challenges, the therapeutic potential of PPI inhibition has driven significant efforts toward
Autor:
Michael H, Reutershan, Michelle R, Machacek, Michael D, Altman, Stephane, Bogen, Mingmei, Cai, Carolyn, Cammarano, Dapeng, Chen, Matthew, Christopher, John, Cryan, Pierre, Daublain, Xavier, Fradera, Prasanthi, Geda, Peter, Goldenblatt, Armetta D, Hill, Raymond A, Kemper, Victoria, Kutilek, Chaomin, Li, Michelle, Martinez, Mark, McCoy, Latha, Nair, Weidong, Pan, Christopher F, Thompson, Giovanna, Scapin, Manami, Shizuka, Marianne L, Spatz, Dietrich, Steinhuebel, Binyuan, Sun, Matthew E, Voss, Xiao, Wang, Liping, Yang, Tammie C, Yeh, Isabelle, Dussault, C Gary, Marshall, B Wesley, Trotter
Publikováno v:
Journal of medicinal chemistry. 64(21)
Identification of low-dose, low-molecular-weight, drug-like inhibitors of protein-protein interactions (PPIs) is a challenging area of research. Despite the challenges, the therapeutic potential of PPI inhibition has driven significant efforts toward
Publikováno v:
Lasers in Medical Science. 32:527-531
Hereditary hemorrhagic telangiectasia (HHT) is an inherited vascular disorder which manifests as recurrent, episodic, and potentially debilitating epistaxis. In this study, we aim to (1) characterize baseline sinonasal symptoms for HHT patients and t
Autor:
Jeffrey D. Suh, Richard L. Scawn, Aaron J. Feinstein, Todd T. Kingdom, Edward C. Kuan, Vijay R. Ramakrishnan, Henry P. Barham, Christopher F. Thompson
Publikováno v:
American Journal of Otolaryngology. 37:334-338
Background Injury to the medial rectus (MR) is a potentially devastating complication of orbital and sinus surgery. Precise knowledge of the MR relative to the lamina papyracea (LP) is important during endoscopic surgery for both Graves' ophthalmopat
Autor:
Jin Young Min, David B. Conley, Julia H. Huang, Bruce K. Tan, Robert P. Schleimer, Caroline P.E. Price, Robert C. Kern, Christopher F. Thompson, Lydia Suh, Stephanie Shintani-Smith
Publikováno v:
International Forum of Allergy & Rhinology. 6:500-507
Background Chronic rhinosinusitis (CRS) is likely a biologically heterogeneous disease process. Current guidelines propose subclassification using polyp status while others propose using mucosal eosinophilia. We hypothesized that appropriate CRS subc
Autor:
Nithin D. Adappa, James N. Palmer, Alexander G. Chiu, John M. Lee, Bradford A. Woodworth, Vijay R. Ramakrishnan, Christopher F. Thompson, Jivianne T. Lee, Jayakar V. Nayak, Jeffrey D. Suh
Publikováno v:
The Laryngoscope. 125:544-548
Objectives/hypothesis Surgical treatment of inverted papilloma (IP) of the sphenoid sinus is complicated by close proximity to vital structures of the skull base. Identifying the site of tumor attachment and achieving complete removal can be challeng
Autor:
Brendan R. D'Souza, James W. Fairman, Ben Fulroth, Michael H Serrano-Wu, Virendar K. Kaushik, Todd R. Golub, Brian K. Hubbard, Guo Wei, Chao Fang, Patrick McCarren, Clementine Feau, Christopher F. Thompson, Yikai Wang, Alison Leed, Matthew C. Clifton, Lili Wang, Michelle Palmer
Publikováno v:
ACS Medicinal Chemistry Letters. 5:1308-1312
A direct binding screen of 100 000 sp(3)-rich molecules identified a single diastereomer of a macrolactam core that binds specifically to myeloid cell leukemia 1 (MCL1). A comprehensive toolbox of biophysical methods was applied to validate the origi
Publikováno v:
International Forum of Allergy & Rhinology. 3:848-854
Background Total intravenous anesthesia (TIVA) has been shown in some studies to impact visual field, blood loss, and cardiovascular parameters during endoscopic sinus surgery when compared to inhalational anesthesia (IA). These variables are critica
Publikováno v:
American Journal of Rhinology & Allergy. 27:144-147
Background Recalcitrant sphenoid sinusitis occurs in 27% of patients undergoing revision functional endoscopic sinus surgery. One of the main causes of disease recurrence in the sphenoid is cicatricial scarring of the ostium. Highly inflammatory lesi
Autor:
Marilene B. Wang, Chi Lai, Brandon J. Kim, Maie A. St. John, David Elashoff, Tristan Grogan, Christopher F. Thompson
Publikováno v:
International Forum of Allergy & Rhinology. 3:678-683
Background Despite the improvement in survival of pediatric patients with rhabdomyosarcoma, the outcome of patients with sinonasal rhabdomyosarcoma is poor and has not significantly changed. Since few institutions have extensive experience with sinon