Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Christopher D. Warren"'
Autor:
Hargittai, Balazs
Publikováno v:
Structural Chemistry; August 2000, Vol. 11 Issue: 4 p271-273, 3p
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Chromatin is the complex assembly of nucleic acids and proteins that makes up the physiological form of the eukaryotic genome. The nucleosome is the fundamental repeating unit of chromatin, and is composed of ∼147 bp of DNA wrapped around a histone
Autor:
Jerome M. Karp, Sean M. Cahill, Michael Brenowitz, Takashi Onikubo, Christopher D. Warren, David Shechter, Mark E. Girvin, David Cowburn, Tsutomu Matsui
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Nature Communications
Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the maternal storage and zygotic release of histones H2A/H2B. Npm contains a pentameric N-terminal core domain and an intrinsically disordered C-terminal tail domain. Though
Autor:
David Shechter, Christopher D. Warren
Publikováno v:
Journal of Molecular Biology. 429:2401-2426
Chromatin is the complex of eukaryotic DNA and proteins required for the efficient compaction of the nearly two-meter long human genome into a roughly ten-micron diameter cell nucleus. The fundamental repeating unit of chromatin is the nucleosome: 14
Autor:
Michael Brenowitz, Huiyong Cheng, Sergei Khrapunov, Christopher D. Warren, John M. Greally, Esther R. Berko
Publikováno v:
Biochemistry
The protein MeCP2 mediates epigenetic regulation by binding methyl-CpG (mCpG) sites on chromatin. MeCP2 consists of six domains of which one, the methyl binding domain (MBD), binds mCpG sites in duplex DNA. We show that solution conditions with physi
Autor:
Joseph Alroy, Christopher D. Warren
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 12:483-496
Lysosomal storage diseases are a group of inherited and acquired disorders with different clinical manifestations, affecting mammals 30,43,49,97 and birds. 16,36,53,59 Depending on the mutation site and/or defective gene, they may be presented as an
Autor:
Guillermo M. Ruiz-Palacios, Prasoon Chaturvedi, Larry K. Pickering, David S. Newburg, Christopher D. Warren
Publikováno v:
Analytical Biochemistry. 251:89-97
Human milk is rich in oligosaccharides, some of which inhibit toxins and pathogens involved in diseases of infants. To investigate qualitative and quantitative individual variation of human milk oligosaccharides, a sensitive method for routine identi
Publikováno v:
Glycobiology. 4:551-566
Previously, alpha-mannosidases were classified as enzymes that process newly formed N-glycans or degrade mature glycoproteins. In this review, we suggest that two endoplasmic reticulum (ER) alpha-mannosidases, previously assigned processing roles, ha
Publikováno v:
Scopus-Elsevier
Biosynthetic intermediates for the mammalian glycosylphosphatidylinositol (GPI) anchor have been described. The earliest GPI anchor precursor is N-acetylglucosaminylphosphatidylinositol, which is deacetylated to give glucosaminylphosphatidylinositol.
Publikováno v:
Archives of Biochemistry and Biophysics. 298:49-55
In this work we examine the carbohydrate binding properties of human placental mannose receptor (HMR) using a rapid and sensitive enzyme-linked immunosorbent microplate assay. The assay is based on the inhibition of binding of highly purified recepto