Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Christopher Altmann"'
Autor:
Peter R. Baker, Amy S. Li, Benjamin R. Griffin, Hyo-Wook Gil, David J. Orlicky, Benjamin M. Fox, Bryan Park, Genevieve C. Sparagna, Jared Goff, Christopher Altmann, Hanan Elajaili, Kayo Okamura, Zhibin He, Daniel Stephenson, Angelo D’Alessandro, Julie A. Reisz, Eva S. Nozik, Carmen C. Sucharov, Sarah Faubel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Acute kidney injury (AKI) is a systemic disease that affects energy metabolism in various remote organs in murine models of ischemic AKI. However, AKI-mediated effects in the liver have not been comprehensively assessed. After inducing ische
Externí odkaz:
https://doaj.org/article/e75afd0af2434c049b30e596eeaa926d
Autor:
Danielle E. Soranno, Peter Baker, Lara Kirkbride-Romeo, Sara A. Wennersten, Kathy Ding, Brysen Keith, Maria A. Cavasin, Christopher Altmann, Rushita A. Bagchi, Korey R. Haefner, John Montford, Katja M. Gist, Laurent Vergnes, Karen Reue, Zhibin He, Hanan Elajaili, Kayo Okamura, Eva Nozik, Timothy A. McKinsey, Sarah Faubel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Acute kidney injury (AKI) is common in patients, causes systemic sequelae, and predisposes patients to long-term cardiovascular disease. To date, studies of the effects of AKI on cardiovascular outcomes have only been performed in male mice.
Externí odkaz:
https://doaj.org/article/6d0487175e6c4678ae581eca91856780
Autor:
Carolyn N. Brown, Daniel Atwood, Deepak Pokhrel, Sara J. Holditch, Christopher Altmann, Nataliya I. Skrypnyk, Jennifer Bourne, Jelena Klawitter, Judith Blaine, Sarah Faubel, Andrew Thorburn, Charles L. Edelstein
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-15 (2021)
Abstract Many surgical models are used to study kidney and other diseases in mice, yet the effects of the surgical procedure itself on the kidney and other tissues have not been elucidated. In the present study, we found that both sham surgery and un
Externí odkaz:
https://doaj.org/article/3eef56e0661048e78f57d957fdd0635f
Autor:
Rhea Bhargava, William Janssen, Christopher Altmann, Ana Andrés-Hernando, Kayo Okamura, R William Vandivier, Nilesh Ahuja, Sarah Faubel
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61405 (2013)
Serum and bronchoalveolar fluid IL-6 are increased in patients with acute respiratory distress syndrome (ARDS) and predict prolonged mechanical ventilation and poor outcomes, although the role of intra-alveolar IL-6 in indirect lung injury is unknown
Externí odkaz:
https://doaj.org/article/6a4de9c9e2fc47289abe34de0d5ae6ad
Autor:
Sarah Faubel, Sophia L. Ambruso, Hyo-Wook Gil, Benjamin Fox, Peter R. Baker, Rushita A. Bagchi, Bryan D. Park, Julie A. Reisz, Christopher Altmann
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Acute kidney injury (AKI) is a complex disease associated with increased mortality that may be due to deleterious distant organ effects. AKI associated with respiratory complications, in particular, has a poor outcome. In murine models, AKI is charac
Autor:
Danielle E. Soranno, Brysen Keith, DO Katja M. Gist, Kathy Ding, Rushita A. Bagchi, Timothy A. McKinsey, BS Sara A. Wennersten, John R. Montford, BS Lara Kirkbride-Romeo, BA Christopher Altmann, Korey R. Haefner, Sarah Faubel, Peter R. Baker, Maria A. Cavasin, Christian Steinkühler
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • This is the first long-term (1-year) study to evaluate both the kidney and systemic sequelae of acute kidney injury in mice. • Serial kidney function was measured via transcutaneous glomerular filtration rate.
Highlights • This is the first long-term (1-year) study to evaluate both the kidney and systemic sequelae of acute kidney injury in mice. • Serial kidney function was measured via transcutaneous glomerular filtration rate.
Autor:
Danielle E. Soranno, Lara Kirkbride‐Romeo, Daniel Han, Christopher Altmann, Christopher B. Rodell
Publikováno v:
Journal of Biomedical Materials Research Part A. 110
Autor:
Daniel Han, Christopher B. Rodell, Lara Kirkbride-Romeo, Christopher Altmann, Danielle E. Soranno
Publikováno v:
Journal of biomedical materials research. Part A. 110(3)
The continued development of minimally invasive therapeutic implants, such as injectable hydrogels, necessitates the concurrent advancement of methods to best assess their biocompatibility via functional outcomes in vivo. Biomaterial implants have be
Autor:
Lara A. Kirkbride-Romeo, Danielle E. Soranno, Hyo-Wook Gil, Sarah Faubel, Christopher Altmann, John R. Montford, Jane Buchanan, Ani Levine, Haichun Yang
Publikováno v:
J Am Soc Nephrol
Background The duration of renal ischemia that is associated with (or leads to) renal injury in patients is uncertain, and a reverse translational research approach has been proposed to improve animal models of AKI to facilitate clinical translatabil
Autor:
Mary C.M. Weiser-Evans, Emily K. Kleczko, Bonnie L. Bullock, Peter C. Harris, Katharina Hopp, Christopher Altmann, Seth B. Furgeson, Raphael A. Nemenoff, Logan C. Tyler, Michel Chonchol, Eric T. Clambey, Berenice Gitomer, Makoto Miyazaki, Kenneth H. Marsh
Publikováno v:
Kidney International. 94:1127-1140
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent inherited nephropathy. To date, therapies alleviating the disease have largely focused on targeting abnormalities in renal epithelial cell signaling. ADPKD has many hallmarks