Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christopher Donley"'
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S3 - PDF file 26K, Figure S3. AD-01 is not cytotoxic. No change in surviving fraction following AD-01 treatment in both MDA-231 and MCF-7 cells was observed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fe4f9b732dcda850b879c981eeb059
https://doi.org/10.1158/1078-0432.22448499
https://doi.org/10.1158/1078-0432.22448499
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Table S2 - PDF file 86K, A: Clinical information and the average MFE for every solid primary breast tumour received; tumours of similar grade and status were combined and the average MFE calculated. B: Tumour initiation data following implantation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d00fc63e247f25aa6b096ab5087f046
https://doi.org/10.1158/1078-0432.22448478
https://doi.org/10.1158/1078-0432.22448478
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S6 - PDF file 42K, Figure S6. High FKBPL and low Sox2 expression shows a trend towards better patient survival. Samples with opposing FKBPL and Sox2 expression (high FKBPL/low Sox2 and low FKBPL/high Sox2) were analyzed using microarray data f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032f5507a342ba5455aed88f17a70713
https://doi.org/10.1158/1078-0432.22448490
https://doi.org/10.1158/1078-0432.22448490
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S4 - PDF file 73K, Figure S4. (A) Protein levels of Nanog and Oct4 in MDA-231 cells following treatment with HA or AD-01, alone or in combination. (B) Protein levels of Nanog and Oct4 in MDA-231 cells following transfection with FKBPL siRNA (s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8802602ba67909c5d85594d3892136
https://doi.org/10.1158/1078-0432.22448496.v1
https://doi.org/10.1158/1078-0432.22448496.v1
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S1 - PDF file 49K, Figure S1. (A) Mammosphere formation efficiency (MFE) in MDA-231 cells exposed to varying concentrations of AD-01. (B) Primary (1), secondary (2) and tertiary (3) mammosphere formation in the MDA-231 cell line following 1 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584f2b5e42f7b680008d26e5acb39c83
https://doi.org/10.1158/1078-0432.22448505
https://doi.org/10.1158/1078-0432.22448505
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Supplementary Data Legends - PDF file 63K, Data legends for supplemental figs S1 to S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00517633530e5eda6270f76f4a0a4907
https://doi.org/10.1158/1078-0432.22448484
https://doi.org/10.1158/1078-0432.22448484
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Table S1 - PDF file 66K, Percentage ESA+/CD44+/CD24- or ALDH+ cells gated using flow cytometry (n=3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1806f0e1cebb70635e5bc30fb380e4ff
https://doi.org/10.1158/1078-0432.22448481.v1
https://doi.org/10.1158/1078-0432.22448481.v1
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S7 - PDF file 47K, Figure S7. High FKBPL and low Oct4 expression shows a trend towards better patient survival. Samples with opposing FKBPL and Oct4 expression (high FKBPL/low Oct4 and low FKBPL/high Oct4) were analyzed using microarray data f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e81d983569f2647a9062bfc2a388c0
https://doi.org/10.1158/1078-0432.22448487.v1
https://doi.org/10.1158/1078-0432.22448487.v1
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Purpose: FK506-binding protein like (FKBPL) and its peptide derivative, AD-01, have already shown tumor growth inhibition and CD44-dependent antiangiogenic activity. Here, we explore the ability of AD-01 to target CD44-positive breast cancer stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c26b2c05a077ca828a5f0398ae81aa
https://doi.org/10.1158/1078-0432.c.6521412.v1
https://doi.org/10.1158/1078-0432.c.6521412.v1
Autor:
Tracy Robson, Robert B. Clarke, Eric O'Neill, Helen O. McCarthy, Stuart McIntosh, Adrien Kissenpfennig, Christopher Donley, Rachel Bennett, Hayley D. McKeen, Puthen V. Jithesh, Matthew P. Ablett, Hannah Harrison, Angelos Papaspyropoulos, Anita Yakkundi, Lana McClements
Figure S5 - PDF file 48K, Figure S5. High FKBPL and low Nanog expression correlates with better DMFS and shows a trend towards better RFS. Samples with opposing FKBPL and Nanog expression (high FKBPL/low Nanog and low FKBPL/high Nanog) were analysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6afc9471422b0ccabfb345bc55f80b
https://doi.org/10.1158/1078-0432.22448493
https://doi.org/10.1158/1078-0432.22448493