Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Christopher B. Benton"'
Autor:
Christopher B. Benton, Ding He, Karen Todoroff, Marie V. Coignet, Ying Luan, Jason C. Wong, Kathryn N. Kurtzman, Ira Zackon
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 3643-3656 (2024)
To help determine the unmet need for improved diagnostic tools to evaluate patients with nonspecific signs and/or symptoms (NSSS) and suspicion of cancer, we examined patient characteristics, diagnostic journey, and cancer incidence of patients with
Externí odkaz:
https://doaj.org/article/8c7e449234f849c0b3f65166880ffa6b
Autor:
Naval Daver, Allyson Price, Christopher B. Benton, Keyur Patel, Weiguo Zhang, Marina Konopleva, Naveen Pemmaraju, Koichi Takahashi, Michael Andreeff, Gautam Borthakur
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The prognostics implications of patients with acute myeloid leukemia harboring non-canonical FLT3 is unknown. The use of tyrosine kinase inhibitors in this patient population has not been previously reported. We report successful targeted therapy aga
Externí odkaz:
https://doaj.org/article/e9d0483f1b994cf998300389992288c5
Autor:
Kamal Chamoun, Sanam Loghavi, Naveen Pemmaraju, Marina Konopleva, Michael Kroll, Madeleine Nguyen-Cao, Marisa Hornbaker, Courtney D. DiNardo, Tapan Kadia, Jeffrey Jorgensen, Michael Andreeff, Shimin Hu, Christopher B. Benton
Publikováno v:
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-5 (2018)
Abstract Background Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy characterized by neoplastic cells that are positive for CD123, CD4, BDCA2, and TCL1 and aberrant expression of CD56. Historically
Externí odkaz:
https://doaj.org/article/d8e1378666f442c4aef4643e1d9f1fd5
Autor:
Prajwal Boddu, Hagop M. Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Srdan Verstovsek, Elias Jabbour, Gautam Borthakur, Marina Konopleva, Kapil N. Bhalla, Naval Daver, Courtney D. DiNardo, Christopher B. Benton, Koichi Takahashi, Zeev Estrov, Sherry R. Pierce, Michael Andreeff, Jorge E. Cortes, Tapan M. Kadia
Publikováno v:
Blood Advances, Vol 1, Iss 17, Pp 1312-1323 (2017)
Abstract: Secondary acute myeloid leukemia (s-AML) includes therapy-related AML and AML evolving from antecedent hematological disorder (AHD). s-AML arising after treating AHD likely represents a prognostically distinct, high-risk disease category. I
Externí odkaz:
https://doaj.org/article/fb67d5abf34d43608bfe5e998d063e71
Autor:
Carlos E. Bueso-Ramos, Marisa J.L. Aitken, Feng Wang, Nicholas J. Short, Christopher B. Benton, Koichi Takahashi, Jianhua Zhang, Shelley M. Herbrich
Publikováno v:
American Journal of Hematology. 95:1117-1120
Autor:
Tapan M. Kadia, Farhad Ravandi, Rita Assi, Feng Wang, Sherry Pierce, Prithviraj Bose, Guillermo Garcia-Manero, Michael Andreeff, Hagop M. Kantarjian, Jorge E. Cortes, Prajwal Boddu, Srdan Verstovsek, Christopher B. Benton, Courtney D. DiNardo, Naveen Pemmaraju, Keyur P. Patel, Marina Konopleva, Devendra Kc
Publikováno v:
Cancer. 125:1855-1866
BACKGROUND Canonical Janus kinase 2 (JAK2) V617F and exon 12 mutations in myeloid neoplasms are well described. There are limited reports of other JAK2 variants of potential clinical relevance. This study was designed to survey JAK2 variants in patie
Autor:
Abhishek Maiti, Farhad Ravandi, Tapan M. Kadia, Elias Jabbour, Steven M. Kornblau, Hagop M. Kantarjian, Sanam Loghavi, Guillermo Garcia-Manero, Xuelin Huang, Jorge E. Cortes, Nicholas J. Short, Wei Qiao, Marina Konopleva, Rashmi Kanagal-Shamanna, Maro Ohanian, Courtney D. DiNardo, Mary Ann Richie, Naveen Pemmaraju, Naval Daver, Gautam Borthakur, Sherry Pierce, Yesid Alvarado, Christopher B. Benton, Nitin Jain, Yvonne Gasior, Zeev Estrov, Prithviraj Bose
Publikováno v:
The Lancet Haematology. 6:e29-e37
Summary Background Hypomethylating agents, such as decitabine, are the standard of care for older patients with newly diagnosed acute myeloid leukaemia. Single-arm studies have suggested that a 10-day schedule of decitabine cycles leads to better out
Autor:
Margarida A. Santos, Nitin Jain, Kelly S. Chien, Abhishek Maiti, Monica Kwari, Sherry Pierce, Jose A. Rodriguez, Ayalew Tefferi, Aref Al-Kali, Marisa J Hornbaker, Animesh Pardanani, Guillermo Garcia-Manero, Darci Zblewski, Sara Martinez, Elias Jabbour, Christopher B. Benton, Naval Daver, Yesid Alvarado, Farhad Ravandi, William J. Hogan, Hagop M. Kantarjian, Mariano Siguero
Publikováno v:
Hematological Oncology. 37:96-102
Background: Trabectedin is an FDA-approved DNA minor groove binder (MGB) that has activity against translocation-associated sarcomas. Lurbinectedin is a next-generation MGB with pre-clinical activity against myeloid leukemia cells. A dose-finding pha
Autor:
Anthony M. Hunter, Farhad Ravandi, Keyur P. Patel, Kim Anh Do, Elias Jabbour, Guillermo Garcia-Manero, Nicholas J. Short, Mark J. Routbort, Panagiotis Katsonis, Rami S. Komrokji, Hagop M. Kantarjian, Christopher B. Benton, Yue Wei, Koji Sasaki, Tapan M. Kadia, Caleb A. Class, Rajyalakshmi Luthra, Carlos E. Bueso-Ramos, Olivier Lichtarge, Guillermo Montalban-Bravo, Irene Ganan-Gomez, Gautam Borthakur, L. Jeffrey Medeiros, Joseph D. Khoury, Najla Al Ali, David A. Sallman, Naval Daver, Kelly A. Soltysiak, Rashmi Kanagal-Shamanna, Michael Andreeff, Kelly S. Chien
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 11, Iss 3, Pp 1-5 (2021)
Blood Cancer Journal, Vol 11, Iss 3, Pp 1-5 (2021)
Two cases of possible familial chronic myeloid leukemia in a family with extensive history of cancer
Autor:
Musa Yilmaz, Ghayas C. Issa, Marisa J.L. Aitken, Koji Sasaki, Nicholas J. Short, Christopher B. Benton
Publikováno v:
Acta Haematol
Chronic myeloid leukemia (CML) is defined by the presence of an oncogenic fusion protein caused by a reciprocal translocation between chromosomes 9q and 22q. While our molecular understanding of CML pathogenesis has revolutionized drug development fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e460e2649b1913cf7b494b2e3439b8
https://europepmc.org/articles/PMC8448803/
https://europepmc.org/articles/PMC8448803/