Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Christopher D, Pilcher"'
Autor:
Eduard Grebe, Shelley N. Facente, Jeremy Bingham, Christopher D. Pilcher, Andrew Powrie, Jarryd Gerber, Gareth Priede, Trust Chibawara, Michael P. Busch, Gary Murphy, Reshma Kassanjee, Alex Welte, on behalf of the Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA)
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background It is frequently of epidemiological and/or clinical interest to estimate the date of HIV infection or time-since-infection of individuals. Yet, for over 15 years, the only widely-referenced infection dating algorithm that utilises
Externí odkaz:
https://doaj.org/article/46940c648ac54a54a8cf6d8e124d4c45
Autor:
Rachel L. Rutishauser, Christian Deo T. Deguit, Joseph Hiatt, Franziska Blaeschke, Theodore L. Roth, Lynn Wang, Kyle A. Raymond, Carly E. Starke, Joseph C. Mudd, Wenxuan Chen, Carolyn Smullin, Rodrigo Matus-Nicodemos, Rebecca Hoh, Melissa Krone, Frederick M. Hecht, Christopher D. Pilcher, Jeffrey N. Martin, Richard A. Koup, Daniel C. Douek, Jason M. Brenchley, Rafick-Pierre Sékaly, Satish K. Pillai, Alexander Marson, Steven G. Deeks, Joseph M. McCune, Peter W. Hunt
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Although many HIV cure strategies seek to expand HIV-specific CD8+ T cells to control the virus, all are likely to fail if cellular exhaustion is not prevented. A loss in stem-like memory properties (i.e., the ability to proliferate and generate seco
Externí odkaz:
https://doaj.org/article/1a92cd130be447828fcd995ae89a3b10
Autor:
Shelley N. Facente, Michael P. Busch, Eduard Grebe, Christopher D. Pilcher, Alex Welte, Brian Rice, Gary Murphy
Publikováno v:
Gates Open Research, Vol 3 (2019)
Background: New challenges for diagnosis of HIV infection abound, including the impact on key viral and immunological markers of HIV vaccine studies, pre-exposure prophylaxis usage and breakthrough infections, and very early initiation of anti-retrov
Externí odkaz:
https://doaj.org/article/3f7e7078196041678d7bf37126f831f4
Autor:
Joseph B Sempa, Alex Welte, Michael P Busch, Jake Hall, Dylan Hampton, Shelley N Facente, Sheila M Keating, Kara Marson, Neil Parkin, Christopher D Pilcher, Gary Murphy, Eduard Grebe, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA)
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220345 (2019)
BackgroundTwo manufacturers, Maxim Biomedical and Sedia Biosciences Corporation, supply CDC-approved versions of the HIV-1 Limiting Antigen Avidity EIA (LAg) for detecting 'recent' HIV infection in cross-sectional incidence estimation. This study ass
Externí odkaz:
https://doaj.org/article/d84c3385c34e4c6ca1a449a372057bd7
Autor:
Christopher D. Pilcher, Javier R. Lama, Sayan Dasgupta, Serena Spudich, Siavash Pasalar, Ann Duerr, Sheila M. Keating, Rogelio Valdez, Kevin Robertson, Rachel A Bender Ignacio, August A Longino, Eduardo Ruiz, Yixin Wang, Cecilia Correa, Robert H. Paul, Peter Brandes, Alyssa Vecchio
Publikováno v:
J Acquir Immune Defic Syndr
Introduction Early systemic and central nervous system viral replication and inflammation may impact brain integrity in people with HIV (PWH), leading to chronic cognitive symptoms not fully reversed by antiretroviral therapy (ART). This study examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb4cbaa96254a3bc6705523cf1404a6
https://doi.org/10.1097/qai.0000000000002832
