Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Christopher D. Hardin"'
Autor:
Kevin L. Fritsche, Grace M. Meers, Christopher D. Hardin, John P. Thyfault, Jamal A. Ibdah, E. Matthew Morris, Frank W. Booth
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G979-G992
Studies have shown that decreased mitochondrial content and function are associated with hepatic steatosis. We examined whether peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) overexpression and a subsequent increase in mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcd9d71711604022864dee8c3d58a68
https://doi.org/10.1152/ajpgi.00169.2012
https://doi.org/10.1152/ajpgi.00169.2012
Autor:
Johana Vallejo, Christopher D. Hardin
Publikováno v:
Biochemistry. 43:16224-16232
Using confocal microscopy, we have demonstrated a similar distribution of phosphofructokinase (PFK) with caveolin-1 (CAV-1) mainly at the periphery (membrane) in freshly isolated vascular smooth muscle (VSM) cells and in cultured A7r5 VSM cells. Co-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87513728cbb49d6237c4f47dcc381030
https://doi.org/10.1021/bi0490035
https://doi.org/10.1021/bi0490035
Autor:
Christopher D. Hardin, Pamela G. Lloyd
Publikováno v:
American Journal of Physiology-Cell Physiology. 300:C232-C234
caveolae are flask-shaped invaginations on cholesterol- and sphingolipid-rich domains of the plasma membrane that have been proposed to play a role in the localization of a wide range of signaling systems and metabolic pathways in a variety of cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40fb7a9d1b2a8eba18f5163a1713877b
https://doi.org/10.1152/ajpcell.00483.2010
https://doi.org/10.1152/ajpcell.00483.2010
Autor:
Bruno Giardina, Donato Di Pierro, Tina M. Roberts, Barbara Tavazzi, Michael J. Rovetto, Giuseppe Lazzarino, Christopher D. Hardin
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
The extent to and the mechanism by which fructose-1,6-bisphosphate (FDP) crosses cell membranes are unknown. We hypothesized that its transport is either via band 3 or a dicarboxylate transporter. The question was addressed in isolated Langendorff ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a8b40167f9ad0be0d24cb76d256ce4
https://doi.org/10.1152/ajpheart.2001.281.6.h2654
https://doi.org/10.1152/ajpheart.2001.281.6.h2654
Autor:
Christopher D. Hardin, Pamela G. Lloyd
Publikováno v:
Journal of Cellular Biochemistry. 82:399-408
We have previously found that glycolysis and gluconeogenesis occur in separate “compartments” of the VSM cell. These compartments may result from spatial separation of glycolytic and gluconeogenic enzymes (Lloyd and Hardin [1999] Am J Physiol Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638b9dd134e251b866da8e045a0d68f0
https://doi.org/10.1002/jcb.1170
https://doi.org/10.1002/jcb.1170
Publikováno v:
Molecular and Cellular Biochemistry. 217:99-106
High cholesterol, especially LDL cholesterol, has been associated with the development of atherosclerotic plaques in arteries. To investigate the changes in cellular substrate metabolism early in the atherogenic process, Sinclair miniature swine were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4f20f2c5654091ab5ac72c8e32a3ce
https://doi.org/10.1023/a:1007208326027
https://doi.org/10.1023/a:1007208326027
Autor:
Pamela G. Lloyd, Christopher D. Hardin
Publikováno v:
American Journal of Physiology-Cell Physiology. 278:C803-C811
We used β-escin-permeabilized pig cerebral microvessels (PCMV) to study the organization of carbohydrate metabolism in the cytoplasm of vascular smooth muscle (VSM) cells. We have previously demonstrated (Lloyd PG and Hardin CD. Am J Physiol Cell Ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::117e5e08a13be055c8f3eecb3f037419
https://doi.org/10.1152/ajpcell.2000.278.4.c803
https://doi.org/10.1152/ajpcell.2000.278.4.c803
Autor:
Johana Vallejo, Christopher D. Hardin
Publikováno v:
American Journal of Physiology-Cell Physiology. 296:C387-C389
the centrality of protein complexes and transient protein-protein interactions in cellular physiology is becoming increasingly clear. Although one can readily demonstrate protein-protein interactions with nonphysiological approaches such as immunopre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e37e8c83d2e703e94a57f8deab9cc95c
https://doi.org/10.1152/ajpcell.00663.2008
https://doi.org/10.1152/ajpcell.00663.2008
Publikováno v:
Molecular and Cellular Biochemistry. 195:113-121
The keto (linear) form of exogenous fructose 1,6-bisphosphate, a highly charged glycolytic intermediate, may utilize a dicarboxylate transporter to cross the cell membrane, support glycolysis, and produce ATP anaerobically. We tested the hypothesis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fcd76e8cae0c95a63898f75f13f35d
https://doi.org/10.1023/a:1006976432578
https://doi.org/10.1023/a:1006976432578
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C88-C96
To determine whether channeling of glycolytic intermediates can occur in vascular smooth muscle (VSM), we permeabilized freshly isolated VSM cells from hog carotid arteries with dextran sulfate. The dextran sulfate-treated cells did not exclude trypa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7816f04917fb052e5a698d628f730a6
https://doi.org/10.1152/ajpcell.1998.274.1.c88
https://doi.org/10.1152/ajpcell.1998.274.1.c88