Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christopher E P, Goldring"'
Autor:
Jane I. Grove, Camilla Stephens, M. Isabel Lucena, Raúl J. Andrade, Sabine Weber, Alexander Gerbes, Einar S. Bjornsson, Guido Stirnimann, Ann K. Daly, Matthias Hackl, Kseniya Khamina-Kotisch, Jose J. G. Marin, Maria J. Monte, Sara A. Paciga, Melanie Lingaya, Shiva S. Forootan, Christopher E. P. Goldring, Oliver Poetz, Rudolf Lombaard, Alexandra Stege, Helgi K. Bjorrnsson, Mercedes Robles-Diaz, Dingzhou Li, Thi Dong Binh Tran, Shashi K. Ramaiah, Sophia L. Samodelov, Gerd A. Kullak-Ublick, Guruprasad P. Aithal, on behalf of the TransBioLine consortium
Publikováno v:
Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-15 (2023)
Abstract A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative’s TransBioLine consor
Externí odkaz:
https://doaj.org/article/01c9031ea63844faa64609c76d355eda
Autor:
Anil Kumar Mondru, Mohammad A. Aljasir, Ahmed Alrumayh, Gopika N. Nithianandarajah, Katie Ahmed, Jurgen Muller, Christopher E. P. Goldring, Bettina Wilm, Michael J. Cross
Publikováno v:
Cells, Vol 12, Iss 6, p 967 (2023)
Extracellular-signal-regulated kinase 5 (ERK5) is critical for normal cardiovascular development. Previous studies have defined a canonical pathway for ERK5 activation, showing that ligand stimulation leads to MEK5 activation resulting in dual phosph
Externí odkaz:
https://doaj.org/article/d42aa078c7ac412bb01f0a6b5a7fc15b
Autor:
Andrew V, Stachulski, Thomas A, Baillie, B Kevin, Park, R Scott, Obach, Deepak K, Dalvie, Dominic P, Williams, Abhishek, Srivastava, Sophie L, Regan, Daniel J, Antoine, Christopher E P, Goldring, Alvin J L, Chia, Neil R, Kitteringham, Laura E, Randle, Hayley, Callan, J Luis, Castrejon, John, Farrell, Dean J, Naisbitt, Martin S, Lennard
Publikováno v:
Medicinal research reviews. 33(5)
The decline in approval of new drugs during the past decade has led to a close analysis of the drug discovery process. One of the main reasons for attrition is preclinical toxicity, frequently attributed to the generation of protein-reactive drug met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d88108b8bcf52152a08943373b43a994
https://pubmed.ncbi.nlm.nih.gov/23090860
https://pubmed.ncbi.nlm.nih.gov/23090860
Publikováno v:
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 32(5)
To compare the antioxidant activity amongst the extract of Ginkgo biloba (EGb) and its main components, flavonoids and terpenoids.The induction of EGb, flavonoids and terpenoids on a typical antioxidant enzyme, glutamate cysteine ligase catalytic sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::001916f533382c1a25093ced46be0990
https://pubmed.ncbi.nlm.nih.gov/19771849
https://pubmed.ncbi.nlm.nih.gov/19771849
Autor:
Cliff Rowe, Christopher E. P. Goldring, Neil R. Kitteringham, Rosalind E. Jenkins, Brian S. Lane, Christopher Sanderson, Victoria Elliott, Vivien Platt, Peter Metcalfe, B. Kevin Park
Publikováno v:
Journal of Proteome Research; May2010, Vol. 9 Issue 5, p2658-2668, 11p