Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christopher D.V. Black"'
Autor:
Christopher D.V. Black, Ronnie T.P. Poon, Bradford J. Wood, Steven K. Libutti, G. Seidel, Raj Prabhakar, Michelle Eugeni, Julia K. Locklin, Kelvin K. Ng, Michael Kolf, Matthew R. Dreher, Ziv Neeman, Sergio Dromi
Publikováno v:
Journal of vascular and interventional radiology : JVIR. 23(2)
Purpose: A phase I dose escalation study was performed with systemically delivered lyso-thermosensitive liposomal doxorubicin (LTLD). The primary objectives were to determine the safe maximum tolerated dose (MTD), pharmacokinetic properties, and dose
Autor:
Gurupadappa V. Betageri, Christopher D.V. Black, Janos Szebeni, Larry M. Wahl, John N. Weinstein
Publikováno v:
Journal of Pharmacy and Pharmacology. 45:48-53
Liposomes bearing surface-attached antibody (L-Ab) molecules can be used for various purposes including the immunospecific delivery of drugs or other materials to antigenic target cells. In this study, L-Ab were prepared to deliver an anti-human immu
Autor:
Jack A. Roth, W. Matthews, James B. Mitchell, Angelo Russo, Helen W. Pogrebniak, Harvey I. Pass, Christopher D.V. Black, Paul D. Smith
Publikováno v:
Surgical Oncology. 2:31-42
Photodynamic therapy (PDT) was performed in vitro and in vivo using monoclonal antibody conjugated to hematoporphyrin (HP). The antibody (45-2D9) recognized a cell surface glycoprotein on cells derived from NIH 3T3 cells which were transformed with t
Autor:
C. Murali Krishna, Amram Samuni, Harry L. Malech, Christopher D.V. Black, Angelo Russo, Dwight Kaufman, John A. Cook
Publikováno v:
Archives of biochemistry and biophysics. 286(1)
Oxygen-derived active species and superoxide radical in particular are generated and excreted upon granulocyte activation and are instrumental in host defense against bacterial and fungal infections. Associated with the activation of neutrophils is a
Publikováno v:
Free radical research communications.
Activation of neutrophils results in a one-electron reduction of oxygen to produce the superoxide anion and other oxygen-derived, microbicidal species. Evidence from many kinetic studies of oxygen-derived radicals generated by stimulated neutrophils
Publikováno v:
Free radical biologymedicine. 10(5)
The means by which neutrophils within the body ward off infectious and neoplastic processes by the activation of molecular oxygen, as well as how such mechanisms dysfunction, is the subject of extensive ongoing research. Most previous studies of neut
Autor:
Christopher D.V. Black, Sharon M. Wahl, Larry M. Wahl, Mikulas Popovic, Suzanne Gartner, Gurupadappa V. Betageri, Robert Parker, John N. Weinstein, Janos Szebeni
Publikováno v:
AIDS research and human retroviruses. 6(5)
The antiviral effects of 2',3'-dideoxycytidine (ddC), 2',3'-dideoxycytidine-5'-triphosphate (ddCTP) and liposome-encapsulated ddCTP [L(ddCTP)] were compared in cultured human monocyte-macrophages (M/M) infected with HIV-1. These treatments inhibited
Autor:
Gunter Thomas, Christopher D.V. Black, Eric F. Bernstein, Roger E. Solomon, Walter S. Friauf, Paul D. Smith, Joseph F. Fessler, John W. Cole, Angelo Russo
Publikováno v:
Archives of Dermatology. 127:1794
• Photodynamic therapy involves the use of light of appropriate wavelength to excite a photosensitizer resulting in tissue destruction. The photosensitizer dihematoporphyrin ether is selectively retained in tumors allowing for tumor destruction whi
Autor:
Susan N. Cook, Angelo Russo, Joyce M. Fisher, Eli Glatstein, James Mitchell, Eric F. Bernstein, William DeGraff, Richard C. Schlegel, Joseph Glass, Christopher D.V. Black
Publikováno v:
Archives of Dermatology. 127:683
• Photodynamic therapy involves the use of light of appropriate wavelength to excite a photosensitizer to result in tissue destruction. The photosensitizer dihematoporphyrin ether and red light were used to treat normal and human papilloma virus ty
Publikováno v:
Cellular Immunology. 111:420-432
The requirements for the induction of IL-2 receptor expression following lymphocyte stimulation in vitro are well understood but little is known about the role of IL-2 and the IL-2 receptor in lymphocyte activation in vivo . Following the subcutaneou