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pro vyhledávání: '"Christopher Converse Wells"'
Autor:
Andrew Lake, Christopher Converse Wells, Bijan Etemad-Gilbertson, Austin Dulak, Das Sonia, Vito J. Palombella, Warren Michael, Ernest S. Smith, Pamela M. Holland, Maria Scrivens
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background T regulatory cells (Tregs) are potent suppressors of immune activation in the periphery and tumor microenvironment (TME). Tumor-infiltrating Tregs have also been associated with resistance to cancer therapies. Loss of peripheral Tregs can
Autor:
Devapregasan Moodley, Christopher Converse Wells, Kerry White, Matthew Rausch, Jing Hua, Katherine H. Walsh, Pamela M. Holland, Chappel Scott, Christine Miller, Jonathan Hill, Benjamin H. Lee
Publikováno v:
Cancer Research. 79:558-558
MERTK, a member of the TAM (TYRO3, AXL, MERTK) family of receptor tyrosine kinases, is a pleiotropic immune modulator that controls efferocytosis. Engagement of MERTK with its ligand GAS6, found anchored to phosphatidylserine exposed on the outer mem