Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher D. Thouvenel"'
Autor:
David J Rawlings, Christopher D Thouvenel, Baidong Hou, Fahd Al Qureshah, Sara Sagadiev, Shuozhi Liu, Zhaolin Hua, Mridu Acharya, Richard G James
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/de217af1026245a0b5f8742c327f3886
Autor:
David J Rawlings, Quan-Zhen Li, Christopher D Thouvenel, Tanvi Arkatkar, Shaun W Jackson, Kristy Chiang, Andrea D Largent, Samuel W Du, Natali Shumlak, Jonathan Woods
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6a9a8b697a3d4245b0c391ad3de077fd
Autor:
Samuel W. Du, Andrea D Largent, Quan Zhen Li, Kristy Chiang, Shaun W. Jackson, David J. Rawlings, Baidong Hou, Yifan Liu, Christopher D. Thouvenel, Tanvi Arkatkar, Natali Shumlak, Jonathan Woods
Publikováno v:
The Journal of Immunology. 207:2217-2222
Cognate interactions between autoreactive B and T cells promote systemic lupus erythematosus pathogenesis by inter alia facilitating spontaneous germinal center (GC) formation. Whereas both myeloid and B cell APCs express B7 ligands (CD80 and CD86),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef3488a7e9fc129a245f9fde16b23a9f
https://doi.org/10.4049/jimmunol.2100548
https://doi.org/10.4049/jimmunol.2100548
Autor:
Malika Hale, Jason Netland, Yu Chen, Christopher D. Thouvenel, Katherine Nabel Smith, Lucille M. Rich, Elizabeth R. Vanderwall, Marcos C. Miranda, Julie Eggenberger, Linhui Hao, Michael J. Watson, Charles C. Mundorff, Lauren B. Rodda, Neil P. King, Miklos Guttman, Michael Gale, Jonathan Abraham, Jason S. Debley, Marion Pepper, David J. Rawlings
Publikováno v:
Journal of Experimental Medicine. 219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa4ec6b71eae04027dd17c9bad6c227f
https://doi.org/10.1084/jem.2022084908172022c
https://doi.org/10.1084/jem.2022084908172022c
Autor:
Malika Hale, Jason Netland, Yu Chen, Christopher D. Thouvenel, Katherine Nabel Smith, Lucille M. Rich, Elizabeth R. Vanderwall, Marcos C. Miranda, Julie Eggenberger, Linhui Hao, Michael J. Watson, Charles C. Mundorff, Lauren B. Rodda, Neil P. King, Miklos Guttman, Michael Gale, Jonathan Abraham, Jason S. Debley, Marion Pepper, David J. Rawlings
Publikováno v:
The Journal of experimental medicine. 219(9)
Humoral immunity to SARS-CoV-2 can be supplemented with polyclonal sera from convalescent donors or an engineered monoclonal antibody (mAb) product. While pentameric IgM antibodies are responsible for much of convalescent sera’s neutralizing capaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2ad5a20085cb3b87ebd4b689c5e4a4
https://pubmed.ncbi.nlm.nih.gov/36036783
https://pubmed.ncbi.nlm.nih.gov/36036783
Autor:
Shaun W. Jackson, Samuel W. Du, Andrea D Largent, Kristy Chiang, Tanvi Arkatkar, David J. Rawlings, Baidong Hou, Christopher D. Thouvenel, Quan Zhen Li, Holly M. Jacobs, Fahd Al Qureshah
Publikováno v:
The Journal of Immunology. 203:2817-2826
Age-associated B cells (ABCs) are a unique subset of B cells defined by surface CD11b and CD11c expression. Although ABC expansion has been observed in both human and animal studies in the setting of advanced age, during humoral autoimmunity and foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7819feac388afb23b05aa2163b8e0c
https://doi.org/10.4049/jimmunol.1900404
https://doi.org/10.4049/jimmunol.1900404
Autor:
Kristy Chiang, Quan Zhen Li, David J. Rawlings, Shaun W. Jackson, Tanvi Arkatkar, Christopher D. Thouvenel, Andrea D Largent, Natali Shumlak, Samuel W. Du, Jonathan Woods
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35f9c5b8896098f6360f32a41afa598
https://doaj.org/article/6a9a8b697a3d4245b0c391ad3de077fd
https://doaj.org/article/6a9a8b697a3d4245b0c391ad3de077fd
Autor:
Shuozhi Liu, Christopher D. Thouvenel, Sara Sagadiev, Fahd Al Qureshah, Baidong Hou, Mridu Acharya, Richard G. James, Zhaolin Hua, David J. Rawlings
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c433b836df06647d08548baf02b8313
https://doi.org/10.1136/lupus-2021-lupus21century.98
https://doi.org/10.1136/lupus-2021-lupus21century.98
Autor:
Zhaolin Hua, Mridu Acharya, Christopher D. Thouvenel, Shuozhi Liu, Baidong Hou, David J. Rawlings, Sara Sagadiev, Richard G. James, Fahd Al Qureshah
Publikováno v:
Journal of Experimental Medicine. 218
While phosphatidylinositide 3-kinase delta (PI3Kδ) plays a critical role in humoral immunity, the requirement for PI3Kδ signaling in plasma cells remains poorly understood. Here, we used a conditional mouse model of activated PI3Kδ syndrome (APDS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdb8829d1b1ae153bb2dd3e21214919
https://doi.org/10.1084/jem.20211035
https://doi.org/10.1084/jem.20211035
Autor:
Christopher D. Thouvenel, Silvia Portugal, Eric M. Lynch, Mary F. Fontana, Marie Pancera, Suruchi Singh, Jason Netland, Kennidy K Takehara, Marion Pepper, Neil P. King, Peter D. Crompton, Gladys J. Keitany, Yu Chen, Carole A. Long, Akshay T. Krishnamurty, Kazutoyo Miura, David J. Rawlings, Marcos C. Miranda, Justin M. Kollman
Publikováno v:
The Journal of Experimental Medicine
Thouvenel et al. isolate BCR sequences from Plasmodium-specific IgM+ human memory B cells, expressing them as both IgM and IgG molecules. Multimerization confers superior antigen binding and parasite restriction, highlighting an important role for me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05081f2f23d9d75c33be1816f0e6e347
https://doi.org/10.1084/jem.20200942
https://doi.org/10.1084/jem.20200942