Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher D. O. Cooper"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/4f4f8762a53e435fad4176983727f957
Autor:
Qiang Tong, Ying Zhu, Dandan Zhang, Qing Cai, Wenchun Qu, Christopher D. O. Cooper, Jiaqi Wang, Patrick C. McHugh
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 2, Pp 793-811 (2018)
Background/Aims: MicroRNA (miRNA)-induced suppression of dendritic cells (DCs) has been implicated in many diseases. Therefore, accurate monitoring of miRNA endocytosis by DCs is important for understanding the role of miRNAs in many diseases. Recent
Externí odkaz:
https://doaj.org/article/50f2e316935f46fd976945cf574666f5
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
ZRANB3 (Zinc-finger, RAN-Binding domain containing 3) is a structure-specific endonuclease that is recruited to DNA breaks and stressed replication forks. Here the authors present the crystal structure of the ZRANB3 endonuclease domain and analyse ho
Externí odkaz:
https://doaj.org/article/e255a9bc2f6248c5a18735606cd0c8fe
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1586
Soluble protein expression is a key requirement for biochemical and structural biology approaches to study biological systems in vitro. Production of sufficient quantities may not always be achievable if proteins are poorly soluble which is frequentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bddf4b6c32d3bfca73271daf909af2de
https://pubmed.ncbi.nlm.nih.gov/28470596
https://pubmed.ncbi.nlm.nih.gov/28470596
Publikováno v:
Structure(London, England:1993)
Summary DNA polymerase theta (Polθ) has been identified as a crucial alternative non-homologous end-joining factor in mammalian cells. Polθ is upregulated in a range of cancer cell types defective in homologous recombination, and knockdown has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad3b7983e25b53ef8b8fb5f27c50359d
https://pubmed.ncbi.nlm.nih.gov/26636256
https://pubmed.ncbi.nlm.nih.gov/26636256
Publikováno v:
The Journal of Biological Chemistry
Background: ETS transcription factors regulate expression of genes involved in development and cancer. Results: Crystal structure of the Ets-2 DNA binding domain reveals how closely spaced binding sites are recognized. Conclusion: A significant diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8bce363ae2cd9989cbce8cfe79742991
https://pubmed.ncbi.nlm.nih.gov/25670864
https://pubmed.ncbi.nlm.nih.gov/25670864
Publikováno v:
Biochemical Society Transactions
The Ets family of eukaryotic transcription factors is based around the conserved Ets DNA-binding domain. Although their DNA-binding selectivity is biochemically and structurally well characterized, structures of homodimeric and ternary complexes poin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3edc2837445d2a401823900e2f91850c
https://pubmed.ncbi.nlm.nih.gov/24450640
https://pubmed.ncbi.nlm.nih.gov/24450640
Autor:
Stephen R F, Twigg, Deborah, Lloyd, Dagan, Jenkins, Nursel E, Elçioglu, Christopher D O, Cooper, Nouriya, Al-Sannaa, Ali, Annagür, Gabriele, Gillessen-Kaesbach, Irina, Hüning, Samantha J L, Knight, Judith A, Goodship, Bernard D, Keavney, Philip L, Beales, Opher, Gileadi, Simon J, McGowan, Andrew O M, Wilkie
Publikováno v:
American journal of human genetics. 91(5)
Carpenter syndrome is an autosomal-recessive multiple-congenital-malformation disorder characterized by multisuture craniosynostosis and polysyndactyly of the hands and feet; many other clinical features occur, and the most frequent include obesity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b9e996527f782c0f2030b2928de1d1e
https://pubmed.ncbi.nlm.nih.gov/23063620
https://pubmed.ncbi.nlm.nih.gov/23063620
Autor:
Joseph A Newman, Christopher D O Cooper, Anette K Roos, Hazel Aitkenhead, Udo C T Oppermann, Hearn J Cho, Roman Osman, Opher Gileadi
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148762 (2016)
The MAGE (melanoma associated antigen) protein family are tumour-associated proteins normally present only in reproductive tissues such as germ cells of the testis. The human genome encodes over 60 MAGE genes of which one class (containing MAGE-A3 an
Externí odkaz:
https://doaj.org/article/44063d5312b248f0a13c8fa7257d4839
Autor:
Christopher D O Cooper, Charles H Lawrie, Amanda P Liggins, Graham P Collins, Christian S R Hatton, Karen Pulford, Alison H Banham
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23916 (2011)
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL). With notable excepti
Externí odkaz:
https://doaj.org/article/2def748344ba4f329720f34c6db3bad5