Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Christopher D. Bertram"'
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 2, Pp 1406-1424 (2021)
A majority of lymphatic valves tend to form in proximity to vessel junctions, and it is often proposed that disturbed flow at junctions creates oscillating shear stress that leads to accumulation of transcription factors which bring about valvogenesi
Externí odkaz:
https://doaj.org/article/7c04720f2c514bb38b44bbf7ce1aeb75
Publikováno v:
Biology, Vol 12, Iss 3, p 379 (2023)
Lymphatic valves operate in a fluid-dynamically viscous environment that has little in common with that of cardiac valves, and accordingly have a different, axially lengthened, shape. A previously developed 3D fluid/structure interaction model of a l
Externí odkaz:
https://doaj.org/article/1ca1b0f5859c4b4daa5e1aec590267f8
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 2, Pp 1406-1424 (2021)
A majority of lymphatic valves tend to form in proximity to vessel junctions, and it is often proposed that disturbed flow at junctions creates oscillating shear stress that leads to accumulation of transcription factors which bring about valvogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9e6f62c5d98d51d2dca5dfcc9f4907
http://www.aimspress.com/article/doi/10.3934/mbe.2021073?viewType=HTML
http://www.aimspress.com/article/doi/10.3934/mbe.2021073?viewType=HTML
Autor:
Christopher D. Bertram, Scott D. Zawieja, Michael J. Davis, Edward J. Hancock, Charles Macaskill
Lymphoedema develops due to chronic dysfunction of the lymphatic vascular system which results in fluid accumulation between cells. The condition is commonly acquired secondary to diseases such as cancer or the therapies associated with it. The prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c1755e16fdc53f535c8d82614c00cb
https://doi.org/10.1101/2021.11.07.467629
https://doi.org/10.1101/2021.11.07.467629
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 19:677-679
In the published paper, we argued that, although there appear to be no data available on the subject, it is inherently unlikely that lymph having traversed a network of initial lymphatics and pre-collectors then encounters an abrupt transition to ves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1521cb4841622bb539e8c1b4ab53127d
https://doi.org/10.1007/s10237-020-01303-w
https://doi.org/10.1007/s10237-020-01303-w
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 17:1513-1532
The paper describes the extension of a previously developed model of pressure-dependent contraction rate to the case of multiple lymphangions. Mechanical factors are key modulators of active lymphatic pumping. As part of the evolution of our lumped-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9938f3a7c74d90f289964d72f3457224
https://doi.org/10.1007/s10237-018-1042-7
https://doi.org/10.1007/s10237-018-1042-7
Publikováno v:
Biomechanics and Modeling in Mechanobiology. 16:1987-2003
Lymph is transported along collecting lymphatic vessels by intrinsic and extrinsic pumping. The walls have muscle of a type intermediate between blood-vascular smooth muscle and myocardium; a contracting segment between two valves (a lymphangion) con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e61434ec0b751ffee1cde123baa038e
https://doi.org/10.1007/s10237-017-0933-3
https://doi.org/10.1007/s10237-017-0933-3
Autor:
Christopher D. Bertram
Publikováno v:
Biomech Model Mechanobiol
A three-dimensional finite-element fluid/structure interaction model of an intravascular lymphatic valve was constructed, and its properties were investigated under both favourable and adverse pressure differences, simulating valve opening and valve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57f5bb61956e629422288849e95efba
https://pubmed.ncbi.nlm.nih.gov/32303880
https://pubmed.ncbi.nlm.nih.gov/32303880
Publikováno v:
Biomech Model Mechanobiol
Initial lymphatic vessels are made up of overlapped endothelial cells that act as unidirectional valves enabling one-way drainage of tissue fluid into the lumen of the initial lymphatics when there is a favourable pressure gradient. Initial lymphatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddc7575cf393051d1f09558d7a92077
https://pubmed.ncbi.nlm.nih.gov/32072372
https://pubmed.ncbi.nlm.nih.gov/32072372
Publikováno v:
J Biomech Eng
The phasic contractions of collecting lymphatic vessels are reduced in strength and occur at diminished frequency when a favorable pressure difference and the resulting antegrade flow create large fluid shear stresses at the luminal surface. This pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35051abcdbc55ea3e91d1b5770f82c8b
https://pubmed.ncbi.nlm.nih.gov/31074761
https://pubmed.ncbi.nlm.nih.gov/31074761