Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Christopher D. Payne"'
Autor:
Clara J. M. Hoppe, Christel S. Hassler, Christopher D. Payne, Philippe D. Tortell, Björn Rost, Scarlett Trimborn
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/9a093b3734184027be5fbad2e0521a25
Autor:
Wen Xu, Galen H. Shi, Jonathan G Parker, Michael R. De Felippis, David S. Collins, Vincent Corvari, Christopher D. Payne, Karthik Pisupati
Publikováno v:
Pharmaceutical Research. 38:779-793
The objective of this work was to systematically evaluate the effects of formulation composition on subcutaneous injection site pain (ISP) using matrices comprising of common pharmaceutical excipients. Two randomized, blinded, crossover studies in he
Publikováno v:
Clinical Pharmacology in Drug Development. 9:952-960
The objective of this phase 1 study was to evaluate the pharmacokinetics, safety, and tolerability of baricitinib after single and multiple doses in healthy Chinese adults. Eligible subjects received a once-daily dose of baricitinib 2, 4, or 10 mg or
Autor:
Sanjay Chabra, B. J. Gill, Gaia Gallo, Danting Zhu, Celine Pitou, Christopher D. Payne, Ana Accioly, Luis Puig
Publikováno v:
ADVANCES IN THERAPY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Introduction Subcutaneous (SC) injection is a common route of drug administration; however, injection site pain (ISP) might create a negative patient experience. We evaluated ISP, bioequivalence, and overall safety of the citrate-free (CF) formulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7330e2716abf3817463efd15fe21496
https://ddd.uab.cat/record/277645
https://ddd.uab.cat/record/277645
Autor:
Kenneth C. Cassidy, Christopher D. Payne, Scott M. Hynes, Enaksha R Wickremsinhe, Yingying Guo
Publikováno v:
Xenobiotica. 50:793-804
The disposition and metabolism of prexasertib, a CHK-1 inhibitor was characterised over a 120 h period following a single 170-mg intravenous dose of [14C]prexasertib (50 µCi) to 6 patients with adv...
Autor:
Galen H, Shi, Karthik, Pisupati, Jonathan G, Parker, Vincent J, Corvari, Christopher D, Payne, Wen, Xu, David S, Collins, Michael R, De Felippis
Publikováno v:
Pharmaceutical research. 38(5)
The objective of this work was to systematically evaluate the effects of formulation composition on subcutaneous injection site pain (ISP) using matrices comprising of common pharmaceutical excipients.Two randomized, blinded, crossover studies in hea
Autor:
Sólveig Rósa Ólafsdóttir, Hans-Uwe Dahms, Marie Küter, Sonia Blanco-Ameijeiras, Marius N. Müller, Susan E. Hartman, Dana Greeley, Liisa M. Jantunen, Joana Barcelos e Ramos, Olivier Gilg, Xue-Gang Chen, Li-Chun Tseng, Elizabeth M. Jones, Debora Iglesias-Rodriguez, Pascal Bailly du Bois, Christopher D. Payne, Paz Jimenez, Ana de Lara, Benjamin S. Twining, Carin J. Ashjian, Laura Lorenzoni, Armindo F. da Silva, Ricardo Sanchez-Leal, Roberto Benavides, Nejib Daly Yahia, Miles D. Lamare, Dieter Garbe-Schönberg, Joan Enric Cartes, Ulrike Westernströer, Jacek Bełdowski, Mario Lebrato, Andreas Oschlies, Michelle Graco, Daniel O.B. Jones, Jiang-Shiou Hwang, Karen Bremer, Juan Carlos Molinero, Aurélien Paulmier, Kelly L. Robinson, Flavio Emiliano Paparazzo, Richard Webster, Richard A. Feely, Alexander Korablev, Steven Bell
Publikováno v:
Proceedings of the National Academy of Sciences (PNAS)
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, pp.201918943. ⟨10.1073/pnas.1918943117⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
22281-22292
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, pp.201918943. ⟨10.1073/pnas.1918943117⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
e-IEO. Repositorio Institucional Digital de Acceso Abierto del Instituto Español de Oceanografía
22281-22292
Proc Natl Acad Sci U S A
12 pages, 5 figures, supporting information https://doi.org/10.1073/pnas.1918943117.-- Data Availability. Our published databases are publicly accessible for readers, and they are deposited at the NOAA NCEI at https://data.nodc.noaa.gov/cgi-bin/iso?i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b97c906adeb22fd68845bb74bda788
https://hdl.handle.net/11250/2735695
https://hdl.handle.net/11250/2735695
Autor:
Enaksha R, Wickremsinhe, Scott M, Hynes, Christopher D, Payne, Yingying, Guo, Kenneth C, Cassidy
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 50(7)
The disposition and metabolism of prexasertib, a CHK-1 inhibitor was characterised over a 120 h period following a single 170-mg intravenous dose of [
Autor:
Maria M. Posada, Christopher D. Payne, Xin Zhang, Stephen D. Hall, J. William Higgins, Ellen A. Cannady, Y. Anne Pak, Nazila Shahri, Kathleen M. Hillgren, James A. Bacon
Publikováno v:
Clinical and Translational Science
Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, undergoes active renal tubular secretion. Baricitinib was not predicted to inhibit hepatic and renal uptake and efflux drug transporters, based on the ratio of the unbound maximum elimina
Autor:
Alyse K. Hawley, Maya P. Bhatia, Elena Zaikova, Esther A. Gies, Sean A. Crowe, Jan F. Finke, Frank A. Whitney, David W. Capelle, Curtis A. Suttle, Melanie Scofield, Larysa Pakhomova, Philippe D. Tortell, Andreas Mueller, Céline Michiels, Steven J. Hallam, Christopher D. Payne, David A. Walsh, Diane Fairley, Olena Shevchuk, Mónica Torres-Beltrán, Sam Kheirandish
Publikováno v:
Scientific Data
Scientific Data, Vol 6, Iss 1, Pp 1-1 (2019)
Scientific Data, Vol 6, Iss 1, Pp 1-1 (2019)
Extensive and expanding oxygen minimum zones (OMZs) exist at variable depths in coastal and open ocean waters. As oxygen levels decline, nutrients and energy are increasingly diverted away from higher trophic levels into microbial community metabolis