Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Christopher D Green"'
Autor:
Christopher D. Green, Ryan D.R. Brown, Baasanjav Uranbileg, Cynthia Weigel, Sumit Saha, Makoto Kurano, Yutaka Yatomi, Sarah Spiegel
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101971- (2024)
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality, and its incidence is increasing due to endemic obesity. HCC is sexually dimorphic in both humans and rodents with higher incidence in males, although the mechan
Externí odkaz:
https://doaj.org/article/0d27976db3474a0b8686c16ec6a18ec0
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74074 (2013)
A routine approach to inferring functions for a gene set is by using function enrichment analysis based on GO, KEGG or other curated terms and pathways. However, such analysis requires the existence of overlapping genes between the query gene set and
Externí odkaz:
https://doaj.org/article/a7a16ef67cf243cca6075ef4709ef814
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1002998 (2013)
Identifying drug-drug interactions (DDIs) is a major challenge in drug development. Previous attempts have established formal approaches for pharmacokinetic (PK) DDIs, but there is not a feasible solution for pharmacodynamic (PD) DDIs because the end
Externí odkaz:
https://doaj.org/article/468eec5f121e4121a60e8a6b1411bdf9
Autor:
Fang Chen, Wei Zhang, Yu Liang, Jialiang Huang, Kui Li, Christopher D Green, Jiancheng Liu, Guojie Zhang, Bing Zhou, Xin Yi, Wei Wang, Hang Liu, Xiaohong Xu, Feng Shen, Ning Qu, Yading Wang, Guoyi Gao, A San, LuoSang JiangBai, Hua Sang, Xiangdong Fang, Karsten Kristiansen, Huanming Yang, Jun Wang, Jing-Dong J Han, Jian Wang
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31645 (2012)
Extreme altitude can induce a range of cellular and systemic responses. Although it is known that hypoxia underlies the major changes and that the physiological responses include hemodynamic changes and erythropoiesis, the molecular mechanisms and si
Externí odkaz:
https://doaj.org/article/07ad80ec5b1947c798b004775b2fe8e2
Autor:
Ryan D.R. Brown, Christopher D. Green, Cynthia Weigel, Bin Ni, Francesco S. Celi, Richard L. Proia, Sarah Spiegel
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101851- (2024)
Objective: The bioactive sphingolipid metabolites ceramide and sphingosine-1-phosphate (S1P) accumulate with overnutrition and have been implicated in non-alcoholic steatohepatitis (NASH) development. ORMDL3, a negative regulator of the rate-limiting
Externí odkaz:
https://doaj.org/article/04df4b65ed0b4cec8e9b5a778f50431d
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15078 (2023)
Diabetic cardiomyopathy is a critical diabetes-mediated co-morbidity characterized by cardiac dysfunction and heart failure, without predisposing hypertensive or atherosclerotic conditions. Metabolic insulin resistance, promoting hyperglycemia and hy
Externí odkaz:
https://doaj.org/article/7699f0de7eb649d5b144116cddc6bd6e
Autor:
Cynthia Weigel, Melissa A. Maczis, Elisa N.D. Palladino, Christopher D. Green, Michael Maceyka, Chunqing Guo, Xiang-Yang Wang, Mikhail G. Dozmorov, Sheldon Milstien, Sarah Spiegel
Publikováno v:
Cancer Research. 83:553-567
Reciprocal interactions between breast cancer cells and the tumor microenvironment (TME) are important for cancer progression and metastasis. We report here that the deletion or inhibition of sphingosine kinase 2 (SphK2), which produces sphingosine-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04dc41909a58f559d36f08a306fdaee
https://doi.org/10.1158/0008-5472.can-22-1638
https://doi.org/10.1158/0008-5472.can-22-1638
Autor:
Christopher D. Green
Publikováno v:
Historiography and the Formation of Philosophical Canons ISBN: 9781003184294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadb208105526868e9bd722d35fa1806
https://doi.org/10.4324/9781003184294-15
https://doi.org/10.4324/9781003184294-15
Autor:
Sarah Spiegel, Sheldon Milstien, Mikhail G. Dozmorov, Xiang-Yang Wang, Chunqing Guo, Michael Maceyka, Christopher D. Green, Elisa N.D. Palladino, Melissa A. Maczis, Cynthia Weigel
Reciprocal interactions between breast cancer cells and the tumor microenvironment (TME) are important for cancer progression and metastasis. We report here that the deletion or inhibition of sphingosine kinase 2 (SphK2), which produces sphingosine-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266a0a98f21e719e905f6c23c8b66628
https://doi.org/10.1158/0008-5472.c.6514374
https://doi.org/10.1158/0008-5472.c.6514374
Autor:
Sarah Spiegel, Sheldon Milstien, Mikhail G. Dozmorov, Xiang-Yang Wang, Chunqing Guo, Michael Maceyka, Christopher D. Green, Elisa N.D. Palladino, Melissa A. Maczis, Cynthia Weigel
ADDITIONAL MATERIALS AND METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04377152bdea2ea4441e82dfea7e0969
https://doi.org/10.1158/0008-5472.22433493.v1
https://doi.org/10.1158/0008-5472.22433493.v1