Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christopher D. Vulpe"'
Autor:
Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn, Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins, Craig A. McFarland
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract Background The health and resilience of species in natural environments is increasingly challenged by complex anthropogenic stressor combinations including climate change, habitat encroachment, and chemical contamination. To better understan
Externí odkaz:
https://doaj.org/article/1f4c79ccc7f04001ab58b3341aa2e22c
Autor:
Prashant Sharma, Marie Reichert, Yan Lu, Thomas C Markello, David R Adams, Peter J Steinbach, Brie K Fuqua, Xenia Parisi, Stephen G Kaler, Christopher D Vulpe, Gregory J Anderson, William A Gahl, May Christine V Malicdan
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008143 (2019)
Maintenance of the correct redox status of iron is functionally important for critical biological processes. Multicopper ferroxidases play an important role in oxidizing ferrous iron, released from the cells, into ferric iron, which is subsequently d
Externí odkaz:
https://doaj.org/article/8434e917264b45e197052e868151132b
Autor:
Sheridan L. Helman, Jie Zhou, Brie K. Fuqua, Yan Lu, James F. Collins, Huijun Chen, Christopher D. Vulpe, Gregory J. Anderson, David M. Frazer
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, vol 36, iss 2
Biometals
Biometals
The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH) and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron homeostasis. Each of these enzymes contains six biosynthetically incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b61329225401e190bc038d5c2214ce
https://escholarship.org/uc/item/35n736xd
https://escholarship.org/uc/item/35n736xd
Autor:
Christoph Driessen, Herman S. Overkleeft, Christopher D. Vulpe, Hesso Farhan, Marc Pilon, Celia R. Berkers, Bart Everts, Alex Loguinov, J. Thomas Hannich, Heinz Ludwig, Arnold Bolomsky, Julia Huber, Marcus Ståhlman, Jan Borén, Bogdan I. Florea, Marc Sathianathan, Lorina Büchler, Santosh Phuyal, Mario Ruiz, Alwin J. van der Ham, Esther A. Zaal, Amin Sobh, Sara C. Stolze, Andrej Besse, Lenka Besse
Cells pre-treated for 3h with 10 µM brefeldin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33552871e6e1733063c907c47c924f2a
https://doi.org/10.1158/0008-5472.22429021
https://doi.org/10.1158/0008-5472.22429021
Autor:
Christoph Driessen, Herman S. Overkleeft, Christopher D. Vulpe, Hesso Farhan, Marc Pilon, Celia R. Berkers, Bart Everts, Alex Loguinov, J. Thomas Hannich, Heinz Ludwig, Arnold Bolomsky, Julia Huber, Marcus Ståhlman, Jan Borén, Bogdan I. Florea, Marc Sathianathan, Lorina Büchler, Santosh Phuyal, Mario Ruiz, Alwin J. van der Ham, Esther A. Zaal, Amin Sobh, Sara C. Stolze, Andrej Besse, Lenka Besse
Supplementary Methods, figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182275f89436b405bcad2fd645409448
https://doi.org/10.1158/0008-5472.22429033
https://doi.org/10.1158/0008-5472.22429033
Autor:
Christoph Driessen, Herman S. Overkleeft, Christopher D. Vulpe, Hesso Farhan, Marc Pilon, Celia R. Berkers, Bart Everts, Alex Loguinov, J. Thomas Hannich, Heinz Ludwig, Arnold Bolomsky, Julia Huber, Marcus Ståhlman, Jan Borén, Bogdan I. Florea, Marc Sathianathan, Lorina Büchler, Santosh Phuyal, Mario Ruiz, Alwin J. van der Ham, Esther A. Zaal, Amin Sobh, Sara C. Stolze, Andrej Besse, Lenka Besse
The HIV-protease inhibitor nelfinavir has shown broad anticancer activity in various preclinical and clinical contexts. In patients with advanced, proteasome inhibitor (PI)–refractory multiple myeloma, nelfinavir-based therapy resulted in 65% parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e901416a1a64be63e31f0e7aa9f10287
https://doi.org/10.1158/0008-5472.c.6513214.v1
https://doi.org/10.1158/0008-5472.c.6513214.v1
Publikováno v:
Reference Module in Biomedical Sciences ISBN: 9780128012383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87062b24974724d8e33c189aee8692d6
https://doi.org/10.1016/b978-0-12-824315-2.00605-9
https://doi.org/10.1016/b978-0-12-824315-2.00605-9
Autor:
Nam H. K. Nguyen, Roya Rafiee, Abderrahmane Tagmount, Amin Sobh, Alex Loguinov, Angelica K. de Jesus Sosa, Abdelrahman H. Elsayed, Mohammed Gbadamosi, Nathan Seligson, Christopher R. Cogle, Jeffery Rubnitz, Raul Ribeiro, James Downing, Xueyuan Cao, Stanley B. Pounds, Christopher D. Vulpe, Jatinder K. Lamba
Publikováno v:
Blood advances.
Etoposide is used to treat a wide range of malignant cancers, including acute myeloid leukemia (AML) in children. Despite the use of intensive chemotherapeutic regimens containing etoposide, a significant proportion of pediatric patients with AML bec
Autor:
Dinesh, Thummuri, Sajid, Khan, Patrick W, Underwood, Peiyi, Zhang, Janet, Wiegand, Xuan, Zhang, Vivekananda, Budamagunta, Amin, Sobh, Abderrahmane, Tagmount, Alexander, Loguinov, Andrea N, Riner, Ashwin S, Akki, Elizabeth, Williamson, Robert, Hromas, Christopher D, Vulpe, Guangrong, Zheng, Jose G, Trevino, Daohong, Zhou
Publikováno v:
Mol Cancer Ther
Pancreatic cancer is the third most common cause of cancer-related deaths in the USA. While gemcitabine (GEM) is the standard-of-care for most pancreatic cancer patients, its efficacy is limited by the development of resistance. This resistance may b
Autor:
Huacheng, Luo, Amin, Sobh, Christopher D, Vulpe, Edmond, Brewer, Sinisa, Dovat, Yi, Qiu, Suming, Huang
Publikováno v:
J Vis Exp
CCCTC-binding factor (CTCF)-mediated stable topologically associating domains (TADs) play a critical role in constraining interactions of DNA elements that are located in neighboring TADs. CTCF plays an important role in regulating the spatial and te