Predator-secreted sulfolipids induce defensive responses in C. elegans

Autor: Zheng Liu, Maro J. Kariya, Christopher D. Chute, Amy K. Pribadi, Sarah G. Leinwand, Ada Tong, Kevin P. Curran, Neelanjan Bose, Frank C. Schroeder, Jagan Srinivasan, Sreekanth H. Chalasani

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Defensive behavioral responses can be triggered by predator-released odors. Here, the authors identified the relevant Pristionchus pacificus-released sulfolipid molecules and dissected the neural circuits underlying C. elegans response to this predat

Externí odkaz: https://doaj.org/article/15b6645a0d3c438aa0f7c65f94dc1b17

Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

Autor: Hee June Choi, Douglas K. Reilly, Elizabeth M. DiLoreto, Mark J. Alkema, Diego Hernán Rayes, Ying K. Zhang, Christopher D. Chute, Veronica L. Coyle, Frank C. Schroeder, Jagan Srinivasan

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
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Nature Communications

Biogenic amine neurotransmitters play a central role in metazoan biology, and both their chemical structures and cognate receptors are evolutionarily conserved. Their primary roles are in cell-to-cell signaling, as biogenic amines are not normally re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7227699c555ecee37a438e76134fa94
https://doi.org/10.1038/s41467-019-11240-7

Functional Connectomics in C. elegans

Autor: Samantha Bryce, Christopher D. Chute, Elizabeth M. DiLoreto, Jagan Srinivasan

The completestructure and connectivity of the Caenorhabditis elegansnervous system was first published in 1986. The ‘mind of a worm’ was the first organism to have its nervous system to be reconstructed at the level of synapses, and represented a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f29e986b63a634e538c34741af70576
https://doi.org/10.20944/preprints201811.0038.v1

Predator-secreted sulfolipids induce fear-like defense responses in C. elegans

Autor: Ada Tong, Kevin P. Curran, Sreekanth H. Chalasani, Neelanjan Bose, Zheng Liu, Jagan Srinivasan, Amy K. Pribadi, Sarah G Leinwand, Frank C. Schroeder, Christopher D. Chute, Maro J. Kariya

Animals respond to predators by altering their behavior and physiological states, but the underlying signaling mechanisms are poorly understood. Using the interactions between Caenorhabditis elegans and its predator, Pristionchus pacificus, we show t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac0506815552af034aaf5efc794233b
https://doi.org/10.1101/153056

POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA

Autor: Zhirong Bao, Ahmed Elewa, Christopher D. Chute, Dongni Yi, Ebru Kaymak, Paul Harrison, Craig C. Mello, Zhuo Du, David R. Powell, Takao Ishidate, Sean P. Ryder, Jagan Srinivasan, Masaki Shirayama, Hannah Woolf, Traude H. Beilharz

Publikováno v: Developmental Cell. (1):108-118

Summary The regulation of mRNA translation is of fundamental importance in biological mechanisms ranging from embryonic axis specification to the formation of long-term memory. POS-1 is one of several CCCH zinc-finger RNA-binding proteins that regula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276e459d7c60ff59d0a3e2b83bcea798