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pro vyhledávání: '"Christopher Daniel Morrone"'
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-34 (2023)
Abstract Failed proteostasis is a well-documented feature of Alzheimer’s disease, particularly, reduced protein degradation and clearance. However, the contribution of failed proteostasis to neuronal circuit dysfunction is an emerging concept in ne
Externí odkaz:
https://doaj.org/article/372b7ce03b5e43bca8135d87b1fee51f
Autor:
Christopher Daniel Morrone, Aaron Yenhsin Lai, Jossana Bishay, Mary Elizabeth Hill, JoAnne McLaurin
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-22 (2022)
Abstract Background Patient-to-patient variability in the degree to which β-amyloid, tau and neurodegeneration impact cognitive decline in Alzheimer’s disease (AD) complicates disease modeling and treatment. However, the underlying mechanisms lead
Externí odkaz:
https://doaj.org/article/31c9b4e8d4294f769bec737ace21dcaf
Autor:
Christopher Daniel Morrone, Arielle A. Tsang, Sarah M. Giorshev, Emily E. Craig, Wai Haung Yu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2023)
Electrophysiological and behavioral alterations, including sleep and cognitive impairments, are critical components of age-related decline and neurodegenerative diseases. In preclinical investigation, many refined techniques are employed to probe the
Externí odkaz:
https://doaj.org/article/f100147d660541d180f6b567bf5c7954