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pro vyhledávání: '"Christopher Batram"'
Autor:
Andreas J. W. Hartel, Marius Glogger, Nicola G. Jones, Wasim Abuillan, Christopher Batram, Anne Hermann, Susanne F. Fenz, Motomu Tanaka, Markus Engstler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
How molecular crowding affects membrane protein diffusion and function is not known. Here the authors measure diffusion of variant surface glycoprotein on trypanosomes and discover a molecular crowding threshold that limits diffusion, and find that N
Externí odkaz:
https://doaj.org/article/831b8d33c8d54ce4a633cf358d818285
Autor:
Henriette Zimmermann, Ines Subota, Christopher Batram, Susanne Kramer, Christian J Janzen, Nicola G Jones, Markus Engstler
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006324 (2017)
For persistent infections of the mammalian host, African trypanosomes limit their population size by quorum sensing of the parasite-excreted stumpy induction factor (SIF), which induces development to the tsetse-infective stumpy stage. We found that
Externí odkaz:
https://doaj.org/article/cec026f09778468aa81adc6fb0297d52
Publikováno v:
eLife, Vol 3 (2014)
We have discovered a new mechanism of monoallelic gene expression that links antigenic variation, cell cycle, and development in the model parasite Trypanosoma brucei. African trypanosomes possess hundreds of variant surface glycoprotein (VSG) genes,
Externí odkaz:
https://doaj.org/article/511b17a7f3ad40bb8bfb3978722fd706
The cell surface of bloodstream form African trypanosomes is covered by a dense coat of immunogenic variant surface glycoproteins (VSGs). By continuously changing the expressed VSG antigen, the parasites can survive the host’s immune response. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ea8096ee94d0c03714384f24b62c78
https://doi.org/10.1101/2021.05.05.442555
https://doi.org/10.1101/2021.05.05.442555
Autor:
Marius Glogger, Motomu Tanaka, Anne Hermann, Andreas Hartel, Markus Engstler, Christopher Batram, Susanne F. Fenz, Nicola G. Jones, Wasim Abuillan
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
The protein density in biological membranes can be extraordinarily high, but the impact of molecular crowding on the diffusion of membrane proteins has not been studied systematically in a natural system. The diversity of the membrane proteome of mos