Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels

Autor: Enateri V. Alakpa, Vineetha Jayawarna, Karl E. V. Burgess, Christopher C. West, Bruno Péault, Rein V. Ulijn, Matthew J. Dalby

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract Differentiation of stem cells to chondrocytes in vitro usually results in a heterogeneous phenotype. This is evident in the often detected over expression of type X collagen which, in hyaline cartilage structure is not characteristic of the

Externí odkaz: https://doaj.org/article/95134f7e2eff4a20a241be0b0bcaf930

Characterization of Human Pericyte Phenotype by Immunohistochemistry

Autor: Christopher C, West, Nusrat S, Khan, Mihaela, Crisan

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2235

Pericytes are found in all vascularized organs and are defined anatomically as perivascular cells that closely surround endothelial cells in capillaries and microvessels and are embedded within the same basement membrane. They have been shown to have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8645b53b13e83e1c189e53efd0e1ed52
https://pubmed.ncbi.nlm.nih.gov/33576969

Assessment of Pericyte Phenotype by Flow Cytometry

Autor: Fiona Rossi, Nusrat Khan, Mihaela Crisan, Christopher C. West

Publikováno v: Pericytes ISBN: 9781071610558

Pericytes are mural cells closely associated with endothelial cells in capillaries and microvessels. They are precursors of mesenchymal stem/stromal cells that have historically been retrospectively characterized in culture. We established a protocol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56c6a8a6cc7676ce5c6d24bd23cbafb0
https://doi.org/10.1007/978-1-0716-1056-5_3

Characterization of Human Pericyte Phenotype by Immunohistochemistry

Autor: Christopher C. West, Mihaela Crisan, Nusrat Khan

Publikováno v: Pericytes ISBN: 9781071610558

Pericytes are found in all vascularized organs and are defined anatomically as perivascular cells that closely surround endothelial cells in capillaries and microvessels and are embedded within the same basement membrane. They have been shown to have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80d49749f3ec54b67ce5597e38cf3893
https://doi.org/10.1007/978-1-0716-1056-5_4

Deciphering Mesenchymal Drivers of Human Dupuytren’s Disease at Single-Cell Level

Autor: Ahsan R. Akram, Jordan R. Portman, Prakash Ramachandran, Laura J. Kitto, Li Yenn Yong, Neil C. Henderson, Dyana Markose, Beth E. P. Henderson, John R. Wilson-Kanamori, Dominique Davidson, Sadaf Sohrabi, Mariana Beltran, Christopher C. West, Ross Dobie

Publikováno v: Dobie, R, West, C C, Henderson, B E, Wilson-Kanamori, J R, Markose, D, Kitto, L J, Portman, J R, Beltran, M, Sohrabi, S, Akram, A R, Ramachandran, P, Yong, L Y, Davidson, D & Henderson, N C 2022, ' Deciphering mesenchymal drivers of human Dupuytren's disease at single-cell level ', Journal of Investigative Dermatology, vol. 142, no. 1, pp. 114-123.e8 . https://doi.org/10.1016/j.jid.2021.05.030

Dupuytren's disease (DD) is a common, progressive fibroproliferative disease affecting the palmar fascia of the hands, causing fingers to irreversibly flex towards the palm with significant loss of function. Surgical treatments are limited, therefore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a3ce9f9c27e568af826cbf5c9f1d83
https://doi.org/10.1016/j.jid.2021.05.030