Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christopher D. Watt"'
Autor:
Spyridon Bakas, Chiharu Sako, Hamed Akbari, Michel Bilello, Aristeidis Sotiras, Gaurav Shukla, Jeffrey D. Rudie, Natali Flores Santamaría, Anahita Fathi Kazerooni, Sarthak Pati, Saima Rathore, Elizabeth Mamourian, Sung Min Ha, William Parker, Jimit Doshi, Ujjwal Baid, Mark Bergman, Zev A. Binder, Ragini Verma, Robert A. Lustig, Arati S. Desai, Stephen J. Bagley, Zissimos Mourelatos, Jennifer Morrissette, Christopher D. Watt, Steven Brem, Ronald L. Wolf, Elias R. Melhem, MacLean P. Nasrallah, Suyash Mohan, Donald M. O’Rourke, Christos Davatzikos
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) Magnetic Resonance Imaging Technology Type(s) Magnetic Resonance Imaging of the Brain with and without Contrast Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment brain Sample Characteristic - Location Un
Externí odkaz:
https://doaj.org/article/5d5b415e3a86419991ae9fdec07415bc
Autor:
MacLean P. Nasrallah MD, PhD, Zev A. Binder MD, PhD, Derek A. Oldridge MD, PhD, Jianhua Zhao PhD, FACMG, David B. Lieberman MS, CGC, Jacquelyn J. Roth PhD, Christopher D. Watt MD, PhD, Shrey Sukhadia MS, Eva Klinman PhD, Robert D. Daber PhD, Arati Desai MD, Steven Brem MD, Donald M. O’Rourke MD, Jennifer J. D. Morrissette PhD
Publikováno v:
Academic Pathology, Vol 6 (2019)
Molecular profiling of glioblastoma has revealed complex cytogenetic, epigenetic, and molecular abnormalities that are necessary for diagnosis, prognosis, and treatment. Our neuro-oncology group has developed a data-driven, institutional consensus gu
Externí odkaz:
https://doaj.org/article/d2e4dd6467f7414987f25784371d72bc
Autor:
Marlise R. Luskin, Auris O. Huen, Sarah A. Brooks, Campbell Stewart, Christopher D. Watt, Jennifer J.D. Morrissette, David B. Lieberman, Adam Bagg, Misha Rosenbach, Alexander E. Perl
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Externí odkaz:
https://doaj.org/article/4d7ed4df971e4f339e718854d55222a7
Autor:
Alexander E. Perl, Catherine C. Smith, Martin Carroll, Neil P. Shah, Selina M. Luger, Aaron C. Logan, Safoora Deihimi, Lisa H.F. McGary, Cheryl A.C. Peretz, RosaAnna DeFilippis, Elisabeth A. Lasater, Saurabh Asthana, Christopher D. Watt, Robert Durruthy-Durruthy, Maurizio Pellegrino, Dennis J. Eastburn, Jennifer J.D. Morrissette, Eunice S. Wang, Jonathan Canaani, Timothy Ferng, Christine M. McMahon
Gilteritinib is a potent and selective FLT3 kinase inhibitor with single-agent clinical efficacy in relapsed/refractory FLT3-mutated acute myeloid leukemia (AML). In this context, however, gilteritinib is not curative, and response duration is limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9342e80b4dcae04c4e27e5d1a7598d23
https://doi.org/10.1158/2159-8290.c.6548240.v1
https://doi.org/10.1158/2159-8290.c.6548240.v1
Autor:
Alexander E. Perl, Catherine C. Smith, Martin Carroll, Neil P. Shah, Selina M. Luger, Aaron C. Logan, Safoora Deihimi, Lisa H.F. McGary, Cheryl A.C. Peretz, RosaAnna DeFilippis, Elisabeth A. Lasater, Saurabh Asthana, Christopher D. Watt, Robert Durruthy-Durruthy, Maurizio Pellegrino, Dennis J. Eastburn, Jennifer J.D. Morrissette, Eunice S. Wang, Jonathan Canaani, Timothy Ferng, Christine M. McMahon
Supplementary Tables 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe210e27d3ccf3dea02a649dd8d167e
https://doi.org/10.1158/2159-8290.22536788
https://doi.org/10.1158/2159-8290.22536788
Autor:
Alexander E. Perl, Catherine C. Smith, Martin Carroll, Neil P. Shah, Selina M. Luger, Aaron C. Logan, Safoora Deihimi, Lisa H.F. McGary, Cheryl A.C. Peretz, RosaAnna DeFilippis, Elisabeth A. Lasater, Saurabh Asthana, Christopher D. Watt, Robert Durruthy-Durruthy, Maurizio Pellegrino, Dennis J. Eastburn, Jennifer J.D. Morrissette, Eunice S. Wang, Jonathan Canaani, Timothy Ferng, Christine M. McMahon
Supplementary Figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7cefe956e48cc0c0783cbdb797c9d6
https://doi.org/10.1158/2159-8290.22536791.v1
https://doi.org/10.1158/2159-8290.22536791.v1
Autor:
Matthew C Hiemenz, Stephan Kadauke, David B Lieberman, David B Roth, Jianhua Zhao, Christopher D Watt, Robert D Daber, Jennifer J D Morrissette
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152851 (2016)
Next-generation sequencing (NGS) is a powerful platform for identifying cancer mutations. Routine clinical adoption of NGS requires optimized quality control metrics to ensure accurate results. To assess the robustness of our clinical NGS pipeline, w
Externí odkaz:
https://doaj.org/article/443905187da04c1b9c5ac483ee231ef6
Autor:
Alexander E. Perl, Martin Carroll, Bryan Rea, Jonathan Canaani, Christopher D. Watt, Jennifer J.D. Morrissette, Julianne Qualtieri, Rachel L. Sargent, Christine M. McMahon
Publikováno v:
Blood Advances. 3:1581-1585
Key Points Gilteritinib induces 2 distinct marrow responses in FLT3-mutated AML: responses with and without differentiation. Ongoing clonal hematopoiesis is ubiquitous during gilteritinib therapy and may promote genetic evolution and drug resistance.
Autor:
Xiaobin Liu, Reza Nejati, Stephen J. Schuster, Honore T. Strauser, Mariusz A. Wasik, Selene Nunez-Cruz, Carl H. June, Hong Y. Wang, Qian Zhang, Paul J. Zhang, Agata M. Bogusz, J. Joseph Melenhorst, Christopher D. Watt, Simon F. Lacey, Sarah Brooks, Elena Orlando
Publikováno v:
Blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b798d3c9dafd189c9fb3d3261997731
https://europepmc.org/articles/PMC7582558/
https://europepmc.org/articles/PMC7582558/
Autor:
Christos Davatzikos, Sung Min Ha, Donald M. O'Rourke, MacLean Nasrallah, Hamed Akbari, Chiharu Sako, Zev A. Binder, Elizabeth Mamourian, Saima Rathore, Stephen J Bagley, Christopher D. Watt, Gaurav Shukla
Publikováno v:
Neuro Oncol
BACKGROUND High expression of O6-methylguanine-DNA methyltransferase (MGMT) in glioblastoma is associated with resistance to temozolomide, as tumor cells lacking MGMT activity are significantly more sensitive to the cytotoxic effects of temozolomide.