Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Christopher Arendt"'
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8980eb34badc6a19f61bbce026e67
https://doi.org/10.1158/2767-9764.c.6550691
https://doi.org/10.1158/2767-9764.c.6550691
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary tables: Supplementary Table 1 describes where cells were obtained from and details of authentication and mycoplasma testing dates. Supplementary Table 2 shows TAK-676 potency in cynomolgus monkey, human, mouse, and rat STING via time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc816185704d6e9271927a182bdb34f
https://doi.org/10.1158/2767-9764.22544570
https://doi.org/10.1158/2767-9764.22544570
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary figures: Supplementary Figure 1 shows cell viability of human monocyte-derived dendric cells and mouse bone marrow dendritic cells. Supplementary Figure 2 shows mean plasma and tumor concentration-time curves of TAK-676 in BALB/C mice (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f557c397f065d58fee34ecc2828d809
https://doi.org/10.1158/2767-9764.22544576
https://doi.org/10.1158/2767-9764.22544576
Autor:
Hong Liu, Asher Zilberstein, Pascal Pannier, Frederic Fleche, Christopher Arendt, Christoph Lengauer, Chang S. Hahn
Publikováno v:
Cancer Informatics, Vol 2012, Iss 11, Pp 15-27 (2011)
Externí odkaz:
https://doaj.org/article/0089e025faf34afab4fbc4461e9e029d
Autor:
Hong Liu, Asher Zilberstein, Pascal Pannier, Frederic Fleche, Christopher Arendt, Christoph Lengauer, Chang S. Hahn
Publikováno v:
Cancer Informatics, Vol 11 (2012)
Somatic cell genetic alterations are a hallmark of tumor development and progression. Although various technologies have been developed and utilized to identify genetic aberrations, identifying genetic translocations at the chromosomal level is still
Externí odkaz:
https://doaj.org/article/f0d8d46908264f37af25bffe84cdecf9
Autor:
Sabrina Carpentier, Sebastian Carotta, Tracy L Putoczki, Nicholas D. Huntington, Lisa A. Mielke, Stanislas Mondot, Yann M. Kerdiles, Olivier Lantz, Mohamed Lamkanfi, Eric Vivier, Wei Shi, Gordon K. Smyth, Elisabeth Wieduwild, Cyril Seillet, Aurore Fenis, Lucille C. Rankin, Gabrielle T. Belz, Tim Soos, Jean-Christophe Renauld, Sophie Ugolini, Christopher Arendt, Dieter Demon, Mathilde J. H. Girard-Madoux, Anthony T. Papenfuss
Publikováno v:
Nature immunology
Nature Immunology
Nature Immunology, 2016, 17 (2), pp.179-186. ⟨10.1038/ni.3332⟩
Nature Immunology, Nature Publishing Group, 2016, 17 (2), pp.179-186. ⟨10.1038/ni.3332⟩
Nature Immunology, Vol. 17, no.2, p. 179-186 (2015)
Nature Immunology
Nature Immunology, 2016, 17 (2), pp.179-186. ⟨10.1038/ni.3332⟩
Nature Immunology, Nature Publishing Group, 2016, 17 (2), pp.179-186. ⟨10.1038/ni.3332⟩
Nature Immunology, Vol. 17, no.2, p. 179-186 (2015)
International audience; Intestinal T cells and group 3 innate lymphoid cells (ILC3 cells) control the composition of the microbiota and gut immune responses. Within the gut, ILC3 subsets coexist that either express or lack the natural cytoxicity rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6280c9df32c4f187d7a3cdc654ef6187
https://doi.org/10.1038/ni.3332
https://doi.org/10.1038/ni.3332
Publikováno v:
BMC Bioinformatics
Background The immune system is multifaceted, structured by diverse components that interconnect using multilayered dynamic cellular processes. Genomic technologies provide a means for investigating, at the molecular level, the adaptations of the imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f274b7a273866865828d1d2c691f4536
https://pubmed.ncbi.nlm.nih.gov/27089880
https://pubmed.ncbi.nlm.nih.gov/27089880
Autor:
George Qian, Barbara Fanelli, Deborah Iglesias-Bregna, Margaret Petty, Zhongqi Ji, Garth E. Ringheim, Kathleen McMonagle-Strucko, Christopher Arendt, Nian Tian, Timothy J. Soos, Nicholas J. Colletti, Lynn Laws-Ricker, Thomas Delohery, Rajula Gaur, Jean Cavallo, Lan Lee, Daniel Weinstock, Juventas Telsinskas, Kendra Schroeder, Donghui Zhang, Li Liu
Publikováno v:
Frontiers in Neurology, Vol 4 (2013)
Frontiers in Neurology
Frontiers in Neurology
Teriflunomide is an oral disease-modifying therapy recently approved in several locations for relapsing-remitting multiple sclerosis. To gain insight into the effects of teriflunomide, immunocyte population changes were measured during progression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac712ff826bd144f25f5ffbc98d7fcbf
http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00169/full
http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00169/full
Publikováno v:
Journal of neuroimmunology. 265(1-2)
Teriflunomide is an inhibitor of dihydro-orotate dehydrogenase (DHODH), and is hypothesized to ameliorate multiple sclerosis by reducing proliferation of stimulated lymphocytes. We investigated teriflunomide's effects on proliferation, activation, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5472bc1524dea82e8ab495c85322c9f
https://pubmed.ncbi.nlm.nih.gov/24182769
https://pubmed.ncbi.nlm.nih.gov/24182769
Publikováno v:
BMC Bioinformatics
Background Genome-wide association studies can provide novel insights into diseases of interest, as well as to the responsiveness of an individual to specific treatments. In such studies, it is very important to correct for population stratification,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c66dcdb0dd131f5c991f813ba0f612b
https://doi.org/10.1186/1471-2105-14-132
https://doi.org/10.1186/1471-2105-14-132