Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Christopher D. Nelson"'
Publikováno v:
Globalization and Health, Vol 19, Iss 1, Pp 1-4 (2023)
Abstract A number of scientific publications and commentaries have suggested that standard preparedness indices such as the Global Health Security Index (GHSI) and Joint External Evaluation (JEE) scores did not predict COVID-19 outcomes. To some, the
Externí odkaz:
https://doaj.org/article/5446d1d811ad47b5828643a8f4817477
Publikováno v:
BioTechniques, Vol 29, Iss 4, Pp 874-882 (2000)
An image analysis program and protocol for the identification and enumeration of live versus dead cells of the yeast-like fungus Aureobasidium pullulans was developed for both populations on microscope slides and leaf surfaces. Live cells took up Cel
Externí odkaz:
https://doaj.org/article/8e62d56c753043ae9e18b2ccda281664
Autor:
Wei Yang, Mari Christensen, Jennifer K. Chan, Julie Tsai, Nancy Patten, Ha B. Tran, Grant R. Hillman, Yu Chuan Tai, Patrick Bogard, Claudia M. Litterst, Victoria H. Brophy, Nick Newton, Christopher D. Nelson, Wouter J. Pattje
Publikováno v:
Cancer Research. 82:5156-5156
Non-small cell lung cancer (NSCLC) patients harboring activating mutations in epidermal growth factor receptor (EGFR) are benefited from Tyrosine Kinase Inhibitor (TKI) targeted therapy. However, more than 50% of patients receiving the first or secon
Autor:
Christopher D Nelson, Morgan Sheng
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74680 (2013)
The orphan G protein-coupled receptor (GPCR) GPR3 enhances the processing of Amyloid Precursor Protein (APP) to the neurotoxic beta-amyloid (Aβ) peptide via incompletely understood mechanisms. Through overexpression and shRNA knockdown experiments i
Externí odkaz:
https://doaj.org/article/a58c2e851a9e4c5f9d374287842cf5ab
Publikováno v:
Journal of Neuroscience. 33:12122-12135
Activity of glycogen synthase kinase-3β (GSK-3β) is required for long-term depression (LTD) via molecular mechanisms that are incompletely understood. Here, we report that PSD-95, a major scaffold protein of the postsynaptic density (PSD) that prom
Autor:
Gülin Öz, Harry T. Orr, Lynn E. Eberly, H. Brent Clark, Manda L. Vollmers, Ryan Shanley, Christopher D. Nelson
Publikováno v:
Experimental Neurology. 232:290-298
Reliable and objective markers of neuronal function and pathology that can directly assess the effects of neuroprotective treatments in the brain are urgently needed for clinical trials in neurodegenerative diseases. Here we assessed the sensitivity
Autor:
Gülin Öz, H. Brent Clark, Pierre-Gilles Henry, Christopher D. Nelson, Harry T. Orr, Lynn E. Eberly, Dinesh K. Deelchand, Małgorzata Marjańska, Dee M. Koski, Ryan Shanley
Publikováno v:
The Journal of Neuroscience. 30:3831-3838
Recent studies with a conditional mouse model of spinocerebellar ataxia type 1 (SCA1) suggest that neuronal dysfunction is reversible and neurodegeneration preventable with early interventions. Success of such interventions will depend on early detec
Autor:
Julien Valette, Dee M. Koski, Pierre-Gilles Henry, Dinesh K. Deelchand, Isabelle Iltis, Lynn E. Eberly, Kamil Ugurbil, Kelvin O. Lim, Christopher D. Nelson
Publikováno v:
NMR in Biomedicine. 22:737-744
Acute phencyclidine (PCP) administration mimics some aspects of schizophrenia in rats, such as behavioral alterations, increased dopaminergic activity and prefrontal cortex dysfunction. In this study, we used single-voxel 1H-MRS to investigate neuroc
Autor:
Christopher D. Nelson, Alexander A. Shestov, Kâmil Uğurbil, Pierre-Gilles Henry, Dinesh K. Deelchand
Publikováno v:
Journal of Magnetic Resonance. 196:157-163
In this work the feasibility of measuring neuronal-glial metabolism in rat brain in vivo using co-infusion of [1,6-(13)C(2)]glucose and [1,2-(13)C(2)]acetate was investigated. Time courses of (13)C spectra were measured in vivo while infusing both (1