Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christopher B Guest"'
Autor:
Christopher B Guest, Eric L Deszo, Matthew E Hartman, Jason M York, Keith W Kelley, Gregory G Freund
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1606 (2008)
Macrophages are capable of assuming numerous phenotypes in order to adapt to endogenous and exogenous challenges but many of the factors that regulate this process are still unknown. We report that Ca(2+)/calmodulin-dependent kinase kinase alpha (CaM
Externí odkaz:
https://doaj.org/article/5ed74206df734e87b0b4d31a68fd22d4
Autor:
Christopher B Guest, Matthew E Hartman, Jason C O'Connor, Kenneth S Chakour, Ali A Sovari, Gregory G Freund
Publikováno v:
PLoS ONE, Vol 2, Iss 6, p e511 (2007)
Type 2 diabetes (T2D) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and macrophage cholesteryl ester accumulation. When diabetic (db/
Externí odkaz:
https://doaj.org/article/3850c5e0fc0142c48ef03eaa8dd687db
Autor:
Gregory G. Freund, Uzma Ahmad, Jason M. York, Jonathan W. Martin, Min Jung Park, Meredith B. Barnes, Christopher B. Guest
Publikováno v:
Psychoneuroendocrinology. 33:1411-1418
Summary Objective Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion and social withdrawal. While these clinical symptoms are well characterized, the mechanism of their cause is not understood. Here we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9c64435538eb36220d3f2f1eb113e1
https://doi.org/10.1016/j.psyneuen.2008.08.005
https://doi.org/10.1016/j.psyneuen.2008.08.005
Publikováno v:
The Journal of Immunology. 178:6886-6893
Chronic elevation of proinflammatory markers in type 2 diabetes (T2D) is well defined, but the role of anti-inflammatory cytokines in T2D is less clear. In this study, we report that normal IL-4-dependent elaboration of IL-1 receptor antagonist (IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85d44c028f1b7127232afefbf96e7e6
https://doi.org/10.4049/jimmunol.178.11.6886
https://doi.org/10.4049/jimmunol.178.11.6886
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 13
The incidence of type 2 diabetes (T2D) is rapidly expanding. Some of the more obvious pathologies associated with it include: defective glucose metabolism, obesity, cardiovascular disease and an inability to mount an effective immune response to infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5263aed2f2392b9c5545ee813aeaf71a
https://pubmed.ncbi.nlm.nih.gov/18508580
https://pubmed.ncbi.nlm.nih.gov/18508580
Autor:
Jason M. York, Christopher B. Guest, Keith W. Kelley, Matthew E. Hartman, Gregory G. Freund, Eric L. Deszo
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1606 (2008)
PLoS ONE
PLoS ONE
Macrophages are capable of assuming numerous phenotypes in order to adapt to endogenous and exogenous challenges but many of the factors that regulate this process are still unknown. We report that Ca(2+)/calmodulin-dependent kinase kinase alpha (CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0183fc1a6f62154524c905e0992180
http://europepmc.org/articles/PMC2229650?pdf=render
http://europepmc.org/articles/PMC2229650?pdf=render
Publikováno v:
Psychoneuroimmunology ISBN: 9780120885763
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b044576e96bfae799c71b75a67ed6dd
https://doi.org/10.1016/b978-012088576-3/50054-x
https://doi.org/10.1016/b978-012088576-3/50054-x
Publikováno v:
The FASEB Journal. 20
Type 2 diabetes mellitus (DM) is associated with accelerated atherosclerosis, which accounts for approximately 75% of all diabetes-related deaths. Here we investigate the link between diabetes and ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3db9979bd5bb34ee23b4d4757d99dc
https://doi.org/10.1096/fasebj.20.4.a485
https://doi.org/10.1096/fasebj.20.4.a485
Autor:
Min Jung Park, Jonathan W. Martin, Meredith B. Barnes, Christopher B. Guest, Uzma Ahmad, Gregory G. Freund
Publikováno v:
Brain, Behavior, and Immunity. 22:27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1777200d58b9d64f49468f8c2d0e08
https://doi.org/10.1016/j.bbi.2008.04.087
https://doi.org/10.1016/j.bbi.2008.04.087
Publikováno v:
BMC Immunology
BMC Immunology, Vol 9, Iss 1, p 42 (2008)
BMC Immunology, Vol 9, Iss 1, p 42 (2008)
Background Macrophages (MΦs) utilize macropinocytosis to integrate immune and metabolic signals in order to initiate an effective immune response. Diabetes is characterized by metabolic abnormalities and altered immune function. Here we examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ce1377cf33912ad88b8c3136d77baf