Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher C. Joneckis"'
Autor:
Sheritha P. Lee, Michelle L. Cunningham, Patrick C. Hines, Christopher C. Joneckis, Eugene P. Orringer, Leslie V. Parise
Publikováno v:
Blood. 92:2951-2958
Sickle red blood cell (RBC) adhesion to the endothelium and to exposed, underlying subendothelial proteins is believed to contribute to vascular occlusion in sickle cell disease. Laminin, a major component of the subendothelium, supports significant
Autor:
Leslie V. Parise, Michelle L. Cunningham, Christopher C. Joneckis, David D. Shock, Eugene P. Orringer
Publikováno v:
Blood. 87:4862-4870
The abnormal adherence of red blood cells (RBC to the blood vessel wall is believed to contribute to the vascular occlusion observed in patients with sickle call anemia. The cell adhesion receptors GPIV (CD36) and integrin alpha 4 beta 1 (CD49d/CD29)
Autor:
Elizabeth A. Wayner, Rhonda L. Ackley, Eugene P. Orringer, Leslie V. Parise, Christopher C. Joneckis
Publikováno v:
Blood. 82:3548-3555
The abnormal adherence of red blood cells, especially circulating reticulocytes (erythrocyte precursors), to the endothelium is believed to contribute to vascular occlusion observed in patients with sickle cell disease. Although several plasma protei
Publikováno v:
Blood. 81:2827-2843
Publikováno v:
Cytometry. 10:185-191
To improve the ability of flow cytometry to detect multidrug-resistant cells, we studied the extent to which cell volume heterogeneity accounts for the variance of intracellular daunorubicin (DNR) content. For P388 murine or HL-60 human leukemia cell
Publikováno v:
Blood. 68:83-88
The effects of verapamil on the intracellular pharmacokinetics of daunorubicin (DNR) in blast cells from the bone marrows of patients with acute nonlymphocytic leukemia (ANLL) were studied to determine whether verapamil was capable of enhancing intra
Autor:
Charles A. Schiffer, Douglas D. Ross, Christopher C. Joneckis, Steven A. Akman, Bruce W. Thompson
Publikováno v:
Blood. 68:76-82
The dose-response relationship between extracellular concentration of cytosine arabinoside (ara-C) and intracellular formation of the putative active metabolites of ara-C [ara-C incorporation into DNA and intracellular pools of ara-C in triphosphate
Publikováno v:
Biochemical Pharmacology. 33:1059-1063
We studied the ability of 2'-deoxyguanosine (dGuo) to influence 1-beta-D-arabinofuranosylcytosine (ara-C) inhibition of soft agar cloning of the cultured human leukemia cell line K562. Ara-C alone inhibited cloning in concentrations of greater than 1
Autor:
Bruce W. Thompson, Douglas D. Ross, Christopher C. Joneckis, Joseph R. Testa, Jose V. Ordonez
Publikováno v:
Cytometry. 9(4)
To investigate the spontaneous frequency of occurrence of stable multidrug-resistant cells in a population of drug-sensitive cells, we exposed drug sensitive P388/S cells to daunorubicin (dnr) for 1 h, then used fluorescence-activated cell sorting ba
Autor:
Woodcock J; Food and Drug Administration, 5600 Fishers Lane, Rockville, Maryland 20857, USA. janet.woodcock@fda.hhs.gov, Griffin J, Behrman R, Cherney B, Crescenzi T, Fraser B, Hixon D, Joneckis C, Kozlowski S, Rosenberg A, Schrager L, Shacter E, Temple R, Webber K, Winkle H
Publikováno v:
Nature reviews. Drug discovery [Nat Rev Drug Discov] 2007 Jun; Vol. 6 (6), pp. 437-42.