Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Christopher E Ellison"'
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010268 (2022)
R-loops are three-stranded nucleotide structures consisting of a DNA:RNA hybrid and a displaced ssDNA non-template strand. Previous work suggests that R-loop formation is primarily determined by the thermodynamics of DNA:RNA binding, which are govern
Externí odkaz:
https://doaj.org/article/187094dd0a304f41893b95ea3c716656
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009229 (2020)
Topologically associating domains, or TADs, are functional units that organize chromosomes into 3D structures of interacting chromatin. TADs play an important role in regulating gene expression by constraining enhancer-promoter contacts and there is
Externí odkaz:
https://doaj.org/article/7744f5f32f324fbbb3d49a28fd935424
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000689 (2020)
Coevolution between transposable elements (TEs) and their hosts can be antagonistic, where TEs evolve to avoid silencing and the host responds by reestablishing TE suppression, or mutualistic, where TEs are co-opted to benefit their host. The TART-A
Externí odkaz:
https://doaj.org/article/ee5cf49cb66647c29b3621b92ae65864
Autor:
Christopher E Ellison, Doris Bachtrog
Publikováno v:
eLife, Vol 4 (2015)
Transposable elements (TEs) allow rewiring of regulatory networks, and the recent amplification of the ISX element dispersed 77 functional but suboptimal binding sites for the dosage compensation complex to a newly formed X chromosome in Drosophila.
Externí odkaz:
https://doaj.org/article/77a01e211c1548ecb1a6c3daf038dd8d
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96784 (2014)
Strain selection and strain improvement are the first, and arguably most important, steps in the industrial production of biological compounds by microorganisms. While traditional methods of mutagenesis and selection have been effective in improving
Externí odkaz:
https://doaj.org/article/e3ed4f3f67f840f39e6e7dc0494b7194
Autor:
Qi Zhou, Christopher E Ellison, Vera B Kaiser, Artyom A Alekseyenko, Andrey A Gorchakov, Doris Bachtrog
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001711 (2013)
Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertran
Externí odkaz:
https://doaj.org/article/f03c7fb20ca248e3b5c3da55b3d92c6e
Autor:
Wilson Leung, Nicole Torosin, Weihuan Cao, Laura K Reed, Cindy Arrigo, C R Sarah Elgin, Christopher E Ellison
Publikováno v:
bioRxiv
Flow cytometry estimates of genome sizes among species ofDrosophilashow a 3-fold variation, ranging from ∼127 Mb inDrosophila mercatorumto ∼400 Mb inDrosophila cyrtoloma. However, the assembled portion of the Muller F Element (orthologous to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f646c3f07f4c38968429d55efb069b9
https://doi.org/10.1101/2023.05.22.541758
https://doi.org/10.1101/2023.05.22.541758
Transposable elements (TEs) are selfish DNA sequences that can replicate themselves in their host's genome. Hosts have evolved specialized strategies for mitigating the deleterious consequences of TE activity. In Drosophila, the piRNA pathway is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ba7750cf3ddea8ef4d8d710dd99317
https://doi.org/10.31219/osf.io/btvmh
https://doi.org/10.31219/osf.io/btvmh
Publikováno v:
Molecular Biology and Evolution. 39
Topologically associating domains (TADs) are thought to play an important role in preventing gene misexpression by spatially constraining enhancer–promoter contacts. The deleterious nature of gene misexpression implies that TADs should, therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572f3a61d13a9b303437a5b33466bba1
https://doi.org/10.1093/molbev/msac216
https://doi.org/10.1093/molbev/msac216
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Transposable elements (TEs) must replicate in germline cells to pass novel insertions to offspring. In Drosophila melanogaster ovaries, TEs can exploit specific developmental windows of opportunity to evade host silencing and increase their copy numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b507dbbe3d6accc83bbc50be2fc7ae6a
http://europepmc.org/articles/PMC8617248
http://europepmc.org/articles/PMC8617248