Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christopher C. Massin"'
Autor:
Marcian E. Van Dort, Christopher C. Massin, Suresh G. Mislankar, Gary D. Hutchins, David L. Gildersleeve, Markus Schwaiger, Philip S. Sherman, Jill Rothley, Karen C. Rosenspire, Helen Lee, Donald M. Wieland
Publikováno v:
Journal of Medicinal Chemistry. 33:956-964
The false neurotransmitter metaraminol labeled with fluorine-18 has been used to noninvasively assess regional adrenergic nerve density in the canine heart. Intravenous administration of 6-({sup 18}F)fluorometaraminol (FMR) results in high, selective
Autor:
David L. Gildersleeve, Suresh G. Mislankar, Donald M. Wieland, Steven A. Toorongian, G. Keith Mulholland, Christopher C. Massin
Publikováno v:
Journal of Medicinal Chemistry. 31:362-366
The false neurotransmitter metaraminol has been 18F labeled and evaluated as a possible heart imaging agent on the basis of its selective accumulation in adrenergic nerves. Reaction of 6-(acetoxymercurio)-N-t-BOC-metaraminol with acetyl hypofluorite
Autor:
David L. Gildersleeve, Christopher C. Massin, Donald M. Wieland, Karen C. Rosenspire, Suresh G. Mislankar
Publikováno v:
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 16(7)
Studies were performed to determine whether [18F]6-fluorometaraminol (18F-FMR), a new neuronal heart radiopharmaceutical, is metabolized in vivo and if the metabolites are taken up in heart. Rat, dog, baboon and guinea pig were injected with 18F-FMR