Pharmacokinetic and Pharmacodynamic Analysis of Ceftazidime/Avibactam in Critically Ill Patients

Autor: Joseph L. Kuti, Curtis L. Smith, Christopher C Cooper, Gary E. Stein, Amy Scharmen, Daniel H. Havlichek, Subhashis Mitra, James M Kidd, David P. Nicolau

Publikováno v: Surgical Infections. 20:55-61

The pharmacokinetics, especially the volume of distribution (Vd), of ß-lactam antibiotics can be altered in critically ill patients. This can lead to decreased serum concentrations and a reduction in clinical cures. Ceftazidime/avibactam (CZA) is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bc28408f578ee87300590271d63180
https://doi.org/10.1089/sur.2018.141

Long-Acting Lipoglycopeptides for the Treatment of Bone and Joint Infections

Autor: Ahmed Abubaker, Subhashis Mitra, Christopher C Cooper, Daniel H. Havlichek, Gary E. Stein

Publikováno v: Surgical infections. 22(8)

Background: The long-acting lipoglycopeptides dalbavancin and oritavancin possess excellent microbiologic activity against gram-positive bacteria and provide prolonged tissue exposure at sites of infection. Moreover, these antibiotics are well tolera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80a1a9239dfd81af05084e4d1dba339
https://pubmed.ncbi.nlm.nih.gov/33835882

2075. The Hypothetical Impact of Accelerate Pheno on Time to Appropriate Therapy (TTAT) and Time to Optimal Therapy (TTOT) in an Institution with an Established Antimicrobial Stewardship Program and Rapid Genotypic Organism/Resistance Marker Identification

Autor: Christopher C Cooper, Kathryn Deeds, Jason M. Pogue, Jinit Patel, Oryan Henig, Zara Hussain, Noman Hussain, Paul Lephart, Keith S Kaye, Umar Hayat, Hossein Salimnia

Publikováno v: Open Forum Infectious Diseases

Background Rapid organism identification (ID) and antimicrobial susceptibility testing (AST) can improve time to adequate therapy (TTAT) and optimal (TTOT). The Accelerate Pheno™ system (ACC) can provide ID and AST results within 7 hours. The objec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f87eb0611085a354c4c58acb24bf75e
https://doi.org/10.1093/ofid/ofy210.1731

Multicast communication on the Unison network

Autor: David H. Shrimpton, Christopher C. Cooper

Publikováno v: Computer Communications. 13:460-468

A multicast access architecture for a multiservice network is described. The system is based on the use of a distributed set of multicast agents which are responsible for regulating access to the service and for effecting the distribution of data. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b39c376bff121763a18aab29b83bd01c
https://doi.org/10.1016/0140-3664(90)90129-5

Metabolic Aging as an Increased Risk for Chronic Obstructive Pulmonary Disease.

Autor: Guo CJ; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Godbole S; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Labaki WW; Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Pratte KA; Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, CO 80206, USA., Curtis JL; Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Medical Service, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA., Paine R; Division of Respiratory, Critical Care and Occupational Medicine, University of Utah, Salt Lake City, UT 84132, USA., Hoffman E; Department of Radiology, University of Iowa, Iowa City, IA 52242, USA., Han M; Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, CO 80206, USA., Ohar J; Section of Pulmonary, Critical Care, Allergy and Immunologic Diseases, Department of Internal Medicine, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC 27101, USA., Cooper C; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA., Kechris KJ; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Bowler RP; Genomic Medicine Institute, Cleveland Clinic, Cleveland, OH 44106, USA.

Publikováno v: Metabolites [Metabolites] 2024 Nov 21; Vol. 14 (12). Date of Electronic Publication: 2024 Nov 21.