https://doi.org/10.1097/qai.0000000000002832
Autor:
Ivan Vujkovic-Cvijin, Louise A. Swainson, Simon N. Chu, Alexandra M. Ortiz, Clark A. Santee, Annalise Petriello, Richard M. Dunham, Douglas W. Fadrosh, Din L. Lin, Ali A. Faruqi, Yong Huang, Cristian Apetrei, Ivona Pandrea, Frederick M. Hecht, Christopher D. Pilcher, Nichole R. Klatt, Jason M. Brenchley, Susan V. Lynch, Joseph M. McCune
Publikováno v:
Cell Reports, Vol 13, Iss 8, Pp 1589-1597 (2015)
Gut microbes can profoundly modulate mucosal barrier-promoting Th17 cells in mammals. A salient feature of HIV/simian immunodeficiency virus (SIV) immunopathogenesis is the loss of Th17 cells, which has been linked to increased activity of the immuno
Externí odkaz:
https://doaj.org/article/fb31f9d241b44042a7d4c58865400f8a
Autor:
Nadia R Roan, Nathallie Sandi-Monroy, Nargis Kohgadai, Shariq M Usmani, Katherine G Hamil, Jason Neidleman, Mauricio Montano, Ludger Ständker, Annika Röcker, Marielle Cavrois, Jared Rosen, Kara Marson, James F Smith, Christopher D Pilcher, Friedrich Gagsteiger, Olena Sakk, Michael O’Rand, Polina V Lishko, Frank Kirchhoff, Jan Münch, Warner C Greene
Publikováno v:
eLife, Vol 6 (2017)
Unlike other human biological fluids, semen contains multiple types of amyloid fibrils in the absence of disease. These fibrils enhance HIV infection by promoting viral fusion to cellular targets, but their natural function remained unknown. The simi
Externí odkaz:
https://doaj.org/article/5f637bd10286422c90ea408f595c4cda
Autor:
Gina Faraci, Christopher D. Pilcher, Gary Murphy, Sung Yong Park, Ha Youn Lee, Michael P. Busch
Publikováno v:
J Infect Dis
Background Precise and cost-efficient human immunodeficiency virus (HIV) incidence and drug resistance surveillances are in high demand for the advancement of the 90-90-90 “treatment for all” target. Methods We developed microdrop HIV sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837911ceeb66cab078ff9753b8f50b01
https://doi.org/10.1093/infdis/jiab060
https://doi.org/10.1093/infdis/jiab060
Autor:
Wendy Hartogensis, Yanpeng Li, Eric Delwart, Frederick Hecht, Eda Altan, Xutao Deng, Christopher D. Pilcher
Publikováno v:
AIDS. 34:827-832
Objectives Improving immune status of people living with HIV through antiretroviral therapy (ART) may also reduce shedding of other viruses in semen. We characterized the seminal fluid virome of men with HIV and tested potential associations between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65368adf669e692433ea658c2ce2c9a6
https://doi.org/10.1097/qad.0000000000002497
https://doi.org/10.1097/qad.0000000000002497
Autor:
David Siegel, Timothy J. Henrich, Keith R. Jerome, Rebecca Hoh, Kristen S. Hobbs, Pavitra Roychoudhury, Mary Carrington, Sulggi A. Lee, Michael P. Busch, Deanna L. Kroetz, Tony Pan, Erica A. Gibson, Christopher D. Pilcher, Eunice Wan, Jeffrey Marin, Cassandra Thanh, Hans-Peter Kiem, Meei-Li Huang, Mars Stone, Peter W. Hunt, Steven G. Deeks, Jeffrey M. Milush, Satish K. Pillai, Frederick Hecht, Maureen Martin, Kevin Haworth
ObjectivePrior genomewide association studies have identified variation in MHC Class I alleles andCCR5Δ32as genetic predictors of viral control, especially in “elite” controllers, individuals who remain virally suppressed in the absence of thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::951d70da395584a5fad12c6d68e4ef35
https://doi.org/10.1101/2021.10.31.466670
https://doi.org/10.1101/2021.10.31.466670
