Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christopher Bérubé"'
Autor:
Thomas Tremblay, Catherine Bergeron, Dominic Gagnon, Christopher Bérubé, Normand Voyer, Dave Richard, Denis Giguère
Publikováno v:
ACS Medicinal Chemistry Letters. 14:217-222
Autor:
Denis Giguère, Thomas Tremblay, Pénélope Haguette, Gabrielle Robert-Scott, Jessica B. Alcée, Christopher Bérubé, Catherine Bergeron, Normand Voyer
Publikováno v:
Synlett. 34:40-44
In this work, the synthetic development of an oxime resin aminolysis to lincosamide analogues is described. This synthetic endeavor hinges on a protecting-group-free strategy of the amino sugar nucleophiles. The cleavage from the solid support is ach
Autor:
Angana Mukherjee, Alexandre Borgia, Dave Richard, Christopher Bérubé, Dominic Gagnon, Normand Voyer
Publikováno v:
Journal of Natural Products. 83:1778-1783
Dominicin, a macrocyclic peptide isolated from the marine sponge Eurypon laughlini, has been synthesized for the first time by solid-phase peptide synthesis. The strategy uses oxime resin and takes...
Publikováno v:
Chemical Communications. 55:7434-7437
Mortiamides A-D (1-4) are head-to-tail cyclic heptapeptides that were identified from a novel Mortierella sp. isolate obtained from marine sediments from Northern Canada. Herein we report the first total synthesis of mortiamides A-D (1-4) on a solid
Publikováno v:
Tetrahedron Letters. 59:4176-4179
Taking advantage of the nucleophile-sensitive ester link of oxime resin, a novel synthetic strategy was applied to the first synthesis of a type of cyclic peptides known as pseudacyclins A–E. The endocyclic ornithine side-chain part was incorporate
Publikováno v:
Tetrahedron Letters. 92:153677
Autor:
Normand Voyer, Christopher Bérubé, Gaëlle Simon, Daniel Grenier, Pierre-Alexandre Paquet-Côté
Publikováno v:
Bioorganicmedicinal chemistry. 28(23)
The global increase in microbial resistance is an imminent threat to public health. Effective treatment of infectious diseases now requires new antimicrobial therapies. We report herein the discovery of aromatic-rich piperazines that inhibit biofilm
Publikováno v:
Phytochemistry Letters. 26:101-105
Crotogossamide, a cyclic peptide isolated from the latex of Croton gossypifolius, has been synthesized by a rapid and efficient Boc solid-phase peptide synthesis. The strategy takes advantage of the oxime resin nucleophile susceptibility and comprise
Autor:
Normand Voyer, Christopher Bérubé
Publikováno v:
Supramolecular Chemistry. 30:184-195
With the objective to develop supramolecular catalysts for useful chemical transformations, we report here a rapid and efficient solid-phase synthesis of novel cyclic dipeptides (crown-CDPs) with a diversity of L-DOPA derived crown ether substituents
Autor:
Denis Giguère, Antoine Carpentier, Normand Voyer, Thomas Tremblay, Gabrielle Robert-Scott, Christopher Bérubé
Publikováno v:
Chemical communications (Cambridge, England). 55(91)
Natural glycopeptides have been shown to possess interesting biological activities. In this work, we have developed a general solid-phase approach to C-terminal glycopeptides. Taking advantage of oxime resin ester bond nucleophile susceptibility, we