Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christopher E Stoddard"'
Autor:
Di Xie, Bernardo Stutz, Feng Li, Fan Chen, Haining Lv, Matija Sestan-Pesa, Jonatas Catarino, Jianlei Gu, Hongyu Zhao, Christopher E. Stoddard, Gordon G. Carmichael, Marya Shanabrough, Hugh S. Taylor, Zhong-Wu Liu, Xiao-Bing Gao, Tamas L. Horvath, Yingqun Huang
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related peptide–expressing (AGRP-expressing) neurons play an essential role in driving feeding, while also
Externí odkaz:
https://doaj.org/article/6327ef9376aa4b878e87ef53442e9d52
Autor:
Prakhar Bansal, Erin. C Banda, Heather R. Glatt-Deeley, Christopher E. Stoddard, Darcy T. Ahern, Yuvabharath Kondaveeti, Michael Nicouleau, Stefan F. Pinter
/SUMMARYExcess gene dosage from human chromosome 21 (HSA21), due to trisomy or translocation of HSA21 material, causes Down syndrome (DS). Trisomy 21 (T21) results in a large number of developmental and ongoing cellular phenotypes, raising the critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3691792e575afcb33eb0cb95f631cb1
https://doi.org/10.1101/2022.05.11.491519
https://doi.org/10.1101/2022.05.11.491519
Autor:
Dea Gorka, Noelle D. Germain, Clémence M Dupont-Thibert, Stormy J. Chamberlain, Michael S Chung, Christopher E Stoddard, Marc Lalande, Leann Crandall, Heather Glatt-Deeley, Justin Cotney, Maéva Langouët, Clarisse Orniacki
Publikováno v:
Hum Mol Genet
Prader-Willi syndrome (PWS) is characterized by neonatal hypotonia, developmental delay, and hyperphagia/obesity. This disorder is caused by the absence of paternally-expressed gene products from chromosome 15q11-q13. We previously demonstrated that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e090dcc69a9af64abdc62919e92d22d8
https://doi.org/10.1093/hmg/ddaa210
https://doi.org/10.1093/hmg/ddaa210
Autor:
Maéva Langouët, Michael S. Chung, Christopher E Stoddard, Erin Banda, Marc Lalande, Leann Crandall, Heather Glatt-Deeley, Elodie Mathieux, Clémence M Dupont-Thibert
Publikováno v:
Human Molecular Genetics. 27:505-515
Prader-Willi syndrome (PWS) is characterized by neonatal hypotonia, developmental delay and hyperphagia/obesity and is caused by the absence of paternal contribution to chromosome 15q11-q13. Using induced pluripotent stem cell (iPSC) models of PWS, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935c17f797a7001137ae1cd30b1814ac
https://doi.org/10.1093/hmg/ddx420
https://doi.org/10.1093/hmg/ddx420
Autor:
Heather R. Manring, Yongming Ren, Nikolaos Papoutsidakis, Stephen Hall, Christopher E Stoddard, Tyler L. Stevens, Stuart G. Campbell, Paul M.L. Janssen, Taylor Albertelli, Muhammad Riaz, Daniel Jacoby, Ying-Chun Lo, Claudia See, T. Jared Bunch, Xia Li, Prameela Jyothi Bobbili, Jin-Kyu Park, Nicole Tsai, Ronald Ng, Yibing Qyang, Nathan T. Wright, Maegen A. Ackermann
Publikováno v:
JCI Insight. 4
Arrhythmogenic cardiomyopathy (ACM) is an inherited disorder with variable genetic etiologies. Here, we focused on understanding the precise molecular pathology of a single clinical variant in DSP, the gene encoding desmoplakin. We initially identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac896f0056d28317cbc52731dd07768
https://doi.org/10.1172/jci.insight.128643
https://doi.org/10.1172/jci.insight.128643
Autor:
Friedrich Paulsen, Sandy Becker, Lars Bräuer, Laura Grabel, Nickesha C. Anderson, Christopher Y. Chen, Martin Schicht, Christopher E Stoddard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0198703 (2018)
PLoS ONE, Vol 13, Iss 11, p e0198703 (2018)
The transcription factorNKX2.1, expressed at high levels in the medial ganglionic eminence (MGE), is a master regulator of cortical interneuron progenitor development. To identify gene candidates with expression profiles similar toNKX2.1, previous tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1cab9545a651ed445761f686c7ca2c
https://doi.org/10.1101/330621
https://doi.org/10.1101/330621
Autor:
Thomas M. Nosek, Christopher E Stoddard, Jinhua Shen, Héctor H. Valdivia, Wen Mei Yu, Cheng-Kui Qu, Caiying Guo, Joseph A. Scherman, Marco Brotto
Publikováno v:
Nature Cell Biology. 11:769-776
The intracellular Ca(2+) concentration ([Ca(2+)](i)) in skeletal muscles must be rapidly regulated during the excitation-contraction-relaxation process. However, the signalling components involved in such rapid Ca(2+) movement are not fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ce5c19352b3478e517ec79192559b4
https://doi.org/10.1038/ncb1884
https://doi.org/10.1038/ncb1884
Autor:
Christopher E Stoddard, Cheng-Kui Qu, Wen‐Mei Yu, Caiying Guo, Marco Brotto, Thomas M. Nosek, Jinjua Shen
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cddd980f5b4fc77e9e4405f95711fc5
https://doi.org/10.1096/fasebj.23.1_supplement.780.1
https://doi.org/10.1096/fasebj.23.1_supplement.780.1