Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Christopher D. Hillyer"'
Autor:
Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Lysine succinylation (Ksu) has recently emerged as a protein modification that regulates diverse functions in various biological processes. However, the systemically and precise role of lysine succinylation in erythropoiesis remains to be fully eluci
Externí odkaz:
https://doaj.org/article/f81da794426a468c8181758571cf6adc
Autor:
Daniel J. Nesbitt, Daniel P. Jin, Joseph W. Hogan, Jenny Yang, Haidee Chen, Philip A. Chan, Melissa J. Simon, Matthew Vargas, Ewa King, Richard C. Huard, Utpala Bandy, Christopher D. Hillyer, Larry L. Luchsinger
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Epidemic projections and public health policies addressing Coronavirus disease (COVID)-19 have been implemented without data reporting on the seroconversion of the population since scalable antibody testing has only recently becom
Externí odkaz:
https://doaj.org/article/2e00c149b25f4383b00c03f108d19bb8
Autor:
Francesca Curreli, Kent Chau, Thanh-Thuy Tran, Isabella Nicolau, Shahad Ahmed, Pujita Das, Christopher D. Hillyer, Mary Premenko-Lanier, Asim K. Debnath
Publikováno v:
Viruses, Vol 15, Iss 4, p 1001 (2023)
The unprecedented pandemic of COVID-19, caused by a novel coronavirus, SARS-CoV-2, and its highly transmissible variants, led to massive human suffering, death, and economic devastation worldwide. Recently, antibody-evasive SARS-CoV-2 subvariants, BQ
Externí odkaz:
https://doaj.org/article/c53028b7761f4c8395a20977fa827cf7
Autor:
Brett Ragnesola, Daniel Jin, Christopher C. Lamb, Beth H. Shaz, Christopher D. Hillyer, Larry L. Luchsinger
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Objective COVID19 has caused a global and ongoing pandemic. The need for population seroconversion data is apparent to monitor and respond to the pandemic. Using a lateral flow assay (LFA) testing platform, the seropositivity in 63 New York
Externí odkaz:
https://doaj.org/article/3f9db0dcba6945eabecb513a779e73b1
Autor:
Francesca Curreli, Sofia M. B. Victor, Shahad Ahmed, Aleksandra Drelich, Xiaohe Tong, Chien-Te K. Tseng, Christopher D. Hillyer, Asim K. Debnath
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT SARS-CoV-2 uses human angiotensin-converting enzyme 2 (ACE2) as the primary receptor to enter host cells and initiate the infection. The critical binding region of ACE2 is an ∼30-amino-acid (aa)-long helix. Here, we report the design of fo
Externí odkaz:
https://doaj.org/article/7459b0c8aaa2467f833de234e555f435
Autor:
Yumin Huang, John Hale, Yaomei Wang, Wei Li, Shijie Zhang, Jieying Zhang, Huizhi Zhao, Xinhua Guo, Jing Liu, Hongxia Yan, Karina Yazdanbakhsh, Gang Huang, Christopher D. Hillyer, Narla Mohandas, Lixiang Chen, Ling Sun, Xiuli An
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background SF3B1 is a core component of splicing machinery. Mutations in SF3B1 are frequently found in myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ringed sideroblasts (RARS), characterized by isolate
Externí odkaz:
https://doaj.org/article/98f9bee7930c4d9a9b6d0398d4715a64
Autor:
Francesca Curreli, Shahad Ahmed, Sofia M. B. Victor, Aleksandra Drelich, Siva S. Panda, Andrea Altieri, Alexander V. Kurkin, Chien-Te K. Tseng, Christopher D. Hillyer, Asim K. Debnath
Publikováno v:
Viruses, Vol 14, Iss 1, p 69 (2021)
We report the discovery of several highly potent small molecules with low-nM potency against severe acute respiratory syndrome coronavirus (SARS-CoV; lowest half-maximal inhibitory concentration (IC50: 13 nM), SARS-CoV-2 (IC50: 23 nM), and Middle Eas
Externí odkaz:
https://doaj.org/article/447c4795eeaa4a548022ea9c515c5a92
Autor:
Long Liang, Yuanliang Peng, Jieying Zhang, Yibin Zhang, Mridul Roy, Xu Han, Xiaojuan Xiao, Shuming Sun, Hong Liu, Ling Nie, Yijin Kuang, Zesen Zhu, Jinghui Deng, Yang Xia, Vijay G. Sankaran, Christopher D. Hillyer, Narla Mohandas, Mao Ye, Xiuli An, Jing Liu
Publikováno v:
Haematologica, Vol 104, Iss 11 (2019)
Ubiquitination is an enzymatic post-translational modification that affects protein fate. The ubiquitin-proteasome system (UPS) was first discovered in reticulocytes where it plays important roles in reticulocyte maturation. Recent studies have revea
Externí odkaz:
https://doaj.org/article/a9d1e298d7b24f4b8109db8a9bf2c245
Autor:
Vincent P. Schulz, Hongxia Yan, Kimberly Lezon-Geyda, Xiuli An, John Hale, Christopher D. Hillyer, Narla Mohandas, Patrick G. Gallagher
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2996-3009.e7 (2019)
Summary: Mammalian erythropoiesis yields a highly specialized cell type, the mature erythrocyte, evolved to meet the organismal needs of increased oxygen-carrying capacity. To better understand the regulation of erythropoiesis, we performed genome-wi
Externí odkaz:
https://doaj.org/article/a9c2a7eead4f4429becbce4ae6c2c224
Publikováno v:
Stem Cells International, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/6237cd7260b64ece9c48ff31c48cacc5