Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christopher Clowes"'
Autor:
Heba Shawer, Esther Aiyelaagbe, Christopher Clowes, Samantha C Lean, Yinhui Lu, Karl E Kadler, Alan Kerby, Mark R Dilworth, Kathryn E Hentges, Alexander E P Heazell
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233007 (2020)
BackgroundIn humans, stillbirth describes the death of a fetus before birth after 28 weeks gestation, and accounts for approximately 2.6 million deaths worldwide annually. In high-income countries, up to half of stillbirths have an unknown cause and
Externí odkaz:
https://doaj.org/article/bde0bfa951944a7fbce9950e6e922abc
Autor:
Liam A Ridge, Karen Mitchell, Ali Al-Anbaki, Wasay Mohiuddin Shaikh Qureshi, Louise A Stephen, Gennadiy Tenin, Yinhui Lu, Irina-Elena Lupu, Christopher Clowes, Abigail Robertson, Emma Barnes, Jayne A Wright, Bernard Keavney, Elisabeth Ehler, Simon C Lovell, Karl E Kadler, Kathryn E Hentges
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007068 (2017)
The coronary vasculature is an essential vessel network providing the blood supply to the heart. Disruptions in coronary blood flow contribute to cardiac disease, a major cause of premature death worldwide. The generation of treatments for cardiovasc
Externí odkaz:
https://doaj.org/article/4a841ebc5e44469a893feb2ef3277b47
Autor:
Gennadiy Tenin, Christopher Clowes, Kathryn Wolton, Eliska Krejci, Jayne A Wright, Simon C Lovell, David Sedmera, Kathryn E Hentges
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107041 (2014)
The heart is the first organ required to function during embryonic development and is absolutely necessary for embryo survival. Cardiac activity is dependent on both the sinoatrial node (SAN), which is the pacemaker of heart's electrical activity, an
Externí odkaz:
https://doaj.org/article/dd9c4cef52324dfc9d60cfaee582933a
Autor:
Alan Kerby, Christopher Clowes, Yinhui Lu, Samantha C. Lean, Karl E. Kadler, Kathryn E. Hentges, Alexander E. P. Heazell, Mark Dilworth, Esther Aiyelaagbe, Heba Shawer
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233007 (2020)
PLoS ONE
PLoS ONE
BackgroundIn humans, stillbirth describes the death of a fetus before birth after 28 weeks gestation, and accounts for approximately 2.6 million deaths worldwide annually. In high-income countries, up to half of stillbirths have an unknown cause and
Autor:
Kayleigh L. Banyard, Paolo Matteuci, Matthew J. Hardman, Christopher Clowes, Kimberly A. Mace, Holly N. Wilkinson
Publikováno v:
The Journal of investigative dermatology. 139(5)
Cellular senescence can be broadly defined as a stable, but essentially irreversible, loss of proliferative capacity. Historically, senescence has been described as a negative outcome of advanced cellular age. It is now clear, however, that senescenc
Autor:
Emma Barnes, Michael G.S. Boylan, Jayne Wright, Liam A. Ridge, Kathryn E. Hentges, Christopher Clowes
Publikováno v:
genesis. 52:713-737
Genes required for an organism to develop to maturity (for which no other gene can compensate) are considered essential. The continuing functional annotation of the mouse genome has enabled the identification of many essential genes required for spec
Publikováno v:
Developmental Biology. 342(2):146-156
During development, the mammalian embryo must integrate signals to control growth and proliferation. A failure in the ability to respond to mitogenic stimuli can cause embryonic growth restriction. We have identified a mouse mutant, l11Jus15, from a
Autor:
Raymond P. Boot-Handford, M. Helen Rajpar, Christopher Clowes, Michael D. Briggs, David J. Thornton, Peter A. Bell, Leo A. H. Zeeff, Seema Nundlall, Benjamin Gardner
Publikováno v:
Cell Stress & Chaperones
Multiple epiphyseal dysplasia (MED) can result from mutations in matrilin-3, a structural protein of the cartilage extracellular matrix. We have previously shown that in a mouse model of MED the tibia growth plates were normal at birth but developed
Autor:
Jill Dixon, Christopher Clowes, Pamela M. Willan, Caroline F. Drew, Chunyan Mou, Helen A. Thomason, W. Edwin Harris, Michael J. Dixon, Denis J. Headon
Publikováno v:
Mou, C, Thomason, H A, Willan, P M, Clowes, C, Harris, W E, Drew, C F, Dixon, J, Dixon, M J & Headon, D J 2008, ' Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form ', Human Mutation, vol. 29, no. 12, pp. 1405-11 . https://doi.org/10.1002/humu.20795
Hair morphology differs dramatically between human populations: people of East Asian ancestry typically have a coarse hair texture, with individual fibers being straight, of large diameter, and cylindrical when compared to hair of European or African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657dfed56a71e051e6e4152fb4edee43
https://www.pure.ed.ac.uk/ws/files/8264337/Mou_et_al_EDAR_and_Asian_Hair_2008_supplementary_material.pdf
https://www.pure.ed.ac.uk/ws/files/8264337/Mou_et_al_EDAR_and_Asian_Hair_2008_supplementary_material.pdf