Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher Cardi"'
Autor:
Nylla Shanthly, Mathew L. Thakur, Christopher Cardi, Kaijun Zhang, Eric Wickstrom, Xiaobing Tian, Mohan R. Aruva
Publikováno v:
Journal of Nuclear Medicine. 48:1699-1707
Treatment of breast cancer is hampered by a large unmet need for rapid, sensitive, specific staging and stratification of palpable and nonpalpable abnormalities. Mammography and physical examination miss many early breast cancers, yet detect many ben
Autor:
Eric Wickstrom, Christopher Cardi, Mohan R. Aruva, Mathew L. Thakur, Armin W. Opitz, Kaijun Zhang, A. Chakrabarti, Norman J. Wagner
Publikováno v:
Cancer Biology & Therapy. 6:948-956
There is a compelling need to image pancreas cancer at an early stage. Human pancreas cancer cells display elevated levels of KRAS protein due to high copy numbers of KRAS mRNA, and elevated levels of insulin-like growth factor 1 receptor (IGF1R) due
Autor:
Christopher A. Barker, Christopher Cardi, Rex A. Iozzo, Gregory J. Bix, Remedios Castello, Michelle Weech, Michelle Burrows, Mathew L. Thakur, Renato V. Iozzo, Kevin Camphausen, Jason J. Zoeller
Publikováno v:
JNCI: Journal of the National Cancer Institute. 98:1634-1646
Background: The antiangiogenic approach to controlling cancer requires a better understanding of angiogenesis and the discovery of new compounds that modulate this key biological process. Here we investigated the role of endorepellin, an angiostatic
Autor:
Harshali Bal, D. Thomas, Paul D. Acton, Philipp T. Meyer, Christopher Cardi, Valentina Circiumaru
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 33:948-954
Arterial input function (AIF) measurement for quantification of small animal PET studies is technically challenging and limited by the small blood volume of small laboratory animals. The present study investigated the use of a standard arterial input
Autor:
Nariman V. Amirkhanov, A. Chakrabarti, Boby Mathew, Wenyi Qin, Christopher Cardi, Mohan R. Aruva, Mathew L. Thakur, Edward R. Sauter, Kaijun Zhang, Eric Wickstrom, Xiaobing Tian
Publikováno v:
Annals of the New York Academy of Sciences. 1059:106-144
In 2005, breast cancer will kill approximately 40,410 women in the U.S., and pancreatic cancer will kill approximately 31,800 men and women in the U.S. Clinical examination and mammography, the currently accepted breast cancer screening methods, miss
Autor:
Norman J. Wagner, Christopher Cardi, Armin W. Opitz, Song Lai, Nariman V. Amirkhanov, Ivan E. Dimitrov, John Lackey, Kaijun Zhang, Mathew L. Thakur, Eric Wickstrom
Publikováno v:
Biopolymers. 89(12)
We hypothesized that chelating Gd(III) to 1,4,7-tris(carboxymethylaza)cyclododecane-10-azaacetylamide (DO3A) on peptide nucleic acid (PNA) hybridization probes would provide a magnetic resonance genetic imaging agent capable of hybridization to a spe
Autor:
Christopher Kim, Mathew L. Thakur, Chirag A. Patel, Kaijun Zhang, Christopher Cardi, Mohan R. Aruva, Satish Rattan, Nylla Shanthly, Eric Wickstrom, Peter McCue
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 49(1)
Among U.S. men, prostate cancer (PC) accounts for 29% of all newly diagnosed cancers. A reliable scintigraphic agent to image PC and its metastatic or recurrent lesions and to determine the effectiveness of its treatment will contribute to the manage
Autor:
Kaijun Zhang, Christopher Cardi, Mohan R. Aruva, Mathew L. Thakur, Gregory Cesarone, Nylla Shanthly, Satish Rattan, Eric Wickstrom, Chirag A. Patel
Publikováno v:
Regulatory peptides. 144(1-3)
Vasoactive intestinal peptide and pituitary adenylate cyclase activating peptide have high affinity for VPAC1, VPAC2 and PAC1 receptors overexpressed on human cancer cells. Four potent analogues of these peptides, TP3939, TP3982, TP4200 and TP3805 we
Autor:
Christopher Cardi, Eric Wickstrom, Mohan R. Aruva, Song Lai, Mathew L. Thakur, Kaijun Zhang, A. Chakrabarti, Nariman V. Amirkhanov, Xiaobing Tian
Publikováno v:
Biochemical Society transactions. 35(Pt 1)
Early external detection of cancer gene activity might enable early treatment of cancer and might reduce cancer mortality. We hypothesized that oncogene mRNA overexpressed at thousands of copies per malignant cell in a zone of transformed cells could
Publikováno v:
2007 IEEE Nuclear Science Symposium Conference Record.
In previous work we demonstrated the feasibility to conduct SPECT imaging using a multi-pinhole collimator insert in a small animal PET scanner. A simplified analytical simulation method was used, modeling mainly geometric attributes, to optimize the