Skeletal muscle hypertrophy and attenuation of cardio-metabolic risk factors (SHARC) using functional electrical stimulation-lower extremity cycling in persons with spinal cord injury: study protocol for a randomized clinical trial

Autor: Ashraf S. Gorgey, Refka E. Khalil, John C. Davis, William Carter, Ranjodh Gill, Jeannie Rivers, Rehan Khan, Lance L. Goetz, Teodoro Castillo, Timothy Lavis, Adam P. Sima, Edward J. Lesnefsky, Christopher C. Cardozo, Robert A. Adler

Publikováno v: Trials, Vol 20, Iss 1, Pp 1-14 (2019)

Abstract Background Persons with spinal cord injury (SCI) are at heightened risks of developing unfavorable cardiometabolic consequences due to physical inactivity. Functional electrical stimulation (FES) and surface neuromuscular electrical stimulat

Externí odkaz: https://doaj.org/article/daa5c1b5d61d4fddbc6fcd3d8e15e8f3

Sclerostin Antibody Preserves the Morphology and Structure of Osteocytes and Blocks the Severe Skeletal Deterioration After Motor-Complete Spinal Cord Injury in Rats

Autor: Yinshi Ren, Yiwen Qin, Shijia Zheng, Jiliang Li, William A. Bauman, Xiaodong Li, Jie Sun, Weiping Qin, Lauren Harlow, Hua Zhu Ke, Christopher C Cardozo, Yingjie Wu, Jian Q. Feng, Thomas P. Brown, Yuanzhen Peng

Publikováno v: Journal of Bone and Mineral Research. 30:1994-2004

Unloading, neural lesions, and hormonal disorders after acute motor-complete spinal cord injury (SCI) cause one of the most severe forms of bone loss, a condition that has been refractory to available interventions tested to date. Thus, these feature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14fbbaff0032660176458c49ed35194a
https://doi.org/10.1002/jbmr.2549

Advanced Methodology for Rapid Isolation of Single Myofibers from Flexor Digitorum Brevis Muscle.

Autor: Awad K; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Moore L; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Huang J; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Gomez L; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Brotto L; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Varanasi V; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Cardozo C; National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters Department of Veterans Affairs Medical Center, New York, New York, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Weisleder N; Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, USA., Pan Z; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Zhou J; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA., Bonewald L; Indiana Center for Musculoskeletal Health, Indiana University Medical School, Indianapolis, Indiana, USA., Brotto M; Bone Muscle Research Center, College of Nursing and Health Innovations, Department of Graduate Nursing, University of Texas at Arlington, Arlington, Texas, USA.

Publikováno v: Tissue engineering. Part C, Methods [Tissue Eng Part C Methods] 2023 Aug; Vol. 29 (8), pp. 349-360. Date of Electronic Publication: 2023 May 24.

Myostatin inhibits insulin-like growth factor 1-dependent citrate secretion and osteogenesis via nicotinamide adenine dinucleotide phosphate oxidase-4 in a mouse mesenchymal stem cell line.

Autor: Liu XH; National Center for the Medical Consequences of Spinal Cord Injury, James J. Peter VA Medical Center, Bronx, New York, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Pan JP; National Center for the Medical Consequences of Spinal Cord Injury, James J. Peter VA Medical Center, Bronx, New York, USA., Bauman WA; National Center for the Medical Consequences of Spinal Cord Injury, James J. Peter VA Medical Center, Bronx, New York, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Medical Service, James J. Peter VA Medical Center, Bronx, New York, USA.; Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Cardozo C; National Center for the Medical Consequences of Spinal Cord Injury, James J. Peter VA Medical Center, Bronx, New York, USA.; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Medical Service, James J. Peter VA Medical Center, Bronx, New York, USA.; Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Bone Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Publikováno v: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2022 Nov; Vol. 1517 (1), pp. 203-212. Date of Electronic Publication: 2022 Sep 07.

Electrical stimulation of hindlimb skeletal muscle has beneficial effects on sublesional bone in a rat model of spinal cord injury.

Autor: Zhao W; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Peng Y; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA., Hu Y; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Guo XE; Department of Biomedical Engineering, Columbia University, New York, NY, USA., Li J; Indiana University Purdue University Indianapolis, Indianapolis, IN, USA., Cao J; United States Department of Agriculture Agricultural Research Service Human Nutrition Research Center, Grand Forks, ND, USA., Pan J; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA., Feng JQ; Baylor College of Dentistry, TX A&M, Dallas, TX, USA., Cardozo C; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Jarvis J; School of Sport and Exercise Sciences, Liverpool John Moores University, Liverpool L3 3AF, United Kingdom., Bauman WA; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Qin W; National Center for the Medical Consequences of SCI, James J. Peters VA Medical Center, Bronx, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: weiping.qin@mssm.edu.

Publikováno v: Bone [Bone] 2021 Mar; Vol. 144, pp. 115825. Date of Electronic Publication: 2020 Dec 19.