Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Christopher D Katanski"'
Publikováno v:
eLife, Vol 9 (2020)
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thou
Externí odkaz:
https://doaj.org/article/97f1c9ac38f7443a8b8ae635218967bc
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
This paper develops a multiplex RNA-seq method that reports tRNA abundance, modification, charging, and fragmentation. Results show stress-induced regulation in translational elongation and association of modification and tRNA fragment biogenesis.
Externí odkaz:
https://doaj.org/article/71d4401718c8473fb3cbaecdca743cef
Autor:
Sihao Huang, Wen Zhang, Christopher D. Katanski, Devin Dersh, Qing Dai, Karen Lolans, Jonathan Yewdell, A. Murat Eren, Tao Pan
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Pseudouridine (Ψ) is an abundant mRNA modification in mammalian transcriptome, but its functions have remained elusive due to the difficulty of transcriptome-wide mapping. We develop a nanopore native RNA sequencing method for quantitative
Externí odkaz:
https://doaj.org/article/c2174ae8a7ba43d59f1fde52b05e3832
Autor:
Christopher D. Katanski, Hala Alshammary, Christopher P. Watkins, Sihao Huang, Ana Gonzales-Reiche, Emilia Mia Sordillo, Harm van Bakel, Mount Sinai PSP study group, Karen Lolans, Viviana Simon, Tao Pan, Shelcie Fabre, Jose Polanco, Matthew M. Hernandez, Alberto Paniz-Mondolfi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Emerging and re-emerging respiratory viruses can spread rapidly and cause pandemics as demonstrated by the recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The early human immune responses to respiratory viruses are in th
Externí odkaz:
https://doaj.org/article/903b34e3d8e6413ba9b2a30034e0a137
Autor:
Behnam Javidfar, Wei-Dong Yao, Fatemeh Haghighi, M. Foo, C. P. Watkins, C. G. Hahn, Søren Heissel, H. L. Phillips, Schahram Akbarian, Sohit Miglani, Jennifer Blaze, Henrik Molina, B. Rostandy, Zachary T. Pennington, Albertas Navickas, Tao Pan, Hani Goodarzi, Denise J. Cai, Hanan Alwaseem, A. Plaza-Jennings, Sergio Espeso-Gil, Christopher D. Katanski, Hosseinali Asgharian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Epitranscriptomic mechanisms linking tRNA function and the brain proteome to cognition and complex behaviors are not well described. Here, we report bi-directional changes in depression-related behaviors after genetic disruption of neuronal tRNA cyto
Autor:
Sihao Huang, Wen Zhang, Christopher D. Katanski, Tao Pan, Dai Qing, Karen Lolans, A. M. Eren, Devin Dersh, Jonathan Yewdell
Publikováno v:
The FASEB Journal. 36
Autor:
Xavier Hernandez-Alias, Christopher D Katanski, Wen Zhang, Mahdi Assari, Christopher P Watkins, Martin H Schaefer, Luis Serrano, Tao Pan
Publikováno v:
Nucleic Acids Research. 51:e17-e17
Transfer RNA (tRNA) utilizes multiple properties of abundance, modification, and aminoacylation in translational regulation. These properties were typically studied one-by-one; however, recent advance in high throughput tRNA sequencing enables their
Autor:
Christopher D Katanski, Christopher P Watkins, Wen Zhang, Matthew Reyer, Samuel Miller, Tao Pan
Publikováno v:
Nucleic Acids Research. 50:e99-e99
Queuosine (Q) is a conserved tRNA modification at the wobble anticodon position of tRNAs that read the codons of amino acids Tyr, His, Asn, and Asp. Q-modification in tRNA plays important roles in the regulation of translation efficiency and fidelity
Autor:
Jessica N. Pan, Christopher D. Katanski, Yuru Wang, Zhuoxun Jiang, Chris Watkins, Tao Pan, Qing Dai
Publikováno v:
Nucleic Acids Research
AlkB is a DNA/RNA repair enzyme that removes base alkylations such as N1-methyladenosine (m1A) or N3-methylcytosine (m3C) from DNA and RNA. The AlkB enzyme has been used as a critical tool to facilitate tRNA sequencing and identification of mRNA modi
Publikováno v:
eLife, Vol 9 (2020)
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat-shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thou