Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Christopher B Buck"'
Autor:
Gabriel J Starrett, Kelly Yu, Yelena Golubeva, Petra Lenz, Mary L Piaskowski, David Petersen, Michael Dean, Ajay Israni, Brenda Y Hernandez, Thomas C Tucker, Iona Cheng, Lou Gonsalves, Cyllene R Morris, Shehnaz K Hussain, Charles F Lynch, Reuben S Harris, Ludmila Prokunina-Olsson, Paul S Meltzer, Christopher B Buck, Eric A Engels
Publikováno v:
eLife, Vol 12 (2023)
A small percentage of bladder cancers in the general population have been found to harbor DNA viruses. In contrast, up to 25% of tumors of solid organ transplant recipients, who are at an increased risk of developing bladder cancer and have an overal
Externí odkaz:
https://doaj.org/article/276cdac8c65046efa937353d38e5f7ca
Autor:
Rong Yang, Eunice E Lee, Jiwoong Kim, Joon H Choi, Elysha Kolitz, Yating Chen, Clair Crewe, Nicholas J H Salisbury, Philipp E Scherer, Clay Cockerell, Taylor R Smith, Leslie Rosen, Louisa Verlinden, Denise A Galloway, Christopher B Buck, Mariet C Feltkamp, Christopher S Sullivan, Richard C Wang
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009582 (2021)
Circular RNAs (circRNAs) are a conserved class of RNAs with diverse functions, including serving as messenger RNAs that are translated into peptides. Here we describe circular RNAs generated by human polyomaviruses (HPyVs), some of which encode varia
Externí odkaz:
https://doaj.org/article/4eb50517857d4f2caf9eb025a5a0ebc2
Autor:
Michael J Tisza, Diana V Pastrana, Nicole L Welch, Brittany Stewart, Alberto Peretti, Gabriel J Starrett, Yuk-Ying S Pang, Siddharth R Krishnamurthy, Patricia A Pesavento, David H McDermott, Philip M Murphy, Jessica L Whited, Bess Miller, Jason Brenchley, Stephan P Rosshart, Barbara Rehermann, John Doorbar, Blake A Ta'ala, Olga Pletnikova, Juan C Troncoso, Susan M Resnick, Ben Bolduc, Matthew B Sullivan, Arvind Varsani, Anca M Segall, Christopher B Buck
Publikováno v:
eLife, Vol 9 (2020)
Although millions of distinct virus species likely exist, only approximately 9000 are catalogued in GenBank's RefSeq database. We selectively enriched for the genomes of circular DNA viruses in over 70 animal samples, ranging from nematodes to human
Externí odkaz:
https://doaj.org/article/18258a977dad4b58af65b3c54e4dcb03
Autor:
Christopher B Buck, Koenraad Van Doorslaer, Alberto Peretti, Eileen M Geoghegan, Michael J Tisza, Ping An, Joshua P Katz, James M Pipas, Alison A McBride, Alvin C Camus, Alexa J McDermott, Jennifer A Dill, Eric Delwart, Terry F F Ng, Kata Farkas, Charlotte Austin, Simona Kraberger, William Davison, Diana V Pastrana, Arvind Varsani
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005574 (2016)
Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches
Externí odkaz:
https://doaj.org/article/7739ad4591ff4b3b9ba8b0164dfb5663
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003558 (2013)
The surface of polyomavirus virions is composed of pentameric knobs of the major capsid protein, VP1. In previously studied polyomavirus species, such as SV40, two interior capsid proteins, VP2 and VP3, emerge from the virion to play important roles
Externí odkaz:
https://doaj.org/article/de0d2acb4a8d419eb85da9eaa010620d
Autor:
Diana V Pastrana, Daniel C Brennan, Nicolas Cuburu, Gregory A Storch, Raphael P Viscidi, Parmjeet S Randhawa, Christopher B Buck
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002650 (2012)
BK polyomavirus (BKV or BKPyV) associated nephropathy affects up to 10% of kidney transplant recipients (KTRs). BKV isolates are categorized into four genotypes. It is currently unclear whether the four genotypes are also serotypes. To address this i
Externí odkaz:
https://doaj.org/article/35b03e41177a40098f4d2da80076af3c
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003021 (2012)
Merkel cell polyomavirus (MCV or MCPyV) is the first human polyomavirus to be definitively linked to cancer. The mechanisms of MCV-induced oncogenesis and much of MCV biology are largely unexplored. In this study, we demonstrate that bromodomain prot
Externí odkaz:
https://doaj.org/article/3beb5d177f0143688054236c7542faf7
Autor:
Ursula Neu, Holger Hengel, Bärbel S Blaum, Rachel M Schowalter, Dennis Macejak, Michel Gilbert, Warren W Wakarchuk, Akihiro Imamura, Hiromune Ando, Makoto Kiso, Niklas Arnberg, Robert L Garcea, Thomas Peters, Christopher B Buck, Thilo Stehle
Publikováno v:
PLoS Pathogens, Vol 8, Iss 7, p e1002738 (2012)
The recently discovered human Merkel cell polyomavirus (MCPyV or MCV) causes the aggressive Merkel cell carcinoma (MCC) in the skin of immunocompromised individuals. Conflicting reports suggest that cellular glycans containing sialic acid (Neu5Ac) ma
Externí odkaz:
https://doaj.org/article/e1a4070320af41d0a03d18a140ddc822
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42181 (2012)
Merkel Cell Polyomavirus (MCV or MCPyV) was recently discovered in an aggressive form of skin cancer known as Merkel cell carcinoma (MCC). Integration of MCV DNA into the host genome likely contributes to the development of MCC in humans. MCV infecti
Externí odkaz:
https://doaj.org/article/ae2064fb127741348cbf070aacd36e16
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002161 (2011)
Merkel cell polyomavirus (MCV or MCPyV) appears to be a causal factor in the development of Merkel cell carcinoma, a rare but highly lethal form of skin cancer. Although recent reports indicate that MCV virions are commonly shed from apparently healt
Externí odkaz:
https://doaj.org/article/e181bee748d043e6863a0cd4e74e0a61