Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Christopher Cummings"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
The field of biotechnology has produced a wide variety of materials and products which are rapidly entering the commercial marketplace. While many developments promise revolutionary benefits, some of them pose uncertain or largely untested risks and
Externí odkaz:
https://doaj.org/article/224520da29294a2da173f13a5370e269
Autor:
Jerry Skefos, Christopher Cummings, Katelyn Enzer, Jarrod Holiday, Katrina Weed, Ezra Levy, Tarik Yuce, Thomas Kemper, Margaret Bauman
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e81255 (2014)
Neuropathological studies, using a variety of techniques, have reported a decrease in Purkinje cell (PC) density in the cerebellum in autism. We have used a systematic sampling technique that significantly reduces experimenter bias and variance to es
Externí odkaz:
https://doaj.org/article/eec9cf602d1343f786064e28eb9c1e13
Autor:
Yi Zhong, Zheng Wang, Baojin Fu, Fan Pan, Shinichi Yachida, Mousumi Dhara, Emilia Albesiano, Li Li, Yoshiki Naito, Felip Vilardell, Christopher Cummings, Paola Martinelli, Ang Li, Raluca Yonescu, Qingyong Ma, Constance A Griffin, Francisco X Real, Christine A Iacobuzio-Donahue
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22129 (2011)
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease characterized by late diagnosis and treatment resistance. Recurrent genetic alterations in defined genes in association with perturbations of developmental cell signaling pathways hav
Externí odkaz:
https://doaj.org/article/f6e7554200474cf59b9236fd4b796cef
Autor:
Lois Starr, Christopher Cummings
Publikováno v:
American Journal of Medical Genetics Part A. 191:332-337
GTF2IRD1, a gene on chromosome 7 which encodes a transcription factor, is of significant clinical interest due to its heterozygous loss as part of the classical deletion associated with Williams-Beuren syndrome (WBS). However, biallelic variants in G
Autor:
Shriarjun Shastry, WENNING CHU, Eduardo Barbieri, Paul Greback-Clarke, William Smith, Christopher Cummings, Ariann Minzoni, Jenifer Pancorbo, Gary Gilleskie, Kimberly Ritola, Michael Daniele, Stefano Menegatti
Adeno-associated viruses (AAVs) have acquired a central role in modern medicine as delivery agents for gene therapies targeting rare diseases. While new AAVs with improved tissue targeting, potency, and safety are being introduced, their biomanufactu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c0f5dbe3699604a92d5295a79371f52
https://doi.org/10.22541/au.168482798.87003310/v1
https://doi.org/10.22541/au.168482798.87003310/v1
Publikováno v:
Agriculture and Human Values.
Publikováno v:
Transportation Research Record: Journal of the Transportation Research Board. 2677:1012-1026
To ease urban congestion, advanced air mobility (AAM) proposes the use of small aerial vehicles at low altitudes for uses such as package delivery and passenger services. In a developed state, an AAM service is predicted to involve thousands of trips
Autor:
Said M. Sebti, Andrew D. Hamilton, Jose G. Trevino, Jason B. Fleming, Patrick W. Underwood, Andrea Delitto, Michael P. Kim, Ya'an Kang, Francisca Beato, Harshani R. Lawrence, Christopher Cummings, Steven Fletcher, Muhammad Ayaz, Perry Kennedy, Liwei Chen, Hua Yang, Shengyan Xiang, Aslamuzzaman Kazi
Purpose:Mutant KRAS is a major driver of pancreatic oncogenesis and therapy resistance, yet KRAS inhibitors are lacking in the clinic. KRAS requires farnesylation for membrane localization and cancer-causing activity prompting the development of farn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fe9b119d20d64790f763c5df4d19fc
https://doi.org/10.1158/1078-0432.c.6528320.v1
https://doi.org/10.1158/1078-0432.c.6528320.v1
Autor:
Wenning Chu, Shriarjun Shastry, Eduardo Barbieri, Raphael Prodromou, Paul Greback-Clarke, Will Smith, Brandyn Moore, Ryan Kilgore, Christopher Cummings, Jennifer Pancorbo, Gary Gilleskie, Michael A. Daniele, Stefano Menegatti
Adeno-associated viruses (AAVs) are the vector of choice for delivering gene therapies that can cure inherited and acquired diseases. Clinical research on various AAV serotypes significantly increased in recent years alongside regulatory approvals of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94fada79f9909167b77e2b362ce8c96
https://doi.org/10.22541/au.167710254.46384979/v1
https://doi.org/10.22541/au.167710254.46384979/v1
Autor:
Karen Smilowitz, Yuhan Zhou, Divyakant Tahlyan, Hoseb Abkarian, Christopher Cummings, Hani S. Mahmassani
Publikováno v:
Transportation Research Record: Journal of the Transportation Research Board. 2676:192-203
Large-scale planned special events (PSEs) can pose unique transportation and logistics challenges. Data collection and simulation are important tools to address these challenges, although they are often difficult because of event size and complexity.